Intelligent Adaptive System for Mild Cognitive Impairment

Not yet recruiting at 2 trial locations
SP
XL
Overseen ByXin Lin, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Weill Medical College of Cornell University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial is developing an innovative software tool called the Intelligent Adaptive System to assist older adults with mild cognitive impairment (MCI) by providing cognitive and social support. The software adjusts to users' needs and abilities, offering features like memory aids and social activities. Participants will use a tablet with the program and receive training on using the device and internet safely. The trial seeks individuals diagnosed with mild cognitive impairment who can read English and do not have major vision or hearing problems. As an unphased trial, this study offers a unique opportunity to contribute to the development of a potentially life-enhancing tool for those with MCI.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this Intelligent Adaptive System is safe for older adults with mild cognitive impairment?

Research has shown that the Intelligent Adaptive System could safely assist older adults with mild cognitive impairment (MCI). In past studies, similar technology did not cause any serious side effects or safety issues. For instance, these systems were tested and found safe and easy to use for people with MCI, with many completing the recommended activities. This indicates that most people manage these systems well.

Although this trial lacks its own safety data, the Intelligent Adaptive System is designed to adjust to each user's needs, potentially increasing comfort and reducing risks. Additionally, the technology is non-invasive, meaning it does not enter the body, which lowers the chance of physical side effects. Overall, evidence suggests that using this system should be safe for participants.12345

Why are researchers excited about this trial?

Most treatments for mild cognitive impairment (MCI) often involve medications or cognitive training exercises. However, the Intelligent Adaptive System stands out because it uses a personalized, technology-driven approach to support cognitive function. This system is unique as it provides participants with a tablet-based program tailored to their individual needs, offering interactive tasks and feedback. Additionally, the system includes internet training and security, ensuring users can engage safely and effectively online. Researchers are excited about this approach because it leverages technology to potentially enhance cognitive abilities in a more engaging and secure manner than traditional methods.

What evidence suggests that this Intelligent Adaptive System is effective for mild cognitive impairment?

Studies have shown that flexible learning methods can enhance thinking skills, particularly for those who engage in focused mental exercises. Research indicates that mental activities generally improve brain function over time. Evidence also suggests that keeping the mind active significantly benefits people with mild memory problems, encouraging engagement and improvement. Additionally, AI-based tools have proven highly accurate in identifying and diagnosing mild memory issues, aiding early and effective treatment. This trial will evaluate an Intelligent Adaptive System designed to boost mental and social activity for older adults with mild memory problems. Participants in the active intervention group will receive a tablet with the adaptive program and internet service, while those in the waitlist control group will receive similar training and support but will not immediately use the adaptive program. These findings suggest that a smart, adaptable system could improve outcomes for individuals with mild cognitive impairment.12367

Who Is on the Research Team?

SJ

Sara J Czaja, PhD

Principal Investigator

Weill Medical College of Cornell University

Are You a Good Fit for This Trial?

This trial is for adults aged 62 and older who have been diagnosed with mild cognitive impairment (MCI). Participants should be able to read English at a basic level, have fair vision (with or without glasses), and not have major problems doing daily tasks on their own.

Inclusion Criteria

I have been diagnosed with mild cognitive impairment.
* Subjective cognitive complaints
* Evidence by clinical evaluation
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Phase 1

Feasibility study of technology-based approaches to support everyday activities and cognition for persons with MCI

Not specified

Phase 2

Pilot testing to evaluate feasibility, acceptability, and usability of the system with individuals with MCI

6 months
In-home assessments

Follow-up

Participants are monitored for safety and effectiveness after intervention

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Intelligent Adaptive System

Trial Overview

The study is testing an intelligent adaptive software designed to support thinking skills and social engagement in older adults with MCI. The system adjusts to each user's needs, aiming to help as cognition changes over time.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Project 2 - Phase 2: Active Intervention GroupExperimental Treatment1 Intervention
Group II: Project 2 - Phase 2: Waitlist ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Weill Medical College of Cornell University

Lead Sponsor

Trials
1,103
Recruited
1,157,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+

Citations

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Evaluating the Effectiveness of Cognitive Interventions for ...

Extensive research indicates that cognitive interventions can lead to a general improvement in cognitive functioning throughout the lifespan.

Effectiveness of cognitive stimulation for individuals with ...

Our findings suggest a significant positive impact of CS on cognitive function among individuals with MCI. CS encourages the active involvement of individuals ...

AI-Based Classification of Mild Cognitive Impairment and ...

The overall accuracy and precision achieved by the model were 83.2% and 86.3%, respectively, demonstrating its potential for AI-assisted diagnostics. The ...

AI-Supported Cognitive Rehabilitation for Older Adults With ...

Secondary outcomes at 6 and 12 months include additional measures of cognition, subjective memory, goal attainment, mood, and loneliness.

Examining Technology Perspectives of Older Adults With Mild ...

Mild cognitive impairment (MCI) affects a person's memory or how they think, feel, or behave. It is not a normal part of aging, but up to 20% of ...