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110 Autism Trials near San Diego, CA
Power is an online platform that helps thousands of Autism patients discover FDA-reviewed trials every day. Every trial we feature meets safety and ethical standards, giving patients an easy way to discover promising new treatments in the research stage.
Learn More About PowerARD-501 for Autism
Las Vegas, Nevada
This trial tests a new medication called ARD-501 for safety and effectiveness in people with Autism Spectrum Disorder (ASD). Participants will receive the medication in two different doses to compare results. The goal is to see if ARD-501 can help improve symptoms of ASD.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 2
Age:17 - 30
Key Eligibility Criteria
Disqualifiers:Seizure Disorder, Major Depressive Disorder, Others
Must Not Be Taking:Benzodiazepines, Cannabinoids, Opioids, Others
12 Participants Needed
Marijuana-based Drug for Anxiety in Autism
Phoenix, Arizona
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC. The main questions it aims to answer are:
Will a marijuana-based drug help anxiety in autistic adults?
Anxiety can make socializing and working more difficult for people. Researchers will compare a marijuana based drug (that is mostly CBD with a small amount of THC) to a placebo (a look-alike substance that contains no drug) to see if the drug makes symptoms of anxiety better.
Participants will take the drug (or a placebo) every day for 8 weeks and keep a diary to record the time they took the drug, and their feelings each day. The drug is taken orally in drops once or twice a day. The study staff will speak to the participants weekly either over the phone or in the clinic. Clinic visits once every 2 weeks for checkups and tests. The researchers will make sure participants are healthy and see if there are any changes in anxiety.
Trial Details
Trial Status:Not Yet Recruiting
Trial Phase:Phase 2
Age:18 - 45
Key Eligibility Criteria
Disqualifiers:Psychotic Disorder, Substance Use, Others
Must Not Be Taking:Opiates, Methamphetamine, Cocaine, Others
108 Participants Needed
Photobiomodulation for Autism
Phoenix, Arizona
For this study, the proposed intervention will be noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM) - to the brains of autistic children. This will occur, twice a week, for 10 weeks. The NIR light is delivered to specific brain areas by Cognilum, a wearable device developed by Jelikalite. The expected outcome is improved focus, improved eye contact, improved speech, improved behavior, and gains in functional skills. Cognilum may impact the clinical practice of treating autism. At the beginning, at five weeks, and at the end of study, the clinician will complete the CARS-2, SRS, CGI, and a caregiver interview; additionally, questionnaires will be administered to caregivers during one of the 1-hour weekly treatment sessions.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:4 - 12
Key Eligibility Criteria
Disqualifiers:Self-abusive Behavior, GERD, Genetic Syndromes, Others
Must Not Be Taking:Stimulants, Antipsychotics, Antihistamines
30 Participants Needed
Leucovorin for Autism
Phoenix, Arizona
This trial tests a liquid form of leucovorin calcium in young children with autism spectrum disorder (ASD) to see if it improves their social communication and behavior. The study focuses on children who have significant social and communication challenges. The treatment aims to enhance brain function, potentially leading to better communication and interaction skills.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:30 - 60
Key Eligibility Criteria
Disqualifiers:Epilepsy, Genetic Syndromes, Liver Disease, Others
Must Not Be Taking:Chemotherapy, Antimalarial, Immunosuppressive, Antibiotics
80 Participants Needed
Levoleucovorin Calcium for Autism
Phoenix, Arizona
This trial is testing a liquid form of leucovorin calcium to see if it can help young children with autism improve their language skills and behavior. The study involves young children who have autism and language delays. The treatment aims to enhance brain function and development. Leucovorin calcium has shown potential benefits in improving verbal communication and behavior in children with autism spectrum disorder (ASD) who test positive for cerebral folate receptor autoantibodies.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:30 - 60
Key Eligibility Criteria
Disqualifiers:Epilepsy, Genetic Syndromes, Liver Disease, Others
Must Not Be Taking:Chemotherapy, Antimalarial, Immunosuppressive, Antibiotics
80 Participants Needed
Folinic Acid for Language Impairment in Autism Spectrum Disorder
Phoenix, Arizona
This trial is testing folinic acid, a vitamin, to see if it can help children with autism who have language problems. The study focuses on whether this vitamin can improve brain function and language skills. Children with moderate language issues will participate. Folinic acid has been studied for its potential to improve verbal communication in children with autism and language impairment.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 2
