Brain Stimulation + Therapy for PTSD

CS
AF
Overseen ByAmanda Flores, BS
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: The University of Texas Health Science Center at San Antonio
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

In this study, the investigators are evaluating whether transcranial direct current stimulation (tDCS), a brain stimulation technique, can be combined with Written Exposure Therapy (WET), a standard talk therapy for posttraumatic stress disorder (PTSD) to improve treatment response and improve symptom of traumatic brain injury (TBI).

After consenting to be in the study, participants will be asked to complete a baseline assessment of your psychological and physical health that will determine whether you are able to participate in the study. Following the baseline, you will be randomly assigned to receive tDCS or a sham/placebo. Everyone will also participate in 5 weekly WET psychotherapy sessions for 5 consecutive weeks. The first appointment will be 90 minutes and the subsequent appointments will be 60 minutes. tDCS or sham/placebo will occur during the writing portion of the session. All participants will also be asked to complete 1-, 3-, and 6-month posttreatment follow-up assessments.

Who Is on the Research Team?

CS

Casey Straud, PsyD

Principal Investigator

The University of Texas Health Science Center at San Antonio

Are You a Good Fit for This Trial?

Inclusion Criteria

History of mild to moderate Traumatic Brain Injury (TBI)
I have been diagnosed with PTSD by a clinician using the CAPS-5-R scale.
I am a U.S. military service member or veteran between 18 and 70 years old.
See 1 more

Exclusion Criteria

Presence of metallic objects other than dental appliances/fillings above the shoulders
Current suicidal ideation severe enough to warrant immediate attention
I have a history of a major neurological disorder like epilepsy or dementia.
See 10 more

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: tDCS plus WET treatmentExperimental Treatment2 Interventions
Group II: Sham plus WETPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

The University of Texas Health Science Center at San Antonio

Lead Sponsor

Trials
486
Recruited
92,500+

United States Department of Defense

Collaborator

Trials
940
Recruited
339,000+