Meditation for Visual Impairment

MM
Overseen ByMonali Malvankar, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how meditation and a health enhancement program can improve the quality of life and mental health for people with irreversible age-related vision loss and their caregivers. Participants will either practice meditation, engage in a health enhancement program, or continue their usual care. The trial aims to determine which method best aids in coping with vision loss. Those with irreversible age-related vision loss who face significant daily challenges, or their caregivers, might be suitable candidates for this trial. Participants should be willing to join online training sessions and practice daily activities at home. As an unphased trial, this study offers a unique opportunity to explore innovative approaches to enhance well-being and support for those affected by vision loss.

Do I have to stop taking my current medications to join the trial?

The trial does not specify if you need to stop taking your current medications, but you cannot have any planned changes to mood-altering medications for the next 12 weeks.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that meditation is safe and can benefit people with vision loss. It can enhance quality of life and reduce eye pressure, which supports eye health. Studies have not reported any harmful effects from meditation.

The Health Enhancement Program's low-vision rehabilitation is well-received. It aids in tasks like reading and moving around, thereby improving quality of life. No serious side effects are associated with this type of rehabilitation.

Both meditation and the Health Enhancement Program appear safe for those with vision loss. Studies suggest these treatments are not only safe but also beneficial for improving mental and physical well-being.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores alternative ways to support patients with irreversible age-related vision loss and their caregivers. Unlike the standard care, which often involves no active treatment beyond what surgery can offer, the trial investigates meditation and a Health Enhancement Program (HEP) as supportive interventions. These approaches aim to improve quality of life through mental and emotional well-being rather than focusing solely on physical vision restoration. By comparing meditation and HEP, researchers hope to find out if these methods can enhance the daily lives of those affected by vision loss.

What evidence suggests that this trial's treatments could be effective for enhancing the quality of life and mental health of IARVL patients?

Research shows that low-vision rehabilitation programs, which participants in this trial may receive, can greatly benefit people with vision loss. Studies indicate that 44% to 50% of participants experience significant improvements in their ability to see and perform daily tasks after joining these programs. These improvements include clearer vision, better contrast sensitivity, and faster reading. Additionally, about 90% of people with vision impairment retain some sight that these programs can enhance. Overall, low-vision rehabilitation helps individuals with vision loss live more independently by improving their ability to perform everyday activities.678910

Who Is on the Research Team?

MM

Monali Malvankar

Principal Investigator

Western University, Canada

Are You a Good Fit for This Trial?

This trial is for individuals aged 50 or older with irreversible age-related vision loss (IARVL) and their caregivers. Participants must have good hearing, be able to sit comfortably for 30 minutes, commit to attending most training sessions, and practice at home twice daily for 20 minutes. They should not have any major mental health disorders other than depression or anxiety symptoms.

Inclusion Criteria

I can hear well enough to follow spoken directions and can sit comfortably for 30 minutes.
I am 50 years old or older.
I have low vision.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants undergo either the MEDITATION intervention or the Health Enhancement Program (HEP) with weekly sessions

12 weeks
Weekly sessions

Follow-up

Participants are monitored for retention, adherence, and changes in quality of life and mental health

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Low-vision rehabilitation program
  • No Intervention

Trial Overview

The study is testing the effectiveness of Meditation versus a Health Enhancement Program in improving life quality and mental health for patients with IARVL and their caregivers. It involves initial training sessions followed by regular follow-ups where participants will engage in either meditation or health education activities.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Group I: Health Enhancement Program (HEP)Experimental Treatment1 Intervention
Group II: MeditationActive Control1 Intervention
Group III: Treatment as UsualActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
678
Recruited
421,000+

London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
686
Recruited
427,000+

London Health Sciences Centre OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
668
Recruited
424,000+

Lawson Health Research Institute

Lead Sponsor

Trials
684
Recruited
432,000+

Citations

Clinically Meaningful Rehabilitation Outcomes of Low Vision ...

Forty-four to fifty percent of patients presenting for outpatient LVR show clinically meaningful differences in overall visual ability after LVR, and the ...

Mapping the Outcomes of Low-Vision Rehabilitation - PMC

Conclusions: Low vision rehabilitation interventions demonstrate clear benefits for visual acuity, contrast sensitivity, reading speed, and ...

The Effectiveness of Low-Vision Rehabilitation on ... - IOVS

It has been estimated that 90% of individuals with vision impairment have useful residual vision, which could benefit from low-vision rehabilitation programs.

How Effective is Low Vision Service Provision? A ...

37, A Low vision rehabilitation aims to improve the lives of people with sight loss by improving functional ability, and possibly more general aspects, such as ...

The Effectiveness of Low-Vision Rehabilitation in 2 Cohorts ...

Both groups demonstrated improvement in visual ability from baseline to 1 year (P < .001) (except for mobility in the control group). Overall visual ability ( ...

Low vision rehabilitation in improving the quality of life ... - PMC

This meta-analysis was designed to evaluate the efficacy of low vision rehabilitation in improving the quality of life (QoL) in visually impaired adults.

Mapping the Outcomes of Low-Vision Rehabilitation

Standardized outcome measures and long-term, inclusive research designs are needed to better understand the sustained and equitable impact of low-vision ...

Outcomes of Multidisciplinary Low Vision Rehabilitation in ...

Following LVR, our participants reported significant improvements in reading, mobility, visual information processing, and visual motor skills assessed using ...

Meeting the Challenge of Vision Loss in the United States

Among 468 adult patients seeking vision rehabilitation services, 47 percent achieved a minimum clinically important difference in overall visual ability between ...

Low-Vision-Entry-Level-Competencies- ...

Objective 4A Identify patient psychological signs and symptoms that may affect adjustment to vision impairment and outcomes of rehabilitation.