Learn More About Power

Why We Started Power

We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

Bask
Bask GillCEO at Power
Learn More About Trials
How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
1045 Sansome St, Suite 321, San Francisco, CA
hello@withpower.com(415) 900-4227
About UsClinical Trials by ConditionAll Clinical TrialsWork With Us
1
Directories
Conditions
Cities
States
Popular Categories
Depression & Anxiety
Neurology
Psychiatry
Pain
Metabolism
Treatments
Locations
Florida
New Jersey
North Carolina
Texas
Ohio
California
Pennsylvania
Kentucky
New York
Indiana
Psychology Related
Depression
Schizophrenia
Anxiety
PTSD
ADHD
Autism
Bipolar Disorder
Addiction
OCD
Eating Disorder
Treatments
Psilocybin
IVF
Dental Implant
Weight Loss
Smoking
Platelet-Rich Plasma
Testosterone
Saxenda
Melatonin
Entresto
Cities
Saint Louis
Columbus
Portland
Ann Arbor
Aurora
Salt Lake City
Rochester
Birmingham
Detroit
New Haven
Terms of Service·Privacy Policy·Cookies
Cookies & Data Use Policy

At Power, we believe in using data responsibly to help you find the right clinical trials — without compromising your privacy. This page explains how we use cookies and personal data across www.withpower.com.

Before You Create a Profile

When you browse Power's website, you're opting in to our use of cookies. Cookies are used to improve your experience and help us understand how the site is used so that we can make improvements for you in the future. Specifically, we use cookies to:

Personalize Your Experience

We use cookies to customize your visit based on basic information like your general location (determined by your IP address). This allows us to:

  • Show you clinical trials that are geographically relevant to you
  • Tailor search results to match the conditions or keywords you've explored before
  • Pre-fill certain fields or remember your previous searches, so you don't have to repeat them

Save Your Preferences

We remember what you interact with during your visit — for example:

  • The conditions you search for
  • Whether you prefer certain types of studies (e.g., paid trials, trials for a specific age group)
  • Your sorting or filtering preferences when browsing trials

This helps us make your experience more efficient and personalized the next time you visit.

Understand How the Site Is Used

Cookies help us collect anonymous usage data so we can make Power better. We use these insights to:

  • Monitor how users move through the site — for example, which pages get the most traffic and where users tend to exit
  • Track how long visitors stay on each page and whether they find what they’re looking for
  • Identify points of friction or confusion so we can improve usability
  • Test design changes (like different page layouts or buttons) and measure which version performs better
  • Detect and fix bugs or slow-loading pages to maintain site reliability

These analytics are aggregated and do not include personal identifiers. We use tools like Google Analytics to process this data, but we don't use it to target ads or sell your information.

We do not:

  • Sell or share your personal data with advertisers
  • Use your behavior on our site to target you with third-party ads

All cookie use is designed to support your experience on Power — never to track you across the internet or monetize your information.

After You Create a Profile

When you sign up for a Power account, you agree to our Privacy Policy and Terms of Service. Creating a profile allows us to better serve you by tailoring the platform to your specific needs.

Once you create a profile:

  • We may collect additional information about your health and clinical interests to help us match you to the most relevant studies.
  • We continue to use cookies to remember your session, keep you logged in, and personalize your dashboard.
  • You have full control — you can delete your profile at any time, and we'll remove your personal data in accordance with our privacy practices.

We use your data solely to fulfill our mission: helping you find clinical trials that could be a fit — not for advertising or resale.

·Security
Condition
Suggested Conditions
  • Anxiety
  • Depression
  • Alzheimer's Disease
  • Weight Loss
  • Heart Disease
  • Cancer
  • Asthma
Location

    Osteoarthritis

    Boston, MA

    Search
    Osteoarthritis
    Boston, MA
    Show Map
    Map View
    Boston, MA

