RO7890597 for Healthy Volunteers
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will evaluate the safety, pharmacokinetics (PK), and activity of single and multiple doses of RO7890597 compared with placebo in healthy volunteers. The study includes single ascending dose (SAD) stage, multiple ascending dose (MAD) stage, food-effect and proton pump inhibitor (PPI) stages, and a supplemental drug-drug interaction (DDI) stage.
Who Is on the Research Team?
Clinical Trials
Principal Investigator
Genentech, Inc.
Are You a Good Fit for This Trial?
This trial is for healthy adults who do not have any significant medical conditions. Participants should not be taking medications or have health issues that could affect the study results.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- RO7890597
Trial Overview
The study tests different doses of a new drug called RO7890597, comparing it to placebo in healthy volunteers. It also looks at how food and other drugs like rabeprazole (a stomach acid reducer) and itraconazole (an antifungal) affect RO7890597.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Participants will receive a single or multiple doses of RO7890597 alone, or with rabeprazole or itraconazole.
Participants will receive single or multiple doses of matching placebo.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Genentech, Inc.
Lead Sponsor
Ashley Magargee
Genentech, Inc.
Chief Executive Officer since 2024
MBA from Harvard University, BA from Princeton University
Levi Garraway
Genentech, Inc.
Chief Medical Officer since 2021
MD, PhD
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