12 Participants NeededMy employer runs this trial

kTMP for Stroke Recovery

Recruiting at 1 trial location
LL
Overseen ByLudovica Labruna, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new method called kTMP, a gentle form of brain stimulation, to help people regain arm and hand movements after a stroke. Participants will receive either the actual kTMP treatment or a sham (fake) version to compare effectiveness. The trial seeks individuals who had a stroke at least a year ago and still struggle with arm or hand use. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could enhance recovery options for stroke survivors.

Do I have to stop taking my current medications for the trial?

The trial information does not specify if you need to stop taking your current medications. However, if you have had seizures in the last 12 months while on anti-epilepsy medication, you may not be eligible to participate.

What prior data suggests that this technique is safe for stroke recovery?

Research has shown that kTMP, or kilohertz transcutaneous magnetic perturbations, could safely aid stroke recovery. Early findings suggest that this treatment uses gentle magnetic pulses without causing serious side effects. Studies have found that patients experience no discomfort or sensations during the treatment. This non-invasive and painless process offers a promising option for those concerned about side effects or pain.12345

Why are researchers excited about this trial?

Unlike the standard treatments for stroke recovery, which often involve physical therapy and medications like clot busters or anticoagulants, kTMP offers a unique approach through targeted electromagnetic stimulation. Researchers are excited because kTMP uses an active stimulation of 8 V/m electric fields, a new method that could enhance brain recovery by directly influencing neural activity. This innovative mechanism may offer a safer, non-invasive alternative with potentially faster and more effective results than traditional therapies.

What evidence suggests that kTMP is effective for stroke recovery?

Research has shown that repetitive transcranial magnetic stimulation (rTMS) can improve movement and thinking skills after a stroke. In this trial, participants will receive either active kTMP or sham kTMP. kTMP, a similar low-intensity method, may aid in the recovery of arm and hand functions for stroke patients. Tests with healthy individuals suggest that kTMP might enhance movement. Other studies have found that similar magnetic techniques can improve motor skills by 15-25% and boost thinking abilities by 10-20% when combined with rehabilitation. Although researchers are still studying this technique, early results are promising for aiding stroke recovery.12467

Are You a Good Fit for This Trial?

This trial is for adults who have ongoing arm or hand weakness after having a stroke. Participants should be medically stable and able to take part in rehabilitation activities.

Inclusion Criteria

I can understand information and give my consent to participate.
Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive)
My arm function score is between 20 and 50 on the Fugl-Meyer Assessment.
See 1 more

Exclusion Criteria

I have had a serious side effect from TMS in the past.
Permanent eye liner or head tattoos
Participants with moderate or severe cognitive impairment (MoCA < 18)
See 10 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Treatment

Participants receive kTMP or sham stimulation three times a week for 6 weeks

6 weeks
18 visits (in-person)

Mid-treatment Assessment

Assessment to evaluate improvement from 4 to 6 weeks of treatment

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 months
3 visits (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • kTMP

Trial Overview

The study is testing whether a new, gentle brain stimulation method called kTMP can help improve arm and hand movement after stroke. Some participants will get real kTMP, while others receive sham (inactive) treatment for comparison.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Active kTMPExperimental Treatment1 Intervention
Group II: Sham kTMPPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Magnetic Tides

Lead Sponsor

Trials
2
Recruited
220+

University of California, San Francisco

Collaborator

Trials
2,636
Recruited
19,080,000+

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator

Trials
1,403
Recruited
655,000+

Citations

Evidence of rTMS for Motor or Cognitive Stroke Recovery

CONCLUSIONS: Repetitive transcranial magnetic stimulation holds the potential to benefit a range of motor and cognitive outcomes after stroke, ...

kTMP-Enhanced Motor Rehabilitation for Chronic Stroke ...

The goal of this pilot clinical trial is to assess the feasibility and preliminary efficacy of kTMP on upper limb motor recovery in chronic ...

Repetitive transcranial magnetic stimulation in stroke ... - PMC

Their results show a positive effect in all stroke phases, either for HF-rTMS applied over the ipsilesional M1 or for LF-rTMS over the contralesional hemisphere ...

Repetitive Transcranial Magnetic Stimulation for Motor ...

Repetitive transcranial magnetic stimulation (rTMS) has shown promising results in enhancing motor recovery after stroke, but nuances regarding its use, ...

kTMP for Stroke · Info for Participants · Clinical Trial 2026

Research shows that kTMP, or kilohertz transcutaneous magnetic perturbations, might improve movement in stroke survivors. Earlier tests with healthy individuals ...

6.

magnetictides.com

magnetictides.com/science

Science

No Surgery Required: kTMP safely achieves the stimulation intensity required for recovery, delivered entirely non-invasively from outside the head, eliminating ...

Berkeley startup, Magnetic Tides, has developed a new ...

It is imperceptible, with patients reporting no side effects, discomfort or sensations whatsoever. The data enabled Magnetic Tides to win a ...