    Popular Searches

    By Condition

    Depression Clinical Trials in Massachusetts

    Anxiety Clinical Trials in Massachusetts

    Schizophrenia Clinical Trials in Massachusetts

    ADHD Clinical Trials in Massachusetts

    Bipolar Disorder Clinical Trials in Massachusetts

    Multiple Sclerosis Clinical Trials in Massachusetts

    Autism Clinical Trials in Massachusetts

    Treatment Resistant Depression Clinical Trials in Massachusetts

    Borderline Personality Disorder Clinical Trials in Massachusetts

    Social Anxiety Disorder Clinical Trials in Massachusetts

    Parkinson's Disease Clinical Trials in Massachusetts

    Alzheimer's Disease Clinical Trials in Massachusetts

    By Location

    Clinical Trials near Boston, MA

    Clinical Trials near Worcester, MA

    Clinical Trials near Springfield, MA

    Clinical Trials near Burlington, MA

    Clinical Trials near Fall River, MA

    Clinical Trials near Cambridge, MA

    Clinical Trials near North Dartmouth, MA

    Clinical Trials near Newton, MA

    Clinical Trials near Waltham, MA

    Clinical Trials near Watertown, MA

    Clinical Trials near Belmont, MA

    Clinical Trials near Brockton, MA

    Other People Viewed

    By Subject

    Top Clinical Trials near Boston, MA

    Top Clinical Trials near Boston, MA

    102 Arthritis Trials near Boston, MA

    Top Depression Clinical Trials near Boston, MA

    Top Osteoporosis Clinical Trials near Boston, MA

    Top Weight Loss Clinical Trials near Boston, MA

    Top Colorectal Cancer Clinical Trials near Boston, MA

    Top Breast Cancer Clinical Trials near Boston, MA

    Top Lung Cancer Clinical Trials near Boston, MA

    Top Prostate Cancer Clinical Trials near Boston, MA

    Top Clinical Trials near Jamaica Plain, MA

    Top Knee Osteoarthritis Clinical Trials

    By Trial

    Gait Retraining for Knee Osteoarthritis

    Fat-Derived Cell Therapy for Osteoarthritis

    Joint Mobilization and Exercise for Osteoarthritis

    tDCS + Mindfulness Meditation for Osteoarthritis

    Knee Artery Embolization for Osteoarthritis

    Vitamin K for Knee Osteoarthritis

    Exercise + Duloxetine for Knee Osteoarthritis

    Total Knee Replacement for Osteoarthritis

    OA-SYS for Osteoarthritis

    Ibuprofen & Acetaminophen vs Oxycodone for Postoperative Pain

    Postoperative Hip Precautions for Osteoarthritis

    Categorized Physical Therapy for Hip Pain

    Related Searches

    Top Osteoarthritis Clinical Trials near Irvine, CA

    Top Osteoarthritis Clinical Trials near Los Angeles, CA

    Top Osteoarthritis Clinical Trials near Orlando, FL

    Top Osteoarthritis Clinical Trials near Sacramento, CA

    Top Osteoarthritis Clinical Trials near San Diego, CA

    Top Parkinsons-disease Clinical Trials near Boston, MA

    Reducing Vaccine Hesitancy for COVID-19

    Psilocybin for Headaches

    Gotistobart vs Chemotherapy for Lung Cancer

    Oral Azacitidine for Leukemia

    Deep Brain Stimulation for Epilepsy

    Hybrid Argon Plasma Coagulation + Endoscopic Sleeve Gastroplasty for Obesity

    Search Clinical Trials
    Conditions
    Suggestions
    • Anxiety
    • Depression
    • Alzheimer's Disease
    • Weight Loss
    • Heart Disease
    • Cancer
    • Asthma
    Locations
    Suggestions
      Treatment Type
      Suggestions
      • Cognitive Behavioral Therapy
      • Medication Management
      • Group Therapy
      • Psychotherapy
      • Mindfulness-Based Therapy
      • Exposure Therapy

      Trial Phase

      Trial Status

      Paid Participation

      Filters

      0

      Suggestions
      • Cognitive Behavioral Therapy
      • Medication Management
      • Group Therapy
      • Psychotherapy
      • Mindfulness-Based Therapy
      • Exposure Therapy

      Paid Participation

      Trial Status

      Trial Phase

      Clear All
      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?

      135 Osteoarthritis Trials near Boston, MA

      Power is an online platform that helps thousands of Osteoarthritis patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.

