Apple Cider Vinegar for Kidney Stones

LR
Overseen ByLuke Reynolds
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how apple cider vinegar (ACV) affects urine chemistry, potentially aiding in kidney stone management. Researchers aim to determine if daily ACV intake over a short period can make a difference. Participants include individuals with a history of calcium oxalate kidney stones and those without kidney stones. The trial seeks individuals who have primarily experienced calcium oxalate kidney stones and have not recently used ACV beyond normal consumption. As an unphased trial, it offers a unique opportunity to contribute to understanding potential natural remedies for kidney stones.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that apple cider vinegar is safe for kidney stone patients and healthy participants?

Research shows that apple cider vinegar (ACV) is generally safe for consumption. Studies have found that daily vinegar intake can reduce the recurrence of kidney stones and improve certain urine markers, such as citrate and calcium, which benefit kidney health.

Although ACV is not a medicine, its long history of use in food suggests that most people tolerate it well. Studies examining its use for kidney stones have not reported major side effects. However, as with any dietary change, monitoring the body's reaction is important. Consulting a healthcare provider is advisable if there are concerns or unusual symptoms.12345

Why are researchers excited about this trial?

Unlike the standard kidney stone treatments that often involve medication to help pass the stones, pain management, or even surgical procedures, apple cider vinegar (ACV) is a natural remedy that offers a unique approach. Researchers are excited about ACV because it contains acetic acid, which may help dissolve kidney stones and prevent new ones from forming. Additionally, ACV's delivery method as a gummy makes it easy and convenient for daily consumption, especially for those who prefer to avoid pills or invasive treatments.

What evidence suggests that apple cider vinegar might be an effective treatment for kidney stones?

Research has shown that apple cider vinegar (ACV) might help with kidney stones. One study found that daily vinegar intake reduced the recurrence of stones by increasing citrate and decreasing calcium in urine. More citrate in the urine can lower the risk of kidney stones. The acidic nature of ACV might also help break down kidney stones, making them easier to pass. In this trial, participants will consume an ACV gummy daily for 14 consecutive days to evaluate its potential as a helpful addition to current kidney stone treatments.13467

Who Is on the Research Team?

LR

Luke Reynolds

Principal Investigator

The University of Chicago Medical Center

Are You a Good Fit for This Trial?

This trial is for adults over 18 with a history of mostly calcium oxalate kidney stones. It's not for those who've had mainly calcium phosphate or struvite stones, frequent UTIs, chronic kidney disease, acid-base disorders, recent ACV use or negative reactions to it, uric acid stones, or recent urinary tract procedures.

Inclusion Criteria

I am over 18 years old.
I am over 18 and have kidney stones.
Most of my kidney stones are made of calcium oxalate.

Exclusion Criteria

I have had kidney stones made mostly of calcium phosphate.
I have had multiple urinary tract infections.
I have a history of chronic kidney disease.
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week
1 visit (in-person)

Treatment

Participants consume an ACV gummy containing 60 meq daily for 14 consecutive days

2 weeks
No additional visits required

Follow-up

Participants are monitored for changes in urine chemistry after treatment

2 weeks
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Apple Cider Vinegar

Trial Overview

The study tests the effects of daily apple cider vinegar supplementation on urine chemistry in adults. Participants will take ACV every day and researchers will monitor how this affects the substances in their urine that could relate to kidney stone formation.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: kidney stone patients and healthy participantsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Chicago

Lead Sponsor

Trials
1,086
Recruited
844,000+

Citations

Dietary vinegar prevents kidney stone recurrence via ... - PMC

Results from a pilot clinical study indicated that daily intake of vinegar reduced stone recurrence, increased citrate and reduced calcium in urinary excretion ...

Apple Cider Vinegar for the Prevention of Urinary Lithiasis ...

Higher urinary citrate levels have been shown to decrease one's risk of developing kidney stones. The study will compare apple cider vinegar, coconut water, ...

Apple cider vinegar for prevention of urinary lithiasis (APUL)

To evaluate the potential stone-preventative effects of apple cider vinegar (ACV) supplementation on 24-h urinary citrate, pH, and volume.

How to Use Apple Cider Vinegar for Kidney Stones

The acidic nature of ACV helps reduce the size of kidney stones by breaking them down over time. Once the stones are smaller, they can pass more ...

GC–MS based metabolite profiling, antioxidant and ... - PMC

ACV can be consumed to prevent kidney stones which seems helpful to the current therapy. Keywords: antioxidant, antiurolithiatic, apple cider ...

The Effect of Apple Cider Vinegar Supplementation on 24- ...

Kidney stone patients: Adults above the age of 18. History of majority (>50%) calcium oxalate kidney stones. Exclusion Criteria: Anyone with a ...

Does Apple Cider Vinegar Really Help with Kidney Stones?

Apple cider vinegar contains small amounts of potassium, a mineral that may help prevent kidney stone formation. A 2016 study found that higher ...