Culturally Adapted Contingency Management for Stimulant Use Disorder

OJ
AA
Overseen ByAlexander Alario, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Yale University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new approach to assist Black adults with a stimulant use disorder, indicating recent struggles with drugs like cocaine or methamphetamine. The study compares a culturally adapted reward system, called Culturally Adapted Contingency Management, where participants earn incentives for remaining drug-free, against both a basic version of this system and the usual clinic care. The goal is to determine if tailoring treatment to cultural needs enhances effectiveness. Individuals who self-identify as Black or African American and have been diagnosed with stimulant use disorder in the last 30 days may be suitable for this trial. As an unphased trial, this study provides a unique opportunity to contribute to research that could lead to more effective, culturally sensitive treatments.

Do I need to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this culturally adapted contingency management protocol is safe for Black adults with stimulant use disorder?

Past studies have shown that contingency management (CM) is a well-tolerated treatment for people with stimulant use disorder. Research indicates that CM effectively helps individuals stop using stimulants and remains safe for those with other substance use disorders. Participants in various studies have not reported significant negative effects from CM, suggesting the treatment is generally safe.

For the culturally adapted CM, specific safety data is limited. However, adapting CM to fit different cultural backgrounds aims to enhance its relevance and effectiveness without compromising safety. As CM is a behavioral treatment without medication, the risk of physical side effects remains low. This makes CM a promising and safe option for managing stimulant use disorder.12345

Why are researchers excited about this trial?

Researchers are excited about Culturally Adapted Contingency Management (CM) because it personalizes treatment for stimulant use disorder by considering cultural factors that may influence a person's recovery journey. Unlike standard treatments, which often rely on a one-size-fits-all approach, this method tailors the motivational incentives to be culturally relevant, potentially increasing engagement and effectiveness. This innovative approach aims to improve outcomes by respecting and leveraging the diverse backgrounds of participants, which is a significant shift from typical treatment protocols.

What evidence suggests that this trial's treatments could be effective for stimulant use disorder?

Studies have shown that contingency management (CM) effectively treats stimulant use disorder by rewarding positive actions, such as staying drug-free. This trial will compare different CM approaches. Participants in the "Culturally Adapted CM" arm will receive a version of CM tailored to specific cultures. Research suggests this adaptation can be even more effective, especially for communities like Black adults, by incorporating cultural considerations into treatment plans. Meanwhile, participants in the "Basic CM" arm will receive a standard CM program. Evidence from multiple studies supports CM's success in reducing drug use and helping people continue their treatment. Specifically, participants in basic CM programs were 2.4 times more likely to have drug-free tests, demonstrating its clear impact. Overall, CM is a proven method for addressing stimulant use disorder in various groups.23467

Who Is on the Research Team?

OJ

Oluwole Jegede, MD, PhD

Principal Investigator

Yale University

Are You a Good Fit for This Trial?

This trial is for Black or African American adults who have been diagnosed with stimulant use disorder within the past month.

Inclusion Criteria

* participants must self-identify as Black/African American
* DSM-5 diagnosis of stimulant use disorder in the past month (30 days)

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Lead-in Phase

Participants undergo a 4-week lead-in phase before the main treatment begins

4 weeks
Twice weekly visits

Treatment

Participants receive culturally adapted or basic CM over a 12-week period

12 weeks
Twice weekly visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Culturally Adapted Contingency Management

Trial Overview

The study compares two approaches to help people stop using stimulants: a standard rewards-based program (contingency management) and a version specially adapted for Black adults. Participants are randomly assigned to one of these groups.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Group I: Culturally Adapted CMExperimental Treatment1 Intervention
Group II: Basic CMExperimental Treatment1 Intervention
Group III: Standard Care ConditionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Yale University

Lead Sponsor

Trials
1,963
Recruited
3,046,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

A randomized controlled trial of contingency management for ...

Participants assigned to contingency management experienced significantly lower levels of alcohol use, injection drug use, psychiatric symptoms, and were five ...

Contingency Management for Stimulant Use Disorder

CM sessions and substance use outcomes. Drug and. Alcohol Dependence ... Long-term efficacy of contingency management treat- ment based on objective ...

Data-Driven Contingency Management Incentive Magnitudes

This report provides contemporary weekly incentive magnitude estimates that can be used to calculate total incentive magnitude for protocols of custom ...

Contingency Management for Stimulant Use Disorder Health ...

We identified 17 publications from 17 eligible trials with effectiveness outcomes and 6 relevant ongoing trials. Studies varied widely in design and ...

Long-Term Efficacy of Contingency Management Treatment ...

Among 18 moderators, longer length of active treatment was found to significantly improve long-term abstinence. Conclusions: CM showed long-term benefit in ...

Contingency management for stimulant use disorder and ...

The primary outcome is mortality in the year following the index CM visit. All-cause mortality data was obtained from the National Death Index and linked to ...

Contingency Management Fact Sheet

Moreover, nine meta-analyses performed during the past two decades used the combined data from multiple studies to find positive results from contingency.