      Learn More About Power
      No Placebo
      Highly Paid
      Stay on Current Meds
      Pivotal Trials (Near Approval)
      Breakthrough Medication

      Powered Exoskeleton for Knee Osteoarthritis

      The Bronx, New York
      The purpose of this study is to evaluate in-laboratory mobility outcomes, pain perception, and user satisfaction with the Keeogo , a robotic exoskeleton for providing assistance on knees during stand and swing for a population with impaired mobility, as compare with standard knee braces. The investigators hypothesize that participants could have improved performance outcomes on walk test, timed up and go test, stair test, pick up penny from floor test, and the Short Physical Performance Battery (SPPB) when using the Keeogo as compared with their prescribed knee braces.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Neurological Paralysis, Fixed Contractures, Cardiovascular Disorders, Others

      16 Participants Needed

      Surgical Navigation System for Osteoarthritis

      Lake Success, New York
      The purpose of this research is to gather clinical and radiographic (X-ray) information about EMPHASYS™ acetabular shell (also called a hip 'cup') placement in total hip replacement surgery using a non-invasive surgical navigation system called VELYS™ hip navigation system with CUPTIMIZE™ Advanced Hip-Spine Analysis software. Data collected in this study will be compared with data collected from implantations using different cup positioning instrumentation and techniques to assess performance.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:21+

      Key Eligibility Criteria

      Disqualifiers:Infection, Osteoporosis, Pregnancy, Amputation, Others
      Must Not Be Taking:Muscular Disorder Medications

      118 Participants Needed

      Insignia Hip Stem for Hip Osteoarthritis

      Great Neck, New York
      This trial is testing the safety and effectiveness of the Insignia™ Hip Stem, an artificial hip joint, in patients needing hip replacement surgery. It aims to see how well it works and how safe it is over a long period.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Pregnancy, Infection, Neuromuscular Disorder, Others
      Must Not Be Taking:Steroids

      313 Participants Needed

      Stem Cell Treatment for Knee Osteoarthritis

      New York, New York
      This trial is testing a new treatment that uses cells from a patient's own fat to help repair knee damage in people with knee osteoarthritis. The cells are injected into the knee to reduce pain and improve joint function. This type of therapy has been increasingly studied and used for treating knee osteoarthritis due to its potential to reduce pain and improve joint function.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2, 3

      Key Eligibility Criteria

      Disqualifiers:BMI > 35, Cancer, Heart Diseases, Autoimmune Diseases, Inflammatory Joint Disorders, Others
      Must Not Be Taking:Anti-inflammatories, Oral Steroids

      140 Participants Needed

      Moving Well for Osteoarthritis

      New York, New York
      The purpose of this study is to assess the efficacy of a behavioral intervention, Moving Well, in improving levels of anxiety and depression for patients undergoing total knee arthroplasty (TKA).
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:50+

      Key Eligibility Criteria

      Disqualifiers:Non-English Speakers, Unable To Exercise, RA, Others

      79 Participants Needed

      Episealer Knee System vs Microfracture Surgery for Osteoarthritis

      New York, New York
      This trial is testing a knee implant called the Episealer Knee System on patients with specific knee damage causing pain or disability. The implants aim to repair the damaged areas, improving knee function and reducing pain.

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:30 - 70

      Key Eligibility Criteria

      Disqualifiers:Obesity, Osteoporosis, Rheumatoid Arthritis, Others
      Must Not Be Taking:Corticosteroids, Immunosuppressants, Immunostimulants, Others

      13 Participants Needed

      Robotic-Assisted Knee Replacement for Osteoarthritis

      New York, New York
      Total knee replacement surgery is a conventional approach to alleviating the pain and lack of function resulting from arthritis of the knee. While conventional knee replacement surgery is highly successful, incidences of improperly installed replacement parts are not uncommon. To improve outcomes, robotic-assisted total knee replacement surgery has recently become available, and has been shown to be extremely effective for partial knee replacement surgery. However, further research is needed to determine if this same technology can be equally effective for total knee replacement surgery. The present study will evaluate outcomes of robotic-assisted versus conventional total knee replacement surgery in patients between 40 and 85 years old with end stage arthritis of the knee. Other than surgical technique, patients will receive the same operative care and knee replacement implants. In addition to standard x-rays, subjects will be asked to complete several short-term clinical and functional tests and questionnaires to determine outcomes of their surgery.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:40 - 85

      Key Eligibility Criteria

      Disqualifiers:Inflammatory Arthropathy, Prior Knee Surgery, Osteotomy, Others

      86 Participants Needed

      PRP Injections for Shoulder Osteoarthritis

      New York, New York
      The glenohumeral joint is the third most common large joint to be affected by OA. Conservative treatments include physical activity, corticosteroid injections, and medications. PRP is an emerging treatment that has shown efficacy in different musculoskeletal conditions. The use of PRP for glenohumeral OA has been described sparingly in the literature but has shown efficacy in a couple studies and case reports. However, all of the previous studies investigating PRP for glenohumeral OA have focused on low-dose PRP preparations (\~3X), and none have compared PRP treatment to saline treatment. This study aims to compare outcomes following single injections of low-dose PRP, high-dose PRP, or saline in patients with glenohumeral osteoarthritis.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 4

