Cognitive Processing Therapy for Post-Traumatic Stress Disorder

CH
Overseen ByCara Herbitter, PhD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Boston University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Populations facing health disparities include groups with significantly higher rates of posttraumatic stress disorder than the general population who frequently experience lived experience stress, which may complicate posttraumatic stress disorder symptom presentations. However, there are currently no posttraumatic stress disorder treatments designed to meet the unique needs of these individuals.

The proposed study will pilot an adaptation of Cognitive Processing Therapy (a gold-standard treatment for posttraumatic stress disorder) that has been modified to incorporate the impact of lived experience stress as an additional treatment target. This project has the potential to advance our understanding of how to enhance Cognitive Processing Therapy in order to optimize posttraumatic stress disorder treatment response and mitigate health disparities.

Who Is on the Research Team?

CH

Cara Herbitter, PhD, MPH

Principal Investigator

Psychiatry CABUSM and National Center for PTSD, VA Boston Healthcare System

Are You a Good Fit for This Trial?

This trial is for people diagnosed with post-traumatic stress disorder (PTSD), especially those from groups who face extra life stresses or health disparities. Participants should be adults able to take part in therapy sessions.

Inclusion Criteria

Endorsement of SGM stress experiences with moderate distress
Self-identification as a sexual or gender minority (SGM) individual
I have been on the same dose of psychiatric medication for at least one month.
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Exclusion Criteria

Current severe substance use that warrants immediate medical attention
Current active suicidal or homicidal ideation with intent or plan
I do not have an unstable psychotic disorder or current psychosis.
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Cognitive Processing Therapy (CPT)
  • Cognitive Processing Therapy - Lived Experience Adaptation (CPT-LEAP)

Trial Overview

The study compares standard Cognitive Processing Therapy (CPT) with a new version called CPT-LEAP, which adds support for dealing with ongoing life stress. Both are talk therapies aimed at helping PTSD symptoms.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Cognitive Therapy Processing Therapy - Lived Experience Adapted Protocol (CPT--LEAP)Experimental Treatment1 Intervention
Group II: Standard Cognitive Therapy Processing (CPT)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Boston University

Lead Sponsor

Trials
494
Recruited
9,998,000+

National Institute of Mental Health (NIMH)

Collaborator

Trials
3,007
Recruited
2,852,000+