200 Participants NeededMy employer runs this trial

Self-Sampling for Cervical Cancer Screening

RA
Overseen ByResearch Administrator
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Rochester
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new method to simplify cervical cancer screening by allowing patients to collect their own samples in the Emergency Department. The researchers aim to determine if self-collection during an ED visit increases participation in screening. This approach may suit cisgender women and transgender/non-binary individuals with a cervix, aged 30 to 65, who haven't had a hysterectomy and aren't currently pregnant. As an unphased trial, it provides a unique opportunity to contribute to innovative screening methods that could enhance accessibility and convenience for many individuals.

Do I need to stop my current medications for the trial?

The trial information does not specify if you need to stop taking your current medications. However, it does mention avoiding certain vaginal products and activities shortly before the screening.

What prior data suggests that this self-sampling method is safe for cervical cancer screening?

Research has shown that collecting one's own sample for HPV (human papillomavirus) testing is a safe and easy way to screen for cervical cancer. Many studies have found that women consider this method simple and comfortable, whether at home or in places like emergency rooms.

No serious side effects have been reported with this self-sampling method. It involves using a swab to collect a sample, which is then sent to a lab for testing. This approach is considered an effective way to make cervical cancer screening more accessible, especially for those who don't visit a clinic regularly.

Overall, self-sampling for HPV offers a safe option for women who want to participate in cervical cancer screening.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a convenient and potentially more accessible method for cervical cancer screening. Unlike traditional Pap smears or HPV tests, which require a clinic visit and a healthcare provider to collect samples, this new approach allows women to self-sample for HPV in the privacy of an emergency department room. This method could increase screening rates by making it easier for women to get tested, especially those who might not have easy access to regular healthcare visits. By simplifying the process and offering a private, patient-controlled option, this trial aims to improve early detection and ultimately reduce cervical cancer rates.

What evidence suggests that self-sampling is effective for cervical cancer screening?

Research has shown that allowing women to collect their own samples for HPV (human papillomavirus) testing increases cervical cancer screening rates. Studies find that women feel comfortable with self-sampling and are more likely to get screened when they can do it themselves. This trial will test the effectiveness of offering self-sampling options in the emergency department, potentially leading to more women getting screened. Overall, HPV self-sampling offers a promising way to encourage more women to participate in cervical cancer screening programs.12367

Are You a Good Fit for This Trial?

This trial is for people aged 30-65 with a cervix (cisgender women and some transgender/non-binary individuals) who visit the emergency department, can give consent, and haven't recently used vaginal products or had certain exams. People who've had their cervix removed, are pregnant/recently gave birth, have HIV, or can't consent can't join.

Inclusion Criteria

I am between 30 and 65 years old and able to make my own medical decisions.
I have a cervix.

Exclusion Criteria

I have used vaginal products or contraceptives in the past 3 days.
I have had my uterus and cervix surgically removed.
Known infection with HIV (as screening recommendations for people with HIV differ from the general population)
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 day
1 visit (in-person)

Intervention

Participants are provided the opportunity to self-sample for HPV during their ED visit

1 day
1 visit (in-person)

Follow-up

Follow-up to determine cervical cancer screening activity, perceived and concrete barriers to care, and participant experiences with the intervention

150 days

What Are the Treatments Tested in This Trial?

Interventions

  • Emergency Department-based Cervical Cancer Screening Through Self-sampling

Trial Overview

The study tests if offering cervical cancer screening using self-collected HPV samples in the emergency department increases screening rates among eligible patients compared to usual care.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Intervention ArmExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Rochester

Lead Sponsor

Trials
883
Recruited
555,000+

Citations

Study Details | NCT06796738 | Advancing Cervical Cancer ...

Participants will be (1) briefly instructed by the study staff on how to self-sample using a defined instructional script written at an elementary reading level ...

Evaluation of the Impact of Human Papillomavirus DNA Self ...

This study explored the acceptability of HPV DNA self-sampling and its impact on the rate of compliance with cervical cancer screening.

Self-Collection for Primary HPV Testing: Acceptability in a ...

In summary, our data suggest that HPV self-collection was well accepted by underscreened women waiting to receive noncritical care at the safety ...

Emergency Department-based Cervical Cancer Screening ...

This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.

Self-Sampling for HPV in the Emergency Department to ...

This clinical trial compares the impact of high-risk human papillomavirus (hrHPV) self-sampling in the emergency department (ED) to a historical control ...

Medscape

Emergency department (ED)-based screening interventions for cervical cancer resulted in documented screening in 1 of 6 patients, with higher ...

Self-Sampling for Human Papillomavirus Testing - PMC - NIH

Self-sampling for human papillomavirus testing is increasingly recognized as a strategy to expand cervical cancer screening access and utilization.