      Key Eligibility Criteria

      Disqualifiers:Uncontrolled Diabetes, HIV, Others
      Must Not Be Taking:Plavix, Steroids, Hyaluronic Acid

      135 Participants Needed

      Physical Therapy vs Remote Exercise for Osteoarthritis

      New York, New York
      The purpose of this clinical study is to demonstrate that after six weeks of at home exercise, 3 times per week with SimpleTherapy, participants with clinical indications of knee OA will on average have improved outcomes noninferior than traditionally prescribed physical therapy regimens.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Cognitive Impairment, Knee Arthroplasty, Inflammatory Arthritis, Neuropathies, Others

      220 Participants Needed

      IV Hydrocortisone for Post-Knee Replacement Recovery

      New York, New York
      In this study, total knee replacement patients will be determined to be stiff or non-stiff preoperatively. Stiffness designation is determined by preoperative range of motion (if flexion is \< 100 degrees, or extension lag is \> 10 degrees). The stiff and non-stiff groups will both be randomized to two groups to receive either intravenous hydrocortisone or a placebo at 3 intervals postoperatively. Patients will be followed up with in hospital and via the phone on postoperative day (POD) 1 and 2, as well as 6 weeks, 6 months, 1 year, and 2 years postoperatively. Patients will also have blood drawn preoperatively in the OR, on POD1, at their 6 week followup, and at their 1 and 2 year follow ups. This blood will be processed and analyzed.

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 4

      Key Eligibility Criteria

      Disqualifiers:Rheumatic, Autoimmune, Immunodeficiency, Obesity, Others
      Must Not Be Taking:Oral Steroids, Insulin

      132 Participants Needed

      PRP Injections for ACL Injury

      New York, New York
      The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury. This RCT has been powered based on the questionnaire KOOS Jr. but it is considered a 'pilot study' in terms of the lab analysis proposed.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 3
      Age:14 - 50

      Key Eligibility Criteria

      Disqualifiers:Prior ACL Reconstruction, Cartilage Repair, Others
      Must Not Be Taking:Steroids, Hyaluronic Acid, PRP

      56 Participants Needed

      Cannabidiol for Knee Surgery Pain

      New York, New York
      In light of the opioid epidemic and evidence suggesting that cannabis may be opioid-sparing, we are in a unique position to conduct a novel, high-impact study that would set the stage for future RCTs examining the effects of a nonintoxicating and nonaddictive cannabinoid in an orthopedic patient population. Epidiolex®, an oral cannabidiol (CBD) solution, is the first ever cannabis-derived medication to be approved by the Food \& Drug Administration. Our aim is to conduct a pilot study using a placebo oral solution, 400mg and 800mg Epidiolex® to gather data on its effects on patients undergoing bilateral total knee arthroplasty (BTKA). We will be estimating whether Epidiolex® is associated with minimal opioid use and adequate analgesia. We will also assess its tolerability, pharmacokinetics, and effects on inflammatory markers in the perioperative setting.

      Trial Details

      Trial Status:Active Not Recruiting

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      37 Participants Needed

      TG-C for Knee Osteoarthritis

      New York, New York
      This trial tests TG-C, an injection into the knee, for people with moderate to severe knee osteoarthritis. It aims to see if TG-C can reduce pain and improve knee function by potentially altering the disease. The study will monitor patients for safety and effectiveness over time. TG-C has been previously studied for its potential to improve knee joint function and reduce pain in osteoarthritis patients.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3
      Age:40+

      Key Eligibility Criteria

      Disqualifiers:Rheumatoid Arthritis, Diabetes, Cancer, Others
      Must Not Be Taking:NSAIDs, Steroids, Biologics, Narcotics

      531 Participants Needed

      Methylprednisolone for Osteoarthritis

      New York, New York
      This study aims to evaluate the effectiveness of an oral methylprednisolone taper in reducing postoperative pain, opioid consumption, and nausea following primary total knee arthroplasty (TKA).
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 1

