Prehabilitation Exercise Program for Frailty
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a special exercise program can help frail adults recover better from surgery. The program combines strength training with advice to "sit less, move more" to reduce complications and speed up recovery. Adults aged 50 or older who feel physically vulnerable or frail and are scheduled for elective surgery might be suitable candidates. Participants will either follow this new exercise plan or continue with standard care. The goal is to make recovery smoother and lessen the burden on healthcare.
As an unphased trial, this study offers a unique opportunity to contribute to innovative recovery strategies and potentially benefit from personalized exercise guidance.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this prehabilitation exercise program is safe for frail patients?
Research has shown that exercise programs, like the one being studied, are generally safe for older adults. Strength training, in particular, has proven effective and safe for enhancing physical strength and mental health. Studies indicate that even minimal resistance training can help manage frailty without major risks.
Physical activity plays a crucial role in improving frailty in older adults. It not only builds muscle strength but also reduces the risk of falls and related health issues.
These studies do not report any severe side effects, suggesting that such exercise programs are well-tolerated. Therefore, the program is likely safe for frail individuals, but it remains important to follow healthcare providers' advice during participation.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it combines neuromuscular exercise with a "sit less, move more" approach to tackle frailty in older adults. Unlike traditional treatments that may focus solely on physical therapy, this program emphasizes both strength training and reducing sedentary behavior. The use of personalized coaching and a Fitbit activity monitor helps participants actively engage with their daily routines, making it easier to incorporate light-intensity activities throughout the day. This dual approach aims to improve overall mobility and independence, offering a comprehensive solution that goes beyond standard rehabilitation practices.
What evidence suggests that this prehabilitation exercise program is effective for frailty?
This trial will evaluate a combined neuromuscular exercise training and "sit less, move more" program for frailty. Research has shown that exercise can significantly help manage frailty. Studies have found that exercise improves muscle strength and balance in older adults, which are crucial for reducing frailty. Strength training, in particular, can lessen the severity of frailty and related issues like muscle loss. Programs encouraging people to "sit less, move more" can increase daily activity and lower health risks associated with excessive sitting. Evidence suggests that even small amounts of resistance training can effectively improve strength and overall health in frail older adults. Participants in this trial will receive either the experimental exercise program or standard care.26789
Who Is on the Research Team?
Naheed Rajabali, MD
Principal Investigator
Alberta Health services
Victor Ezeugwu, PhD
Principal Investigator
University of Alberta
Are You a Good Fit for This Trial?
This trial is for people aged 50 or older who are scheduled for elective surgery and have been identified as vulnerable or mildly/moderately frail based on a clinical scale. They must be able to walk, with or without aids. Those with unstable medical conditions that limit exercise tolerance cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Prehabilitation
Participants undergo a 12-week prehabilitation program combining neuromuscular strength training and sedentary behavior intervention
Surgery and Immediate Postoperative Care
Participants undergo elective surgery and receive immediate postoperative care
Follow-up
Participants are monitored for safety and effectiveness after surgery, including assessments of gait speed, physical activity, and other health metrics
What Are the Treatments Tested in This Trial?
Interventions
- Combined neuromuscular exercise training and 'sit less, move more' program
Trial Overview
The study tests if a pre-surgery program combining strength training exercises and activities aimed at reducing sitting time can decrease complications, shorten hospital stays, and speed up recovery in patients undergoing elective surgery.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Neuromuscular strength training: The experimental group will receive up to 24 sessions of neuromuscular strength training led by a physical therapist with expertise in geriatrics and movement behaviors. The program includes exercises such as pelvic lifts, lunges, step-ups, squats, and sit-stands. The difficulty level will progressively increase using techniques like manual resistance, dumbbells, and unstable surfaces. Sedentary behavior intervention: The experimental group will also undergo a sedentary behavior intervention based on social cognitive theory. It involves weekly coaching sessions to enhance self-efficacy in reducing sedentary time and increasing light-intensity activity throughout the day. Participants will be provided with a wrist-worn Fitbit activity monitor for daily feedback and to track adherence to the intervention. The aim is to encourage participants to "sit less and move more" throughout their waking hours.
The control group will receive standard of care that is provided as part of the perioperative surgical procedure and subsequent rehabilitation.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alberta
Lead Sponsor
Victor Ezeugwu
Lead Sponsor
Royal Alexandra Hospital
Collaborator
Citations
Mind–body training outperforms other physical activities in ...
In our analysis, Mind–body training significantly improved frailty (SMD = −0.71, 95% CI: −1.22 ~ −0.21) and QoL (SMD = 1.02, 95% CI: −0.43 ~ ...
Physical activity and exercise: Strategies to manage frailty
Exercise reduces age-related oxidative damage and chronic inflammation, e in muscle strength may lead to reduced pulmonary function, low physical performance, ...
a systematic review and Bayesian network meta-analysis
Exercise interventions can effectively improve muscle strength and balance function in pre-frail older adults, with elastic band exercise and ...
Chronic Effects of Different Intensities of Power Training on ...
PT performed at low-to-moderate intensities induces similar power gains compared to high-intensity PT (70–80% of 1RM) in older adults.
Benefits of Resistance Training in Early and Late Stages ...
Generally, exercise interventions can decrease the prevalence of frailty and sarcopenia and are also effective in reducing the severity of these syndromes
Heavy Strength Training in Older Adults - PMC
However, taken together, the data suggest that heavy‐very heavy strength training results in a lower cardiovascular risk than strength training ...
7.
frontiersin.org
frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2025.1542188/fullLow-volume resistance training: a feasible, cost-effective ...
Our results indicate that even a low-volume resistance training program can yield meaningful benefits for managing frailty, sarcopenia and fall prevalence.
Growing Stronger - Strength Training for Older Adults
Feeling physically strong also promotes mental and emotional health. Strength training exercises are easy to learn, and have been proven safe and effective ...
9.
news-medical.net
news-medical.net/news/20250720/Mind-body-exercise-best-reduces-frailty-and-boosts-quality-of-life-in-older-adults-study-finds.aspxMind-body exercise best reduces frailty and boosts quality ...
Overall, mind-body training was considered to be 81% more effective in ameliorating frailty in older adults than all other interventions. Mind- ...
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