Mediterranean Diet for Breast Cancer

(PRIME Trial)

This trial explores whether a Mediterranean diet can improve recovery for individuals newly diagnosed with breast cancer who have not yet started treatment. Participants will consume only provided meals for four weeks before surgery to assess the diet's impact on body health, inflammation, and surgical recovery. It suits post-menopausal women with stage I-III breast cancer, a BMI between 28-35, and a diet of fewer than five servings of fruits and vegetables daily. As an unphased trial, this study offers a unique opportunity to contribute to understanding the potential benefits of dietary changes on cancer recovery.

Research has shown that the Mediterranean diet is generally safe and easy to follow. This diet emphasizes fruits, vegetables, whole grains, and healthy fats like olive oil. Known for its heart-health benefits, it is often recommended for this reason.

Regarding safety, no major side effects are typically reported. Many people worldwide incorporate this diet into their daily lives. This trial is a pilot study, where researchers are examining how this diet specifically affects breast cancer patients. Since the study involves a diet rather than a new drug or treatment, the safety risks remain low.

The Mediterranean Diet is unique because it focuses on enhancing overall health through nutrition, rather than relying on traditional medical interventions like chemotherapy or hormone therapy for breast cancer. This diet is rich in fruits, vegetables, whole grains, and healthy fats, which are known for their anti-inflammatory and antioxidant properties. Researchers are excited about this approach because it offers a holistic, non-invasive way to potentially improve treatment outcomes and quality of life for breast cancer patients without the side effects often associated with conventional treatments.

Research has shown that the Mediterranean diet might help lower the risk of breast cancer. One study found that women who followed this diet had a 62% lower risk of developing serious breast cancer. Another long-term study demonstrated up to a 77% reduction in breast cancer risk for those who adhered to this eating pattern. The Mediterranean diet includes plenty of fruits, vegetables, olive oil, and whole grains. It might also enhance treatment effectiveness and reduce the likelihood of cancer recurrence. Overall, this diet is linked to numerous health benefits, making it a promising choice for those aiming to lower their breast cancer risk. Participants in this trial will receive all meals and snacks for 4 weeks, following a standardized Mediterranean diet meal plan.⁶⁷⁸⁹¹⁰