At-home Paracentesis for Malignant Ascites

(Paracentesis Trial)

This trial aims to observe changes in symptoms when women with cancer-related fluid buildup in the abdomen (malignant ascites) perform paracentesis at home. Paracentesis involves draining excess fluid from the abdomen to relieve discomfort. Women who have undergone a similar procedure in a clinic and experience symptoms from this fluid buildup might be suitable candidates for the trial. The study seeks to determine if performing the procedure at home can effectively ease symptoms. As an unphased trial, it offers participants the chance to contribute to research that could enhance home-based care for others in the future.

The trial does not specify if you need to stop taking your current medications. However, if you are on anticoagulant therapy (blood thinners), you may need to pause it before the procedure, depending on the investigator's opinion.

Research has shown that performing paracentesis at home safely manages malignant ascites, a condition where fluid accumulates in the abdomen due to cancer. Studies have found that patients handle this procedure well in a home setting.

For example, several studies have found that home-based paracentesis is not only safe but also effective and convenient for patients requiring comfort care. One study noted that patients could undergo this procedure safely and effectively without hospital visits. Another study confirmed that this method works well for those with recurring fluid buildup.

Researchers are excited about at-home paracentesis for malignant ascites because it offers a new level of convenience and comfort for patients. Unlike traditional paracentesis, which requires hospital visits, this method allows the procedure to be performed at home, reducing the need for frequent hospital trips and potentially lowering healthcare costs. This new approach could significantly improve the quality of life for patients by minimizing travel and wait times, making it a promising alternative to standard care.

Research has shown that performing paracentesis at home effectively manages malignant ascites, a condition where fluid accumulates in the abdomen due to cancer. One study found that draining this fluid at home is safe and helps many patients manage their symptoms easily. Another study concluded that this method is not only safe but also a cost-effective way to relieve discomfort. In 64% to 100% of cases, patients experienced symptom relief, meaning most felt better. Additionally, even small amounts of fluid removal at home can significantly reduce abdominal swelling in terminally ill cancer patients. Overall, the evidence supports at-home paracentesis as a promising option for managing symptoms in patients with malignant ascites.¹²³⁶⁷