Age:5 - 17
Key Eligibility Criteria
Disqualifiers:Major Depression, Bipolar, Psychotic Disorder, Others
Must Not Be Taking:Anticonvulsants, Bactrim, Valproic Acid
56 Participants Needed
Mindfulness Intervention for Autism Spectrum Disorder
Phoenix, Arizona
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve co-occurring mental health symptoms.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:13 - 18
Key Eligibility Criteria
Disqualifiers:Non-verbal, IQ <70, Physical Disability, Others
28 Participants Needed
This trial tests a treatment called Microbiota Transfer Therapy (MTT) for children with Autism Spectrum Disorder and gut problems. It uses antibiotics to clear bad bacteria, cleans the bowel, and then adds good bacteria from donor stool over a few months. The goal is to see if this helps improve their symptoms. Microbiota Transfer Therapy (MTT) has shown significant improvements in gastrointestinal and autism symptoms in previous studies, with benefits persisting for some time after treatment.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 2
Age:5 - 17
Key Eligibility Criteria
Disqualifiers:Single-gene Disorders, Major Brain Malformation, Others
Must Not Be Taking:Antibiotics, Probiotics, Psychotropics, Others
50 Participants Needed
Mindfulness Training for Autism
Tempe, Arizona
The purpose of this study to measure brain functioning before and after stress-reduction classes to better understand how symptom improvements relate to brain functioning in adults with ASD (Autism Spectrum Disorder). Participants will be randomly assigned to one of two stress reduction classes that will meet once a week for 8 weeks. One group will complete a structured training program called Mindfulness Based Stress Reduction (MBSR) that involves teaching about increased mindfulness strategies and gentle stretching. The other group will review relaxation techniques and other stress reduction strategies and will include social support. Structural and functional MRI, EEG, and behavioral self-report data will be collected to understand more about how the brain changes in subtle ways when people feel better and are more aware of their emotional state.
No Placebo Group
Trial Details
Trial Status:Active Not Recruiting
Key Eligibility Criteria
Disqualifiers:Not Listed
108 Participants Needed
The investigators propose to investigate Microbiota Transfer Therapy (MTT) for treating patients with Autism-spectrum disorder with Gastrointestinal disorders (constipation, diarrhea, and/or abdominal pain). MTT involves a combination of 14 days of oral vancomycin (an antibiotic to kill pathogenic bacteria), followed by 1 day of bowel cleanse using Miralax, followed by 5 days of high dose MTP-101P with an antacid, followed by 12 weeks of a lower maintenance dose of MTP-101P with an antacid.
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Phase 2
Age:4 - 18
Key Eligibility Criteria
Disqualifiers:Single-gene Disorder, Major Brain Malformation, Severe GI Problems, Others
Must Not Be Taking:Antibiotics, Probiotics, Psychotropics, Others
60 Participants Needed
Diné Parents Taking Action for Autism
Flagstaff, Arizona
The goal of this clinical trial is to learn if a family support program helps Navajo parents and guardians of children with autism spectrum disorder (ASD) or other developmental concerns. The main questions it aims to answer are:
* Is the program something families find useful and easy to take part in?
* Does the program raise parents' knowledge and confidence in using strategies that support their child's development?
* Does the program help children improve in areas such as social communication?
Researchers will compare two groups:
* One group of parents will join the program right away.
* The other group will join the program after waiting.
Participants will:
* Be randomly placed into the "immediate" or "waitlist control" group using simple randomization.
* Take part in sessions led by trained Navajo Family Advisors, who are parents of children with ASD.
* Learn and practice strategies they can use at home to support their child
* Answer surveys about their experience, knowledge, and their child's progress
No Placebo Group
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Unphased
Key Eligibility Criteria
Disqualifiers:Non-Navajo, Child Age 13+, Others
29 Participants Needed
Parent Coaching for Autism
Sunnyvale, California
The goal of this clinical trial is to learn about the journey of families after their child's diagnosis of autism and to help parents understand autism and get the right treatments for their child. This study is for parents of children just diagnosed with autism who are:
* Age greater than 1 and up to 5 years old;
* Hispanic/Latino OR Black/African-American OR have Medi-Cal as primary health insurance; AND
* Live in one of the following counties in California (Alameda, Contra Costa, Marin, Monterey, Napa, San Benito, San Francisco, San Mateo, Santa Clara, Santa Cruz, Solano, or Sonoma).
