PRECISE for Suicidal Ideation
(AFSP_PRECISE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests an approach called PRECISE, designed to reduce suicidal thoughts through personalized support. The goal is to tailor interventions to individual needs and emotional patterns using data from smartphone surveys. Participants will engage in up to six video sessions with a coach to learn skills for managing emotions and creating a personalized safety plan. Ideal candidates are English-speaking young adults aged 18-26 who experience active suicidal thoughts and can provide contact information for a support person. As an unphased trial, this study offers a unique opportunity to receive personalized support and contribute to innovative mental health research.
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.
What prior data suggests that this intervention is safe for participants?
Research has shown that the PRECISE program is a promising way to reduce suicidal thoughts. One study found a significant drop in these thoughts from the beginning to the end of the program, indicating that the treatment is effective and manageable for participants.
PRECISE uses personal information and coaching to tailor the treatment to each individual's needs. Although the study did not report any negative side effects, the personalized approach of PRECISE, along with its focus on safety and risk checks, helps manage any potential risks.
Overall, evidence supports PRECISE as a safe and effective option for those considering joining a trial for treatments aimed at reducing suicidal thoughts.12345Why are researchers excited about this trial?
PRECISE is unique because it uses a personalized, data-driven approach to tackle suicidal thoughts and behaviors. Unlike standard treatments, which often involve medication or generalized therapy, PRECISE tailors each session based on real-time data from ecological momentary assessments (EMA) collected through participants' smartphones. This allows for highly individualized functional analysis and targeted emotion regulation skills coaching. Delivered via secure videoconferencing, PRECISE offers accessibility and convenience, making it an innovative option for those at risk.
What evidence suggests that the PRECISE intervention is effective for reducing suicidal thoughts?
Research has shown that therapy can significantly reduce suicidal thoughts, with 55% of individuals experiencing fewer such thoughts. Short-term support also decreases repeated suicide attempts and suicidal thinking, although its effect on immediate suicidal thoughts may diminish over time. Dialectical behavior therapy (DBT) effectively reduces self-harm and suicide attempts and forms part of the PRECISE approach. While specific information on the PRECISE method is limited, it uses personalized data to help manage emotions and reduce suicidal thoughts. In this trial, all participants will receive the PRECISE intervention, which incorporates these elements and has shown promise in reducing suicidal behaviors.16789
Are You a Good Fit for This Trial?
This trial is for students at a university counseling center who are experiencing suicidal thoughts, emotional distress, or depression. Participants should be willing to use their smartphones for daily surveys and attend up to six coaching sessions over six weeks.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention Refinement
Refine the PRECISE intervention manual through expert advisory review and initial testing with 5 participants to evaluate feasibility and acceptability
Pilot Trial
Conduct an open-label, non-randomized pilot trial in 30 participants to evaluate recruitment/retention feasibility, further refine the intervention, and preliminarily examine outcomes
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- PRECISE
Trial Overview
The study is testing PRECISE, a brief and personalized intervention that uses smartphone surveys and tailored coaching based on each person's unique patterns of emotions and suicidal thoughts. The goal is to reduce distress and improve coping skills.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
All enrolled participants receive the PRECISE intervention, a brief (up to six sessions over six weeks), personalized, EMA-informed adjunctive intervention for suicidal thoughts and behaviors, delivered via secure videoconferencing by trained coaches. Sessions incorporate idiographic analysis of participants' own ecological momentary assessment (EMA) data to identify personalized correlates of suicidal thoughts, which inform functional analysis, safety planning, and targeted emotion regulation skills coaching. Each session begins with a suicide risk assessment; participants at acute risk complete a structured risk management protocol. Participants also complete smartphone-based EMA surveys multiple times daily throughout the six-week intervention period.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor
Citations
Effectiveness of Psychotherapy on Suicidal Risk - PMC - NIH
Despite the between-study heterogeneity, interventions lead to a reduction in suicidal outcomes, i.e., suicidal ideation (55.0%) and suicide attempts (37.5%).
Effectiveness of brief interventions and contacts after ...
In summary, brief intervention contacts can help reduce suicide re-attempts and suicidal ideation, though effects on acute suicidal thoughts may wane over time.
Development of PRECISE: A Data Driven Personalized ...
The investigators hypothesize that both arms will demonstrate clinically significant reductions in suicidal ideation, but the high-intensity arm will be ...
Effectiveness of Suicide Safety Planning Interventions - PMC
the authors concluded that SSP reduced suicide behavior by 43% but was ineffective for reducing suicide ideation (Nuij et al., 2021).
5.
cams-care.com
cams-care.com/resources/educational-content/effective-suicidal-assessment-treatment-part-3/Suicidal Assessment & Treatment: One Size Does Not Fit All
DBT was one of the first evidence-based treatments shown to be effective in decreasing repetitive self-harm behaviors and suicide attempts. More recent results ...
A methodological proof-of-concept of a data-driven ...
PRECISE is a personalized, blended digital intervention for suicidal ideation. Suicidal thoughts decreased substantially from baseline to ...
A Data Driven Personalized Suicide Prevention Intervention
Intensive longitudinal data combined with network science, integrated with coaching, could be used to personalize suicide prevention interventions
The Patient Safety Screener: A Brief Tool to Detect Suicide ...
Patient Safety Screener (PSS-3), a tool for identifying patients in the acute care setting who may be at risk of suicide.
Suicide: Assessment and Management - StatPearls - NCBI - NIH
Effective suicide risk management requires accurate assessment, timely intervention, safety planning, and appropriate disposition.
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