18 Participants NeededMy employer runs this trial

Resisted Walking for Stroke

CG
Overseen ByChristina Garrity, DPT
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Cincinnati
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new method to measure the energy cost of walking in individuals who have had a stroke. Participants walk on a treadmill with and without resistance (resisted walking) to help researchers understand how walking becomes inefficient after a stroke. The goal is to identify the sources of these inefficiencies to potentially enhance independence. The trial seeks individuals who experienced a stroke at least three months ago, have difficulty walking, and can walk on a treadmill for at least five minutes. As an unphased trial, it offers participants the chance to contribute to groundbreaking research that could lead to improved rehabilitation strategies for stroke survivors.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators.

What prior data suggests that this resisted walking protocol is safe for individuals with stroke?

Research has shown that treadmill training, which involves walking with some resistance, is generally safe for people who have had a stroke. Studies have found that this exercise improves both walking speed and distance. Most importantly, participants tolerated it well. These studies reported no major negative effects, suggesting that walking with resistance is a safe option for stroke recovery.12345

Why are researchers excited about this trial?

Researchers are excited about resisted walking as a treatment for stroke recovery because it introduces a unique approach by incorporating resistance into treadmill walking. Unlike traditional physical therapy, which often focuses on improving mobility through standard exercises, resisted walking aims to enhance muscle strength and endurance by adding resistance to movement. This method could potentially accelerate recovery and improve functional outcomes for stroke survivors, offering a novel way to regain mobility more effectively.

What evidence suggests that resisted walking is effective for improving walking impairment in stroke patients?

This trial will compare treadmill walking with and without resistance for stroke survivors. Research has shown that treadmill training can help stroke survivors improve their walking. Specifically, body-weight supported treadmill training (BWSTT) can increase walking speed and stamina. This method effectively supports stroke survivors, enabling easier practice of walking. Additionally, adjusting the difficulty during treadmill training can further enhance walking endurance. Overall, treadmill training offers a promising approach to help individuals regain their walking ability after a stroke.13678

Who Is on the Research Team?

CG

Christina Garrity, DPT

Principal Investigator

University of Cincinnati

Are You a Good Fit for This Trial?

This trial is for adults aged 30-80 who have walking difficulties due to a stroke at least 3 months ago. Participants must be able to walk short distances with or without assistive devices, follow simple instructions, and not have serious heart, lung, or other neurological conditions.

Inclusion Criteria

No contraindications to exercise according to ACSM guidelines
I am between 30 and 80 years old.
I have weakness on one side of my body from a stroke.
See 5 more

Exclusion Criteria

Pregnancy
I have severe muscle stiffness in my lower limbs.
Implanted pacemaker or defibrillator
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Single Session Walking Trials

Participants complete three 5-minute treadmill walking trials, with the third trial against resistance to increase cost of walking

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the walking trials

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Resisted walking

Trial Overview

The study tests how well a new way of measuring the effort needed to walk works in people with chronic stroke. Participants will do treadmill walking trials, including one where they walk against resistance. The results are compared to traditional energy use measurements.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Treadmill walking with and without resistanceExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Cincinnati

Lead Sponsor

Trials
442
Recruited
639,000+

Citations

Effectiveness of Treadmill Training Intervention for the ... - PMC

Studies employing BWSTT show greater improvements in walking outcomes, highlighting the added value of this technique in stroke rehabilitation.

Effectiveness of treadmill assisted gait training in stroke ...

Treadmill training following stroke offers improvement in walking distance. However, it has no significant advantage in improving walking speed and balance ...

Effectiveness of Treadmill Training Intervention for the ...

Conclusion. Treadmill training, particularly when combined with BWSTT, effectively enhances walking speed and endurance in stroke survivors.

Treadmill training is effective for ambulatory adults with stroke

The authors concluded that treadmill training, without body-weight support, improved walking for ambulatory patients after stroke, and this improvement was ...

Challenge Level Contributes to the Efficacy of Treadmill ...

Overall, the findings indicate that, after stroke, some of the efficacy of TT on walking endurance can be explained by the challenge level during training. This ...

The effects of a progressive resistance training program ... - PMC

The purpose of this study was to evaluate the effects of a progressive resistance training (PRT) program on the walking ability of chronic stroke patients.

Systematic Review and Meta-Analysis of Treadmill ...

Conclusions: Treadmill training demonstrated moderate effectiveness for gait rehabilitation in patients with chronic stroke, with dual-task ...

The Effects of Body Weight Supported Treadmill Training ...

The majority of stroke survivors have mobility difficulties such as poor standing, decreased walking speed, balance disturbances, and increased risk for falls.