176 Participants Needed

Early Catheter Removal After Colorectal Surgery

Recruiting at 1 trial location
SK
Overseen BySarah Koller, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Southern California
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines the optimal timing for removing a urinary catheter after colorectal surgery. The researchers aim to determine if removing the catheter one day after surgery is as safe as waiting three days. This is crucial because longer catheter use can lead to infections and extended hospital stays. Individuals who have planned surgeries for rectal cancer or certain bowel diseases may be suitable for the trial, particularly if they have no history of urinary retention. Participants will be randomly assigned to have their catheter removed on either day one or day three after surgery to compare outcomes such as urinary retention and hospital stay length. As an unphased trial, this study allows participants to contribute to significant research that could enhance recovery experiences for future patients.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that early catheter removal is safe after colorectal surgery?

Research has shown that removing a urinary catheter the day after colorectal surgery is usually safe for patients. One study found that early removal can lower the risk of urinary tract infections compared to keeping it in for three days. Another study found that early removal did not increase the risk of urinary retention, a condition where the bladder can't empty properly. However, some evidence suggests a slightly higher chance of urinary retention with early removal, but this risk is often manageable. Overall, early catheter removal is well-tolerated and can lead to shorter hospital stays.12345

Why are researchers excited about this trial?

Researchers are excited about the early removal of urinary catheters after colorectal surgery because it could significantly reduce the risk of urinary tract infections (UTIs). Traditionally, catheters are left in for several days post-surgery to aid recovery, but this can increase infection risk. This trial explores removing the catheter just one day after surgery, which might lead to faster recovery times and fewer complications for patients. By potentially reducing hospital stays and improving overall patient comfort, this approach could represent a meaningful advancement in post-surgical care.

What evidence suggests that early catheter removal is effective for reducing urinary retention after colorectal surgery?

This trial will compare the effects of removing urinary catheters on postoperative day 1 versus day 3 after colorectal surgery. Research has shown that removing urinary catheters the day after surgery is as safe as leaving them in for three days. Studies have found that early removal does not increase the risk of urinary retention, where the bladder can't empty properly. In fact, removing the catheter sooner might reduce the chance of developing a urinary tract infection (UTI). One study found a significantly lower risk of UTIs with early removal. Overall, early removal appears to be a safe and effective approach without additional complications.12678

Are You a Good Fit for This Trial?

Adults over 18 undergoing elective colorectal surgery for rectal cancer or inflammatory bowel disease, who can sign consent. It's open to all surgical approaches and includes those with prior chemo/radiation treatments. Excludes emergency surgeries, combined major procedures, previous urinary issues like retention or injuries during surgery.

Inclusion Criteria

My health is good to moderate, as rated by an anesthesiologist.
I am scheduled for or have had surgery for rectal cancer or inflammatory bowel disease.
Ability to understand and the willingness to sign a written informed consent
See 2 more

Exclusion Criteria

Patients with chronic indwelling Foley catheterization or suprapubic catheterization
I have had trouble urinating after a past surgery or catheter removal.
I need a long-term urinary catheter after surgery for reasons other than not being able to urinate.
See 8 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Perioperative period

Treatment

Participants undergo total mesorectal excision surgery with urinary catheterization. Randomized to catheter removal on postoperative day 1 or 3.

1-3 days
Inpatient hospital stay

Follow-up

Participants are monitored for urinary retention, urinary tract infections, and length of hospital stay until discharge.

Up to day of discharge

What Are the Treatments Tested in This Trial?

Interventions

  • Urinary catheter removal on postoperative day 1
  • Urinary catheter removal on postoperative day 3

Trial Overview

The study is testing if removing the urinary catheter on day 1 after colorectal surgery is as safe as the standard practice of removal on day 3. The goal is to see if early removal reduces urinary infections and hospital stays without increasing the risk of urine retention.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Urinary catheter removal on postoperative day 1Experimental Treatment1 Intervention
Group II: Urinary catheter removal on postoperative day 3Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Southern California

Lead Sponsor

Trials
956
Recruited
1,609,000+

Citations

1.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/30192326/

Early Urinary Catheter Removal Following Pelvic ...

This study aims to compare the incidence of urinary retention following early catheter removal on postoperative day 1 vs standard catheter removal on day 3.

Comparing Immediate Removal and Postoperative 1 Day ...

Comparative Analysis of Clinical and Patient-Reported Outcomes: Immediate Versus Postoperative Day 1 Removal of Urinary Catheter After Colorectal Cancer Surgery ...

Early urinary catheter removal in patients undergoing rectal ...

Early urinary catheter removal on the first postoperative day was safe in both groups. The use of the oral α-antagonist silodosin did not ...

Early post-operative removal of urethral catheter in patients ...

We examine the timing of UC removal in colorectal surgery with epidural analgesia. This randomised clinical trial compares early removal with standard timing.

Early urinary catheter removal after rectal surgery - PMC - NIH

Early catheter removal resulted in a significantly reduced risk of UTI compared with late removal.

Early urinary catheter removal in patients undergoing rectal ...

Early urinary catheter removal on the first postoperative day was safe in both groups. The use of the oral α-antagonist silodosin did not ...

Timing of urinary catheter removal after colorectal surgery ...

Early removal of urinary catheters after pelvic colorectal surgery is associated with increased risk of urinary retention. •. Leaving urinary ...

Early urinary catheter removal after rectal surgery

Early catheter removal was superior for UTI (RD −11 (95 per cent c.i. −17 to −4) per cent; P = 0·001). Results for length of stay were mixed. There were ...