The main questions it aims to answer are:
* Whether parent coaching through Project AFECT leads to decreased parental stress and increased parental confidence;
* Whether family navigation through Project AFECT leads to increased number of referrals to early intervention and educational services and reduced wait times to autism treatments;
* Whether children whose parents receive Project AFECT intervention show increased language skills compared to children whose parents did not receive intervention.
Participants will be asked to:
* Complete surveys at enrollment and 3 and 6 months later.
* Work with Project AFECT Coach.
Researchers will compare control and intervention groups to see if Project AFECT leads to improved parent and child outcomes.
No Placebo Group
Trial Details
Trial Status:Active Not Recruiting
Trial Phase:Unphased
Age:12 - 60
Key Eligibility Criteria
Disqualifiers:Non-legal Guardians, No Autism Diagnosis
200 Participants Needed
Pregnenolone for Autism
Stanford, California
This trial is testing pregnenolone, a natural hormone in the brain, to see if it can help people with autism. Pregnenolone is part of a neurosteroid pathway that has been studied for its potential therapeutic value in stress and drug abuse-related disorders. The goal is to find out if it can reduce irritability and sensitivity to sensory differences, and improve social communication. Researchers hope this will lead to better treatments for autism.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:14 - 25
Key Eligibility Criteria
Disqualifiers:Schizophrenia, Schizoaffective, Alcohol Use, Others
Must Not Be Taking:Steroid Medications
40 Participants Needed
Suvorexant for Sleep Issues in Children with Autism
Stanford, California
This trial is testing suvorexant, a sleep aid, in children and adolescents with Autism Spectrum Disorder who have sleep problems. Suvorexant helps people fall asleep and stay asleep by blocking wakefulness signals in the brain.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:13 - 17
Key Eligibility Criteria
Disqualifiers:Schizophrenia, Seizure Disorder, Severe Hepatic Insufficiency, Others
Must Not Be Taking:Beta-blockers, Benzodiazepines, Antiepileptics, Others
26 Participants Needed
Zolpidem for Sleep Disturbances in Children with Autism
Stanford, California
This trial is testing zolpidem, a medication that helps people fall asleep, in children and adolescents with Autism Spectrum Disorder (ASD). These children often have trouble sleeping, and typical treatments may not work for them. Zolpidem works by calming the brain, making it easier to fall asleep. Zolpidem is a medication commonly used to treat sleep problems by helping people fall asleep, and it has been studied in various populations including healthy adults and those with insomnia.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:8 - 17
Key Eligibility Criteria
Disqualifiers:Schizophrenia, Seizure Disorder, Liver Pathology, Others
Must Not Be Taking:Beta-blockers, Benzodiazepines, Antidepressants, Others
26 Participants Needed
Diphenhydramine for Sleep in Children with Autism
Stanford, California
This trial is testing if diphenhydramine can help children and teens with Autism Spectrum Disorder sleep better. Diphenhydramine is usually used for allergies but also makes people sleepy by blocking certain chemicals in the body. Diphenhydramine has been shown to be effective in reducing the time it takes to fall asleep and the number of times children wake up during the night.
