Smoking and Cannabis Use Reduction for Pregnancy
(PICTURe Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to help pregnant individuals quit using tobacco and cannabis and remain smoke-free after giving birth. It focuses on a perinatal smoking cessation treatment that addresses prenatal depressive symptoms, which can complicate quitting. The trial seeks participants who are pregnant, less than 26 weeks along, and currently use tobacco and cannabis or did so before pregnancy. As an unphased trial, it offers a unique opportunity to contribute to research that could enhance maternal and infant health.
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. However, it focuses on reducing tobacco and cannabis use during pregnancy.
What prior data suggests that this perinatal smoking cessation treatment is safe for pregnant individuals?
Research shows that treatments to help quit smoking during pregnancy are generally safe and can lower risks for both the mother and baby. Studies have found that quitting smoking while pregnant leads to better outcomes, such as a lower chance of early delivery and stillbirth.
One study found that counseling and support, known as psychosocial interventions, effectively helped pregnant women stop smoking. This type of treatment increased the number of women who quit and reduced tobacco use. Other studies also report that quitting smoking during pregnancy improves health outcomes for newborns.
While specific safety details for the smoking cessation treatment in this trial are not provided, research strongly supports the general safety of quitting smoking during pregnancy. Always consult healthcare providers for personal advice and to understand potential risks and benefits.12345Why are researchers excited about this trial?
Researchers are excited about the perinatal smoking cessation treatment because it specifically targets smoking reduction during pregnancy, a critical period for both the mother and baby's health. Unlike standard nicotine replacement therapies or counseling, this approach is being tailored to the unique needs and challenges faced by pregnant individuals. The potential to improve outcomes for both mothers and their babies by focusing on a comprehensive, supportive strategy during pregnancy is what makes this treatment stand out from existing options.
What evidence suggests that this perinatal smoking cessation treatment might be effective for reducing smoking and cannabis use during pregnancy?
Research shows that treatments to help quit smoking during pregnancy can greatly increase the chances of expectant mothers stopping smoking. Studies have found that women who quit smoking while pregnant often face fewer risks of problems, such as early delivery and other negative effects on the baby. Specifically, programs offering counseling and support have proven very effective. For example, five studies found a significant increase in the number of women who stopped smoking when they received these targeted programs. Overall, quitting smoking during pregnancy can significantly reduce the harmful effects of tobacco on the baby's growth and improve health for both the mother and baby.12367
Who Is on the Research Team?
Natacha De Genna
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
This trial is for pregnant individuals under 26 weeks who speak English, are at least 18 years old, plan to stay pregnant, and have used tobacco or cannabis during pregnancy or shortly before. People using opioids or in opioid treatment can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive an intervention to address prenatal depressive symptoms to encourage quitting tobacco and cannabis during pregnancy
Follow-up
Participants are monitored for abstinence from tobacco and cannabis, and changes in depressive symptoms
What Are the Treatments Tested in This Trial?
Interventions
- Perinatal smoking cessation treatment
Trial Overview
The study tests counseling sessions designed to help pregnant people quit smoking and cannabis use by addressing depression symptoms. The goal is to support quitting during pregnancy and staying smoke-free after birth.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Citations
Smoking Cessation Pharmacotherapy Use in Pregnancy
Although the risk of adverse outcomes can be significantly reduced by quitting in the first half of pregnancy, less than 50% of individuals who ...
“Smoking during pregnancy – Perinatal outcomes, financial ...
An in-depth analysis of the effects of smoking in the antenatal, intrapartum and postnatal periods in comparison to a non-smoking control group.
3.
tobaccoinduceddiseases.org
tobaccoinduceddiseases.org/Smoking-Cessation-in-Pregnancy-An-update-for-maternity-care-practitioners,109906,0,2.htmlSmoking cessation in pregnancy: An update for maternity ...
This paper provides an up-to-date summary of the effects of smoking in pregnancy as well as challenges and best practices for supporting smoking cessation in ...
Cigarette Smoking Among Pregnant Women During ...
Cigarette smoking during pregnancy increases the risk for pregnancy complications and adverse infant outcomes such as preterm delivery, ...
Effectiveness of smoking cessation interventions in ...
Five studies found a statistically significant increase in smoking cessation rates or reduction in tobacco consumed in the intervention group.
Dose–response association between maternal smoking ...
Our finding that smoking cessation after the first trimester of pregnancy significantly reduced the risk of infant all-cause death and ...
7.
contemporaryobgyn.net
contemporaryobgyn.net/view/the-impact-of-smoking-cessation-on-pregnancy-outcomesThe impact of smoking cessation on pregnancy outcomes
Data from the study also found an increased risk of stillbirth among women who continued smoking during pregnancy vs those who never smoked or ...
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