      Key Eligibility Criteria

      Disqualifiers:Liver Disease, Renal Disease, Diabetes, Others
      Must Not Be Taking:Corticosteroids, Opiates

      130 Participants Needed

      Wharton's Jelly Injections for Knee Osteoarthritis

      New York, New York
      This is a Pilot Study which is randomized, prospective, open label, dose escalation, non-controlled evaluating safety and feasibility of intra-articular Wharton's Jelly (WJ) allograft will be evaluated in patients suffering with knee osteoarthritis. The participants will be randomized to one of three dosing treatment arms that will consist of one intra-articular knee injection containing either low dose, medium dose or high dose WJ allograft tissue.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Early Phase 1
      Age:30+

      Key Eligibility Criteria

      Disqualifiers:Autoimmune Disorders, Carcinoma, Knee Infection, Others
      Must Not Be Taking:NSAIDs, Anticoagulants, Immunosuppressives, Others

      120 Participants Needed

      MISHA Knee System for Osteoarthritis

      New York, New York
      Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment. This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Poor Bone Quality, Ligamentous Instability, Inflammatory Joint Disease, Others

      100 Participants Needed

      Arterial Embolization for Osteoarthritis

      New York, New York
      This trial is testing a new treatment where tiny beads are used to block certain blood vessels in the knee. It is aimed at people with mild to moderate knee osteoarthritis who might not benefit from usual treatments. The goal is to see if blocking these blood vessels can safely reduce pain and swelling.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:30 - 80

      Key Eligibility Criteria

      Disqualifiers:Infection, Malignancy, Renal Dysfunction, Others

      38 Participants Needed

      Nutritional Supplements for Joint Replacement Recovery

      New York, New York
      The purpose of this study is to determine the effect on hematological markers of nutritional intervention on nutritionally deficient patients following total joint replacement surgery.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:55+

      Key Eligibility Criteria

      Disqualifiers:Septic Arthritis, Allergy, Protein Malabsorption, Eating Disorders, End Stage Renal, Others

      72 Participants Needed

      Total Knee Replacement for Osteoarthritis

      New York, New York
      The purpose of this study is to evaluate the safety and effectiveness of the JOURNEY™ II CR Total Knee System in subjects with degenerative joint disease (DJD) requiring primary total knee replacement.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Age:22 - 75

      Key Eligibility Criteria

      Disqualifiers:Immunosuppressive Disorder, Malignant Tumor, Osteoporosis, Others
      Must Not Be Taking:Fibromyalgia Medication

      170 Participants Needed

      Shoulder Replacement Techniques for Arthritis

      New York, New York
      Design: Prospective, randomized clinical trial, of 120 patients requiring a total shoulder replacement (TSR). Purpose: To collect and evaluate long-term clinical data on patients whose total shoulder replacement (TSR) is performed using the traditional surgical approach (called the subscapularis release approach) as compared to patients who have a TSR procedure done using a newer surgical approach (called the rotator cuff sparing approach).
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:21+

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      108 Participants Needed

      Why Other Patients Applied

      "I’m allergic to so many standard arthritis drugs, so I've been researching some of the newest ones still in the research phase. I'm hoping to find out if I'd be a good match—it would be great to find something that works (and, if not, at least contribute to the cause)."

      TJ
      Arthritis PatientAge: 79

      "I have been struggling with severe knee pain since my service in the military. I am only 52! I miss doing the things I used to do."

      NA
      Arthritis PatientAge: 55

      "I've been 17+ years in pain with bilateral osteoarthritis. PRP and HA injections have not helped. Physical therapy has helped only to a certain degree. I'm looking for new treatment options before considering replacement. "

      RH
      Arthritis PatientAge: 39

      "I am an active athlete who is not ready or willing to stop my activities because of knee pain at 42. I have tried cortisone shots and found they only temporary mask the issue, or even cause more problems later. That's why I started researching medical studies."

      GM
      Arthritis PatientAge: 44

      "I’ve tried several meds without too much relief. Injections only work on my right knee but not much on the left knee. My pain is nearly unbearable at this point. Hoping to learn about what promising drugs exist in trials."