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:8 - 17
Key Eligibility Criteria
Disqualifiers:Schizophrenia, Seizure Disorder, Migraine, Others
Must Not Be Taking:Beta-blockers, Benzodiazepines, Antiepileptics, Others
26 Participants Needed
Sleep Restriction Therapy for Autism and Sleep Disorders
Stanford, California
The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD). Treatment will be delivered via secure telemedicine platform and consist of parent-training in delivering the intervention.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:6 - 12
Key Eligibility Criteria
Disqualifiers:Severe Psychiatric Disorder, Epilepsy, Others
25 Participants Needed
AI Modules for Improving Social Communication in Autism
Stanford, California
The purpose of this study is to identify whether researched and commonly used face-to-face interventions can be effectively implemented through artificial intelligence (AI) using an application on the phone or computer. The investigators plan to recruit verbal individuals diagnosed with autism spectrum disorder who demonstrate challenges with socialization. Modules focusing on various difficulties experienced by autistic individuals will provide practice and feedback using voice recognition and feedback. If effective, this intervention can be scaled up to provide cost-effective accessible assistance to individuals, particularly those who do not have access to care or prefer to secure services in the comfort of their own homes.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:11 - 35
Key Eligibility Criteria
Disqualifiers:Intellectual Impairment, Non English Speaking, Others
540 Participants Needed
Early Intervention Program for Autism Spectrum Disorder
Stanford, California
This trial is testing a program where children spend time each week in a special preschool or at home doing activities. The goal is to help children with developmental disorders, like Autism, improve their social communication skills. By engaging in these structured activities, the children can learn to communicate and interact better.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:2 - 5
Key Eligibility Criteria
Disqualifiers:Severe Psychiatric Disorder, Others
75 Participants Needed
Digital Game Therapy for Autism
Stanford, California
The following study aims to assess the efficacy of the game-based digital therapeutic, GuessWhat, in improving adaptive socialization skills in children with Autism Spectrum Disorder (ASD). GuessWhat is a mobile application (available for free for iOS and Android) which contains a suite of games: pro-social charades, emotion guessing, and quiz. Participant families will use their personal smartphones to download the app and play it with their child according to a predetermined regimen.
No Placebo Group
Trial Details
Trial Status:Not Yet Recruiting
Trial Phase:Unphased
Age:3 - 12
Key Eligibility Criteria
Disqualifiers:Genetic Syndromes, Epilepsy, Others
1000 Participants Needed
Why Other Patients Applied
"I've been struggling with ADHD and anxiety since I was 9 years old. I'm currently 30. I really don't like how numb the medications make me feel. And especially now, that I've lost my grandma and my aunt 8 days apart, my anxiety has been even worse. So I'm trying to find something new."
FF
ADHD PatientAge: 31
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
WR
Obesity PatientAge: 58
"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."
ZS
Depression PatientAge: 51
"As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."
IZ
Healthy Volunteer PatientAge: 38
"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."
ID
Pancreatic Cancer PatientAge: 40
N-acetylcysteine for Autism
Palo Alto, California
This trial tests NAC, a safe nutritional supplement, to see if it can reduce repetitive behaviors in children with autism by balancing brain chemicals.
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2, 3
Age:3 - 12
Key Eligibility Criteria
Disqualifiers:Genetic Abnormalities, Severe Psychiatric Disorder, Others
Must Not Be Taking:Glutathione Agents
144 Participants Needed
N-acetylcysteine for Autism
Stanford, California
This trial is testing a nutritional supplement called N-acetylcysteine (NAC) to help children with autism spectrum disorder. NAC has shown promise in smaller studies for reducing repetitive behaviors. The study aims to understand how NAC works and its effects on these behaviors. NAC has been studied for its potential to reduce irritability and self-injurious behaviors in children with autism spectrum disorder (ASD).
No Placebo Group
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Enrolling By Invitation
Trial Phase:Phase 2, 3
Age:3 - 13
Key Eligibility Criteria
Disqualifiers:Significant Medical Problems, Others
48 Participants Needed
Telehealth vs In-Person Behavior Therapy for Autism
Stanford, California
The purpose of the research is to determine whether parent-mediated behavior therapy for challenging behavior commonly displayed by children with autism spectrum disorder (ASD) can be as effective when delivered via telehealth as when delivered in-person.
