165 Participants NeededMy employer runs this trial

Mindfulness-based Music Therapy for Stem Cell Transplantation

FJ
SE
Overseen BySara E Fleszar-Pavlovic, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Miami
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests two types of online mindfulness programs to determine their effectiveness in improving well-being during stem cell transplants. The goal is to enhance overall quality of life and reduce transplant-related symptoms. One group will engage in eHealth mindfulness-based music therapy, while the other will practice eHealth mindfulness meditation. Individuals diagnosed with blood cancer and planning a stem cell transplant may be suitable candidates, particularly if they have not recently participated in similar therapy programs. As an unphased trial, this study provides a unique opportunity to explore innovative therapies that could enhance well-being during treatment.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that mindfulness meditation is generally safe and carries few risks. Studies have found that both eHealth Mindfulness-based Music Therapy (eMBMT) and eHealth Mindfulness Meditation (eMM) are well-tolerated by patients, with no reports of serious side effects.

Early studies on eHealth Mindfulness-based Music Therapy with patients undergoing stem cell transplants have not identified any major safety issues. Similarly, research on eHealth Mindfulness Meditation indicates it is a safe practice with few negative effects reported.

Overall, mindfulness practices like these are often considered safe and low-risk, making them a promising option for those seeking additional support during medical treatments.12345

Why are researchers excited about this trial?

Researchers are excited about these treatments because they explore the unique combination of mindfulness and music therapy delivered through eHealth platforms. Unlike traditional methods for managing stress and improving quality of life during stem cell transplantation, which often involve medication and in-person therapy sessions, these approaches offer the flexibility of practicing mindfulness and music therapy from home. This makes it more accessible for patients who may be dealing with the physical and emotional challenges of transplantation. Additionally, integrating music with mindfulness has the potential to enhance relaxation and emotional well-being, offering a holistic alternative to standard care practices.

What evidence suggests that this trial's treatments could be effective for improving health-related quality of life in patients undergoing stem cell transplantation?

This trial will compare two treatments: eHealth Mindfulness-based Music Therapy (eMBMT) and eHealth Mindfulness Meditation (eMM). Studies have shown that mindfulness-based music therapy can enhance quality of life and reduce symptoms for patients undergoing stem cell transplants. This approach combines music and mindfulness techniques to improve mental and physical well-being. Research indicates that these therapies can alleviate symptoms like anxiety and stress, which are common in these patients. Mindfulness meditation, delivered through electronic health (eHealth) platforms, has also supported these benefits. Both treatments in this trial aim to make mindfulness practices more accessible, enhancing overall well-being during a challenging time.12367

Who Is on the Research Team?

FJ

Frank J Penedo, PhD

Principal Investigator

University of Miami

Are You a Good Fit for This Trial?

This trial is for adults (18 or older) who speak English or Spanish, have a blood cancer like leukemia, lymphoma, or myelodysplastic syndrome, and are scheduled to receive a stem cell transplant.

Inclusion Criteria

I have a plan to receive a stem cell transplant.
I have been diagnosed with a blood cancer like MDS, AML, ALL, or NHL.
I can speak English or Spanish.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive eHealth Mindfulness-based Music Therapy or Mindfulness Meditation for 5 months

5 months

Follow-up

Participants are monitored for changes in health-related quality of life, pain, fatigue, cognitive function, sleep quality, and other health metrics

up to 18 months

What Are the Treatments Tested in This Trial?

Interventions

  • eHealth Mindfulness-based Music Therapy
  • eHealth Mindfulness Meditation

Trial Overview

The study compares two online programs: one combines mindfulness with music therapy (eMBMT), and the other uses mindfulness meditation alone (eMM). The goal is to see which helps improve quality of life during stem cell transplantation.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: eHealth Mindfulness-based Music Therapy (eMBMT)Experimental Treatment1 Intervention
Group II: eHealth Mindfulness Meditation (eMM)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Miami

Lead Sponsor

Trials
976
Recruited
423,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Citations

1.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/38763308/

eHealth mindfulness-based music therapy for patients ...

Results will inform a fully powered RCT to establish preliminary efficacy of eMBMT on improvements in HRQOL, symptom burden, and disease ...

eHealth Mindfulness-based Music Therapy Intervention for ...

The goal of this study is to test an electronic health (eHealth) mindfulness-based music therapy intervention to improve health-related quality of life and ...

eHealth mindfulness-based music therapy for patients ...

Results will inform a fully powered RCT to establish preliminary efficacy of eMBMT on improvements in HRQOL, symptom burden, and disease activity. Introduction.

4.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40215402/

Development of an eHealth Mindfulness-Based Music ...

The eMBMT intervention is a comprehensive, user-friendly eHealth tool tailored to the unique needs of allo-SCT patients.

eHealth Mindfulness-based Music Therapy Intervention for ...

The goal of this study is to test an electronic health (eHealth) mindfulness-based music therapy intervention to improve health-related ...

eHealth Mindfulness-based Music Therapy for Patients ... - PMC

eHealth Mindfulness-based Music Therapy for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Pilot Randomized Controlled Trial Protocol.

Electronic Health Mindfulness-based Music Therapy ...

The goal of this study is to pilot test an Electronic Health Mindfulness-based Music Therapy Intervention (eMBMT) intervention to improve health-related ...