      YV
      Arthritis PatientAge: 61
      Match to a Osteoarthritis Trial

      Calypso Knee System for Osteoarthritis

      New York, New York
      This trial evaluates the safety and effectiveness of the Calypso Knee System, a device for knee pain relief, in adults aged 25-65 with medial knee osteoarthritis. The device supports the damaged area of the knee to reduce pain and improve function.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Age:25 - 65

      Key Eligibility Criteria

      Disqualifiers:Not Listed

      81 Participants Needed

      Enekinragene Inzadenovec for Knee Arthritis

      Brooklyn, New York
      The goal of this clinical trial is to learn if a single knee injection of different doses (Dose A and Dose B) of an investigation product PCRX-201, following steroid pretreatment, is safe and tolerable in male of female patients 45 to 80 years old with osteoarthritis of the knee. It will also learn how the body reacts to the PCRX-201 injection and how effective the treatment is. Researchers will compare Dose A and Dose B of PCRX-201 versus placebo from Week 1 through Week 52 to assess adverse events. Researchers will also explore how PCRX-201 may impact knee pain and joint function over time. Participants will be asked to * Visit the clinic for pretreatment and drug administration * Visit the clinic for checkups and tests: 1. Screening through Week 52: intially weekly, bi-weekly, later monthly 2. Week 53 through Week 260 (Year 5): 8 visits throughout the period

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 2
      Age:45 - 80

      Key Eligibility Criteria

      Disqualifiers:Autoimmune Disorders, Infections, Unstable Knee, Others
      Must Be Taking:Steroids

      135 Participants Needed

      Adipose Tissue Allograft for Knee Arthritis

      New York, New York
      The purpose of this study is to evaluate the safety profile of BRC-OA for pain treatment in patients with mild to severe OA of the knee, focusing particularly on two distinct doses. Alongside safety assessments, the study also aims to investigate the initial efficacy of BRC-OA in treating pain among these patients. The study product is a cryopreserved devitalized adipose tissue allograft (BRC-OA). BRC-OA is composed of a devitalized human adipose particulate that retains the inherent properties of adipose such as tissue architecture, extracellular matrix, and signaling molecules.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 1, 2

      Key Eligibility Criteria

      Disqualifiers:BMI > 40, Knee Surgery, Others
      Must Not Be Taking:Anticoagulants, Immunosuppressives, Marijuana, Others

      42 Participants Needed

      Bone Marrow Aspirate for Knee Injuries

      New York, New York
      This study will examine whether using bone marrow aspirate (BMA) during knee arthroscopy surgery can improve patient outcomes. The investigators will enroll 50 patients who need knee arthroscopy surgery for meniscus injuries or cartilage damage. Like flipping a coin, patients will be randomly assigned to one of two groups of 25 patients each. One group will receive standard arthroscopic surgery plus an injection of bone marrow aspirate, while the other group will receive standard surgery plus a saline (salt water) injection. During surgery, for patients in the treatment group, approximately 4mL (less than one teaspoon) of bone marrow will be taken from their hip bone using a special needle system. A small amount (1mL) will be sent to the laboratory for testing. Patients will be followed for 12 months after surgery and will complete questionnaires about their pain levels and knee function at several time points: before surgery, 2 weeks, 6 weeks, 3 months, 6 months, and 12 months after surgery. These questionnaires will ask about pain, daily activities, and overall improvement.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:18 - 64

      Key Eligibility Criteria

      Disqualifiers:Prior Knee Surgery, Anemia, Others
      Must Not Be Taking:DMARDs, Steroids

      50 Participants Needed

      Bone Marrow Aspirate for ACL Injuries

      New York, New York
      The goal of this pilot randomized clinical trial is to look into the efficacy of concentrated bone marrow aspirate (cBMA) in improving post traumatic osteoarthritis (PTOA) symptoms in patients undergoing revision anterior cruciate ligament reconstruction surgery. The main questions it aims to answer are whether clinical outcomes, such as pain, are improved in patients who get cBMA with surgery, if there is a change in circulating markers of inflammation and what part of the cellular and molecular composition of cBMA may explain its effects.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Phase 4
      Age:18 - 55

      Key Eligibility Criteria

      Disqualifiers:Inflammatory Arthritis, Joint Sepsis, Avascular Necrosis, Others
      Must Not Be Taking:Corticosteroids, Hyaluronic Acid, PRP, Others

      40 Participants Needed

      Shockwave Therapy for Chronic Knee Pain

      West Orange, New Jersey
      This trial is testing a non-invasive treatment using sound waves to help people with knee arthritis who have not improved with standard treatments. The goal is to see if this new method can reduce pain and improve knee function better than current care options. Wearable long-duration low-intensity ultrasound is an emerging non-invasive and non-narcotic therapy for the daily treatment of musculoskeletal pain.
      No Placebo Group

