Hypochlorous Acid for Prosthetic Graft Infection
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a study of the use of an antibacterial solution, Hypochlorous acid, to prevent infection in vascular surgery bypass grafts. The solution will be used at the end of operations to insert a prosthetic vascular surgery bypass graft, to wash the wound and the vascular bypass graft before the wound is closed. The patients in this study will be undergoing surgery for problems with narrowed and or blocked arteries. The presence or absence of a graft infection will be followed for 12 months following the surgery. Prosthetic vascular graft infections have significant implications for patients with high rates of death and amputation, hence preventing them will have significant benefits for patients and the health care system.
Are You a Good Fit for This Trial?
This trial is for people who are having surgery to get a prosthetic vascular bypass graft due to narrowed or blocked arteries. Participants must be eligible for this type of surgery and able to follow up for 12 months after the operation.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Hypochlorous acid
Trial Overview
The study tests whether washing the surgical wound and new vascular graft with hypochlorous acid at the end of surgery can help prevent infections, compared to standard care. Patients will be monitored for infection over one year.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Surgical wound lavage with hypochlorous acid after insertion of prosthetic vascular graft and prior to wound closure
Standard of care with no surgical wound lavage
Find a Clinic Near You
Who Is Running the Clinical Trial?
Hamilton Health Sciences Corporation
Lead Sponsor
McMaster University
Collaborator
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