Brain Stimulation and Augmented Reality for Concussion
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether combining brain stimulation and balance exercises can reduce dizziness in people who have had a concussion. Specifically, it tests repetitive transcranial magnetic stimulation (rTMS), which uses magnetic pulses to target brain areas controlling movement. Participants will wear augmented reality glasses to interact with digital objects during balance tasks over 14 days. Ideal candidates are those who have experienced a mild traumatic brain injury (mTBI) and have been dizzy for more than three months after the injury. As an unphased trial, this study offers a unique opportunity to explore innovative treatments for post-concussion dizziness.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it mentions that you must be able to continue your current medical therapies during the study.
What prior data suggests that this brain stimulation and balance training protocol is safe for individuals with concussion-related dizziness?
Research has shown that repetitive transcranial magnetic stimulation (rTMS) is generally safe for both healthy individuals and those with brain conditions. Studies have found that when used following safety guidelines, rTMS is well-tolerated, and serious side effects are rare.
Other research has used rTMS to help manage symptoms after a concussion, such as reducing chronic headaches. As a noninvasive procedure, it doesn't involve surgery or entering the body, making it less risky than other brain stimulation methods.
Overall, rTMS is considered a safe option for treating brain-related issues. Many studies have tested it with positive results regarding safety.12345Why are researchers excited about this trial?
Researchers are excited about the potential of using Repetitive Transcranial Magnetic Stimulation (rTMS) for concussion treatment because it offers a non-invasive approach that directly targets brain areas involved in recovery. Unlike traditional treatments for concussions, which often involve rest and symptom management, rTMS uses magnetic fields to stimulate nerve cells in the brain and promote healing. This technique has the potential to accelerate recovery time and improve cognitive function without the need for medication. Additionally, the use of augmented reality in conjunction with rTMS could enhance visual and spatial processing, offering a comprehensive approach to concussion rehabilitation.
What evidence suggests that this trial's treatments could be effective for dizziness due to concussion?
Research has shown that repetitive transcranial magnetic stimulation (rTMS), which participants in this trial may receive, can help with concussion symptoms. One study found that people who received rTMS had better cognitive function than those who did not. Another study found that rTMS sessions reduced headaches and improved focus and daily activities. A small study also suggested that rTMS is a promising and manageable option for those with recent concussions. While some studies have mixed results, overall, rTMS appears to be a potential treatment for dizziness and other symptoms following a concussion.26789
Are You a Good Fit for This Trial?
This trial is for individuals with persistent dizziness due to a concussion, vertigo, or other vestibular disorders. Participants should be able to undergo brain stimulation and balance training. Details on specific inclusion and exclusion criteria are not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive repetitive transcranial magnetic stimulation (rTMS) paired with balance training using augmented reality for 14 days over 3 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Augmented reality vestibular rehabilitation therapy
- Repetitive Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation is already approved in United States, European Union, Canada for the following indications:
- Major depressive disorder
- Obsessive-compulsive disorder
- Migraines
- Major depressive disorder
- Obsessive-compulsive disorder
- Anxiety disorders
- Major depressive disorder
- Obsessive-compulsive disorder
Find a Clinic Near You
Who Is Running the Clinical Trial?
McMaster University
Lead Sponsor
Greenbank Concussion Clinic
Collaborator