Cognitive Behavioral Therapy for Mental Health

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, Los Angeles
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how cognitive behavioral therapy (CBT) can reduce repetitive negative thinking (RNT), a common mental health issue. Researchers aim to identify the most effective components of RNT-focused CBT. Participants will receive various types of training, such as becoming more specific in their thoughts or practicing self-compassion. The Calming Minds Study seeks individuals who frequently experience negative thoughts and have access to a smartphone and the internet. As an unphased trial, it offers a unique opportunity to contribute to the understanding and improvement of mental health therapies.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but if your antidepressant or anxiety medication has changed in dose or type in the last 6 weeks, you may not be eligible to participate.

What prior data suggests that cognitive-behavioral therapy is safe for mental health treatment?

Research shows that cognitive-behavioral therapy (CBT), including techniques from the "Calming Minds Study," is generally safe and well-tolerated. Here's a breakdown of the study's components:

1. **Be Specific (Concreteness Training):** Studies have found that concreteness training can help reduce anxiety and depression. It complements traditional treatments and typically does not cause significant side effects.

2. **Be Kind (Self-Compassion Training):** Research indicates that self-compassion training can lower stress and improve mental health. It is safe and linked to positive mental well-being.

3. **Be Present (Absorption in Experience):** Mindfulness techniques, which focus on being present, are often part of CBT. Research supports these methods as safe ways to manage anxiety and stress.

4. **Break Habit (Habit Reversal):** Habit reversal training helps change habits, including repetitive negative thinking. Studies show it is effective and safe.

Overall, extensive research on these CBT components consistently shows they are safe for participants. Severe side effects are rare, making them a reliable choice for mental health treatment.12345

Why are researchers excited about this trial?

Researchers are excited about the Cognitive Behavioral Therapy (CBT) techniques being explored because they offer a fresh approach to mental health treatment. Unlike standard psychoeducation or traditional CBT, these methods focus on enhancing specificity, self-compassion, and mindfulness, along with breaking patterns of repetitive negative thinking. These techniques aim to make therapy more personalized and effective by directly targeting thought patterns and emotional responses. By integrating these elements, the hope is to offer more comprehensive support for mental health, potentially leading to faster and more sustainable improvements for individuals.

What evidence suggests that this trial's treatments could be effective for reducing repetitive negative thinking?

This trial will explore various approaches within Cognitive Behavioral Therapy (CBT) to address repetitive negative thinking (RNT) in mental health. Participants in different arms of the trial will receive training in specific CBT techniques. Studies have shown that CBT effectively reduces RNT by helping people change their thought patterns. Some participants will focus on breaking the habit of negative thinking, while others will receive training in self-compassion, which research has proven to boost mental health and well-being. Additionally, focusing on the present moment is another technique under study, known to help stop negative thought cycles. Overall, CBT has a strong track record of improving symptoms of conditions like anxiety and depression, making it a promising approach for addressing RNT.34567

Are You a Good Fit for This Trial?

This trial is for adults experiencing anxiety, depression, or repetitive negative thinking. Participants should be willing to try therapy techniques and complete questionnaires over a 16-week period.

Inclusion Criteria

Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher)
Able to provide a valid Imperial Valley College email address
Access to internet
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Exclusion Criteria

Self-reported current or past diagnosis or treatment for Bipolar disorder
Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence
Self-reported current diagnosis or currently receiving, or waiting to receive, treatment for alcohol abuse/dependence
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a digital therapy program with RF-CBT components and coaching sessions

16 weeks
3-6 meetings with a coach

Follow-up

Participants complete online questionnaires to measure changes in symptom experiences

52 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Calming Minds Study

Trial Overview

The study tests different parts of cognitive-behavioral therapy (CBT) aimed at reducing repetitive negative thoughts. Techniques include being present, breaking habits, being specific and kind, plus psychoeducation. Changes are measured over 16 weeks.

How Is the Trial Designed?

16

Treatment groups

Experimental Treatment

Active Control

Group I: Break Habit + Be Specific+ Be PresentExperimental Treatment4 Interventions
Group II: Break Habit + Be Specific + Be KindExperimental Treatment4 Interventions
Group III: Break Habit + Be SpecificExperimental Treatment3 Interventions
Group IV: Break Habit + Be PresentExperimental Treatment3 Interventions
Group V: Break Habit + Be Kind + Be PresentExperimental Treatment4 Interventions
Group VI: Break Habit + Be KindExperimental Treatment3 Interventions
Group VII: Break HabitExperimental Treatment2 Interventions
Group VIII: Be Specific + Be PresentExperimental Treatment3 Interventions
Group IX: Be Specific + Be Kind + Be PresentExperimental Treatment4 Interventions
Group X: Be Specific + Be KindExperimental Treatment3 Interventions
Group XI: Be SpecificExperimental Treatment2 Interventions
Group XII: Be PresentExperimental Treatment2 Interventions
Group XIII: Be Kind + Be PresentExperimental Treatment3 Interventions
Group XIV: Be KindExperimental Treatment2 Interventions
Group XV: ALLExperimental Treatment5 Interventions
Group XVI: Psychoeducation OnlyActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, Los Angeles

Lead Sponsor

Trials
1,594
Recruited
10,430,000+

University of Exeter

Collaborator

Trials
207
Recruited
1,368,000+

Citations

Study Details | NCT07577401 | Calming Minds Study

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In brief: Cognitive behavioral therapy (CBT) - NCBI - NIH

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Cognitive behavioral therapy

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What is Rumination-Focused CBT?

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Rumination-Focused Cognitive Behavioral Therapy Reduces ...

RF-CBT uses functional analysis, experiential exercises, and repeated practice to identify and change the ruminative habit. This preregistered randomized ...