MISSION-CJ for Dual Diagnosis

(STAR-R Trial)

Not yet recruiting at 1 trial location
DS
MA
Overseen ByMichael Andre, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Massachusetts, Worcester
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a support program for individuals with both substance use and mental health disorders who are released from jail. The study compares two approaches: a full program with structured treatment (MISSION-CJ) and support that links participants to community services (Peer Linkage Support). Researchers aim to determine which method more effectively aids sobriety and mental health improvement. Individuals released from a participating jail with both a substance use and mental health disorder may be suitable for this trial. As an unphased trial, this study provides a unique opportunity to enhance understanding of effective support methods for individuals in similar situations.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that the MISSION-CJ and Peer Linkage Support interventions are safe for individuals with co-occurring disorders?

Research has shown that the MISSION-CJ program is safe for participants. One study found that it reduced alcohol and drug use, lowered anxiety, and decreased the number of nights participants spent in jail. Participants did not report any major negative effects, indicating the program is generally well-received and helpful for individuals with both substance use and mental health issues.

Peer Linkage Support connects participants to community services. Although specific safety data for this program might not be detailed, peer support models are generally recognized as safe and supportive in mental health and substance use situations.

Overall, these findings suggest that both MISSION-CJ and Peer Linkage Support are safe and may benefit those dealing with both substance use and mental health challenges.12345

Why are researchers excited about this trial?

Researchers are excited about MISSION-CJ and Peer Linkage Support because they offer a fresh approach to treating individuals with dual diagnosis, which involves both mental health and substance use disorders. Unlike standard treatments that often focus separately on mental health or substance use, MISSION-CJ integrates both into a cohesive 6-month program. This comprehensive care includes a structured curriculum directed by a Case Manager and a Peer Support Specialist, which is not commonly found in current treatment plans. Meanwhile, Peer Linkage Support focuses on providing community-based connections and informal treatment planning through a Peer Specialist, offering a supportive yet distinct alternative to more integrated treatments. Both approaches emphasize community linkages and peer support, setting them apart from traditional methods that may not fully address the dual nature of these diagnoses.

What evidence suggests that this trial's treatments could be effective for co-occurring substance use and mental health disorders?

Research has shown that the MISSION-CJ program, which participants in this trial may receive, can assist individuals with both mental health issues and substance use problems. Studies have found that participants often use fewer illegal drugs, experience fewer trauma symptoms, and spend less time in jail. The MISSION approach is also associated with improved mental health and more stable housing. In special court settings, past participants demonstrated good treatment results, suggesting that MISSION-CJ could be a helpful option for people facing these dual challenges. Meanwhile, the Peer Linkage Support arm, another treatment option in this trial, focuses on providing linkage care and support to community services, serving as a comparison group to the MISSION-CJ arm.678910

Who Is on the Research Team?

DS

David Smelson, PsyD

Principal Investigator

University of Massachusetts, Worcester

PS

Paige Shaffer, PhD

Principal Investigator

University of Massachusetts, Worcester

Are You a Good Fit for This Trial?

This trial is for adults (18+) who can read and write English, have just been released from certain Massachusetts jails, and have both a substance use disorder and a mental health condition like depression, anxiety, trauma-related disorders, bipolar disorder, or schizophrenia. People who are currently very suicidal or psychotic cannot join.

Inclusion Criteria

Proficient in reading and writing in the English language
Released from one of the participating jails
Have a current co-occurring substance use and mental health disorder, which includes any substance use disorder (including alcohol) and mental health disorder (including depression, anxiety, trauma related disorders, bipolar, and/or schizophrenia) as documented by the participating jails
See 1 more

Exclusion Criteria

Acutely suicidal based on the CSSRS
Acutely psychotic based on SCID-5-RV

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 6 months of integrated mental health and substance use treatment through MISSION-CJ or Peer Linkage Support

6 months
Regular sessions with case managers and peer specialists

Follow-up

Participants are monitored for engagement in treatment, recidivism, and health outcomes post-treatment

6 months
Follow-up assessments at 3, 6, 9, and 12 months post enrollment

What Are the Treatments Tested in This Trial?

Interventions

  • MISSION-CJ
  • Peer Linkage Support

Trial Overview

The study compares two support programs after jail release: the full MISSION-CJ program (which offers coordinated care for addiction and mental health) versus Peer Linkage Support. The goal is to see which helps people stay in treatment and improve their recovery.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Full MISSION-CJExperimental Treatment1 Intervention
Group II: Peer Linkage SupportActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Massachusetts, Worcester

Lead Sponsor

Trials
372
Recruited
998,000+

Cornell University

Collaborator

Trials
179
Recruited
14,090,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

1.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/31337322/

Implementation of MISSION-Criminal Justice in a ...

Preliminary 6-month outcomes showed significant reduction in nights incarcerated (p<0.002), illegal drug use (p<0.003), trauma symptoms (p<0.004) ...

Research Findings

Previous studies examining the efficacy of the MISSION approach have shown improved outcomes related to substance use, psychological functioning, housing, ...

A co-occurring disorders intervention for drug treatment court

We have completed several pilot studies with MISSION-CJ in specialty court settings that have shown some promising results for treatment ...

Implementation of MISSION–Criminal Justice in a ...

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Individuals with co-occurring disorders (CODs) face unique challenges when seeking evidence-based treatment compared with individuals with a mental illness or a ...

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This article reports on the implementation, evaluation, and policy implications of MISSION-Criminal Justice (CJ), an innovative intervention ...

Addressing Co-occurring Mental Health and Substance Abuse ...

Workgroup's mission to facilitate service advancements for people with a dual diagnosis in. D.C.'s criminal justice system. To this end, national research ...

MISSION-CJ for Dual Diagnosis · Info for Participants

The research will examine engagement in treatment, behavioral health outcomes, mediators and moderators, an economic analysis, and facilitators ...

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