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:30 - 80

      Key Eligibility Criteria

      Disqualifiers:Autoimmune Diseases, Bilateral BMLs, Others
      Must Not Be Taking:Glucocorticoids, Bisphosphonates

      15 Participants Needed

      Dorsal Root Ganglion Stimulation for Knee Arthritis

      New York, New York
      Dorsal root ganglion stimulation (DRG-S) may be able to treat mechanical pain caused by tissue injury or damage such as trauma or arthritis in addition to pain caused by nerve dysfunction or injury. The purpose of this study is to determine if dorsal root ganglion stimulation (DRG-S) can effectively treat arthritic pain of the knee.
      No Placebo Group

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Unphased
      Age:21+

      Key Eligibility Criteria

      Disqualifiers:Non-English, Pregnancy, BMI >45, Others
      Must Not Be Taking:Opioids

      30 Participants Needed

      Fat Cell Injection for Knee Osteoarthritis

      Cedar Knolls, New Jersey
      This trial tests if injecting special cells from a patient's own fat can reduce pain and improve function in people with knee osteoarthritis. These cells have been investigated in various studies for their potential to treat knee osteoarthritis by reducing pain and improving function.
      Pivotal Trial (Near Approval)

      Trial Details

      Trial Status:Active Not Recruiting
      Trial Phase:Phase 3
      Age:35 - 85

      Key Eligibility Criteria

      Disqualifiers:Rheumatoid Arthritis, Lupus, Psoriatic Arthritis, Others
      Must Not Be Taking:Anticoagulants, Immunosuppressants, Steroids, Others

      114 Participants Needed

      Hip Implant for Hip Replacement

      Livingston, New Jersey
      The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Freedom Constrained Vivacit-E Acetabular Liners in primary and revision total hip arthroplasty.
      No Placebo Group

      Trial Details

      Trial Status:Enrolling By Invitation
      Trial Phase:Unphased

      Key Eligibility Criteria

      Disqualifiers:Infection, Osteoporosis, Metabolic Disorders, Others

      202 Participants Needed

      Brain Stimulation + Yoga for Osteoarthritis

      Sherbrooke, Quebec
      People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to complex nervous system changes, making current treatments, like exercise, not very successful. To address this, researchers suggest a new approach combining two things: a brain stimulation technique called Transcranial Direct Current Stimulation (tDCS) and yoga. TDCS helps with pain by changing how the brain works, and yoga, a safe practice, focuses on overall well-being. Together, the investigators aim to improve how the nervous system works from top to bottom. The research project wants to change how the arthritis pain is being managed by focusing on how it works. The investigators plan to test this combo in a study comparing real tDCS plus yoga with fake tDCS plus yoga. The investigators will look not only at pain but also at other measures related to pain and how the nervous system works. This new mix could be a meaningful way to reduce pain for people with knee arthritis.

      Trial Details

      Trial Status:Recruiting
      Trial Phase:Unphased
      Age:45+

      Key Eligibility Criteria

      Disqualifiers:Systemic Inflammatory Arthritis, Neurological Conditions, Others

      68 Participants Needed

      12345

      Know someone looking for new options?
      Spread the word

      Why We Started Power

      We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.

      Bask
      Bask GillCEO at Power
      Learn More About Trials
      How Do Clinical Trials Work?Are Clinical Trials Safe?What Can I Expect During a Clinical Trial?
      Match to a Trial
      Match to a Trial

      Frequently Asked Questions

      How much do Osteoarthritis clinical trials in Boston, MA pay?

      Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.

      How do Osteoarthritis clinical trials in Boston, MA work?

      After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Osteoarthritis trials in Boston, MA 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length in Boston, MA for Osteoarthritis is 12 months.

      How do I participate in a study as a "healthy volunteer"?

      Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility in Boston, MA several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.

      What does the "phase" of a clinical trial mean?

      The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.

      Do I need to be insured to participate in a Osteoarthritis medical study in Boston, MA?

      Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

      What are the newest Osteoarthritis clinical trials in Boston, MA?

      Most recently, we added Bone Marrow Aspirate for Knee Injuries, Inulin for Osteoarthritis and Cannabinoids for Osteoarthritis to the Power online platform.