Pivotal Trial (Near Approval)
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2, 3
Age:2 - 7
Key Eligibility Criteria
Disqualifiers:Severe Behavior, Sensory Impairment, Genetic Condition, Others
90 Participants Needed
N-Acetylcysteine for Autism
Stanford, California
This trial aims to see if NAC, a safe nutritional supplement, can help reduce repetitive behaviors in children with autism by balancing brain chemicals. N-Acetylcysteine (NAC) has been studied for its potential benefits in treating obsessive-compulsive spectrum disorders and irritability in autism spectrum disorders.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:3 - 12
Key Eligibility Criteria
Disqualifiers:Genetic Abnormalities, Severe Psychiatric Disorder, Others
Must Not Be Taking:Antioxidants, Glutathione Prodrugs
24 Participants Needed
Esomeprazole for Autism
Stanford, California
Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication and the presence of repetitive/stereotyped behaviors. The objective of the study is to evaluate the efficacy of Esomeprazole as a treatment for social communication deficits in children with Autism Spectrum Disorder (ASD). This prospective 12 week open-label study will invite 25 children with ASD between the ages of 2 and 6 years of age to participate.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Phase 2
Age:2 - 6
Key Eligibility Criteria
Disqualifiers:Schizophrenia, Schizoaffective, Psychotic, Others
25 Participants Needed
Behavioral Therapy for Autism
Stanford, California
The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty tolerating changes in routine) in youth with autism spectrum disorder (ASD). Treatment will be delivered via secure telemedicine platform and consist of a combination of parent-training and parent-mediated intervention with the child.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:4 - 17
Key Eligibility Criteria
Disqualifiers:Non-english Speaking, Reside Outside US, Others
44 Participants Needed
Pivotal Response Treatment for Autism
Stanford, California
The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young children with autism spectrum disorder (ASD) with significant language delay. The two groups will also be compared to a control group that consists of children who are receiving treatment as usual (TAU).
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:2 - 5
Key Eligibility Criteria
Disqualifiers:Severe Psychiatric Disorder, ABA 15+ Hours, Others
120 Participants Needed
Transcranial Magnetic Stimulation for Autism
Stanford, California
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:12 - 45
Key Eligibility Criteria
Disqualifiers:Seizures, Pregnancy, Substance Use, Bipolar, Others
Must Not Be Taking:Clozapine, Others
67 Participants Needed
Specialized Employment Program for Autism
Palo Alto, California
Individuals with autism spectrum disorder (ASD) have significantly higher levels of unemployment and underemployment compared to their typically developing peers and all other groups with neurodevelopmental disorders, even though major companies that have employed and trained young people with ASD acclaim their significant innovations in their companies. The investigators hope to examine the effects of specialized employment support programs, over current traditional vocational rehabilitation approaches, for adults with ASD on their ability to maintain steady employment and overall benefit to the organizations at which they will be employed.
The investigators predict that Stanford University's Neurodiversity at Work (NaW) Program will improve employment outcomes and positively impact the overall quality of life of individuals with ASD in this program. The investigators hope that the findings of the study will lead to the advancement of programs aimed to support individuals with ASD.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:18 - 55
Key Eligibility Criteria
Disqualifiers:Bipolar, Schizophrenia, Others
80 Participants Needed
Telehealth Parent Training for PRT
Stanford, California
There is an urgent need for improved access to effective autism treatments. With advances in technology, distance learning models have particular promise for families who cannot access evidence-based parent training locally or may be on long wait-lists for behavioral treatments. Pivotal Response Treatment (PRT) is an established treatment for autism spectrum disorder (ASD); however, a telehealth PRT model has not yet been evaluated in a controlled trial. This study will examine the effects of training parents in PRT via secure video conferencing and investigate 1) whether parents can learn via telehealth to deliver PRT in the home setting (PRT-T) and 2) whether their children will show greater improvement in functional communication skills compared to children in a waitlist control group. Participants will include 40 children age 2 to 5 years with ASD and significant language delay. Eligible children will be randomly assigned to either PRT-T (N=20) or waiting list (N=20). Weekly 60-minute parent training sessions will be delivered for 12 weeks via secure video conferencing software by a PRT-trained study therapist. The effects of PRT-T on parent fidelity of PRT implementation, child communication deficits including frequency of functional verbal utterances, and parent-report of communication skills on standardized questionnaires will be evaluated. This research will provide a foundation for wider dissemination of technology-based solutions to improve access to ASD treatment.
No Placebo Group
Trial Details
Trial Status:Recruiting
Trial Phase:Unphased
Age:2 - 5
Key Eligibility Criteria
Disqualifiers:Non-English, Severe Psychiatric, Severe Seizures, Others
40 Participants Needed
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