Relationship-Centered HIV Prevention for African Immigrants

(MiST-Pathways Trial)

GA
Overseen ByGloria A. Aidoo-Frimpong, PhD, MPH, MA
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: State University of New York at Buffalo
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how migration experiences and personal relationships influence HIV prevention choices among first-generation African immigrants in New York and Massachusetts. Participants will join group discussions to help create a community-focused HIV prevention program and will receive a relationship-centered HIV prevention intervention designed to promote HIV testing and prevention communication. The trial aims to determine if this approach increases interest in HIV testing and prevention measures. It suits African immigrants who have internet access and are comfortable communicating in English. As an unphased trial, this study allows participants to contribute to innovative HIV prevention strategies tailored to their community.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on interviews and group discussions rather than medication changes.

What prior data suggests that this relationship-centered HIV prevention intervention component is safe?

In a previous study, researchers examined how HIV prevention programs can be tailored to the cultural needs of African-born individuals living in the U.S. They found that participants generally received and accepted these programs well. This finding suggests that the Relationship-Centered HIV Prevention Intervention, developed with community input, is likely to be well-tolerated and safe for participants.

The main goal is to understand and enhance how African immigrants make decisions about preventing HIV. Reports of physical side effects are absent because the intervention focuses on behavior. The program includes group discussions and surveys, designed to be safe and supportive, helping participants adopt safer practices without causing harm.

Overall, the intervention seems to be a safe option for those interested in learning more about HIV prevention in their communities.12345

Why are researchers excited about this trial?

Researchers are excited about the Relationship-Centered HIV Prevention Intervention because it focuses on communication and decision-making within relationships, particularly for African immigrants. Unlike traditional HIV prevention methods that often emphasize individual behavior change or medication, this intervention is delivered via Zoom and tailors its approach based on community input and relationship dynamics shaped by migration experiences. This personalized and community-driven method may enhance its effectiveness and adaptability, making it a promising alternative to existing HIV prevention strategies.

What evidence suggests that this relationship-centered HIV prevention intervention component is effective for HIV prevention among African immigrants?

Research has shown that involving peers can encourage more immigrants to get tested for HIV. This is particularly important for African immigrants who face unique challenges due to their migration experiences and social connections. In this trial, participants will receive a relationship-centered HIV prevention intervention component via Zoom, focusing on relationship-based HIV prevention communication and decision-making within migration-shaped relationship contexts. One study found that community-focused methods, such as relationship-based communication, can help reduce stigma and improve HIV prevention efforts. These methods are tailored to the cultural and social backgrounds of African immigrants, which has been shown to increase their willingness to get tested for HIV and consider preventive measures. The goal is to enhance HIV prevention by focusing on communication that builds relationships.16789

Who Is on the Research Team?

GA

Gloria A. Aidoo-Frimpong, PhD, MPH, MA

Principal Investigator

State University of New York at Buffalo

Are You a Good Fit for This Trial?

This trial is for first-generation African immigrants aged 18 to 50 who live in New York or Massachusetts, can speak basic English, have internet access via smartphone or computer, and are willing to give consent.

Inclusion Criteria

* Self-identify as a first-generation African immigrant (born in an African country and currently residing in the United States)
* Currently reside in New York or Massachusetts
* Able to communicate in English at approximately a 3rd-grade reading level
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Qualitative Interview and Survey

Participants complete a qualitative interview and/or a structured electronic survey about their relationship experiences, migration history, and HIV prevention behaviors.

1-2 weeks
1 visit (in-person or virtual)

Palava Hut Conversation

Participants take part in a structured group deliberation session to co-develop and prioritize HIV prevention intervention ideas.

3-4 hours
1 session (in-person)

Intervention Delivery

Participants receive the prioritized intervention component in a structured Zoom session.

1 session
1 session (virtual)

Follow-up

Participants complete a follow-up survey and an optional cognitive interview to assess feasibility, acceptability, and perceived fit.

1-2 weeks
1 visit (virtual)

What Are the Treatments Tested in This Trial?

Interventions

  • Relationship-Centered HIV Prevention Intervention Component

Trial Overview

The study is testing a relationship-focused HIV prevention program co-developed with the community. All participants receive the same intervention through group discussions and online sessions; there is no comparison group.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Proof of Concept AssessmentExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

State University of New York at Buffalo

Lead Sponsor

Trials
279
Recruited
52,600+

Yale University

Collaborator

Trials
1,963
Recruited
3,046,000+

Yale University Center for Interdisciplinary Research on AIDS

Collaborator

Trials
1
Recruited
320+

Citations

MiST Pathways Study Protocol and Statistical Analysis Plan

• To generate implementation-relevant data to inform refinement for a future R34 relationship- centered HIV prevention intervention development ...

Relationship-Centered HIV Prevention for African ...

The goal of this mixed-methods pilot study is to learn whether migration experiences, social bonds, and transnational ties shape HIV ...

Peer interventions to improve HIV testing uptake among ...

This realist review aims to understand why, how, and under what conditions peer interventions can improve immigrants' HIV testing uptake.

Lessons Learned o - Brandeis ScholarWorks

Objectives were for participants to: (1) learn promising practices and strategies to provide HIV services to African immigrants; (2) discuss ...

The Tulumbe! Partnership: a case study in developing ...

A community-centered approach to HIV research is critical for African immigrants living in the United States, who experience stigma and other socio-structural ...

Evaluating the Cultural Adaptation of Evidence-Based HIV ...

African-born Black women living in the US experience markedly higher rates of HIV diagnosis than their US-born counterparts, with condom use and ...

Interventions for HIV prevention and treatment among ...

This scoping review aimed to assess publications focused on interventional HIV research with Haitian and Haitian-descent populations.

Bridging the knowledge gap of biomedical HIV prevention ...

In 2021, there were an estimated 5013 new HIV-positive cases, 32% of which involved people born in sub-Saharan Africa (Santé Publique France, 2022), whereas the ...

Perceptions of HIV Testing Among African-Born Immigrants in ...

The purpose of this dissertation was to investigate the perceptions, attitudes, and acceptability of HIV testing and how these contextual ...