Written Exposure Therapy for PTSD in Substance Use Disorder

(WEST Trial)

RS
KW
Overseen ByKevin Wenzel, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Potomac Health Foundations
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of the current research study is to evaluate the efficacy of the refined Written Exposure in Substance Treatment (WEST) for PTSD among residential SUD patients through a randomized controlled trial. All participants meet criteria for PTSD and are in a short term residential SUD treatment program (target residential treatment duration = 28 days) regardless of the research. Participants will be randomly assigned to WEST + treatment as usual (TAU) or TAU only. The primary outcome is change in PTSD symptoms from pre-intervention to post-intervention. The secondary outcome will be change in SUD outcomes (e.g., treatment completion, reduced opioid and other drug use) and change in non-PTSD mental health outcomes (e.g., depression) from pre-intervention to post-intervention.

Are You a Good Fit for This Trial?

Inclusion Criteria

Be enrolled in residential SUD treatment at MTC
I am 18 years old or older.
Be sufficiently able to speak, read, and write in the English language to complete WEST therapy and study assessments
See 2 more

Exclusion Criteria

Lack of access to a mobile phone after treatment discharge
Presence of any other psychiatric instability or suicidality that would interfere with study participation
Suicide attempt within the past 3 months
See 4 more

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: TAU + Adapted Written Exposure Therapy (WET)Experimental Treatment1 Intervention
Group II: TAUActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Potomac Health Foundations

Lead Sponsor

Trials
7
Recruited
490+

University of Maryland, Baltimore County

Collaborator

Trials
13
Recruited
2,400+