Peer-Support Group for Psychosis

(VVV RCT Trial)

Not yet recruiting at 1 trial location
IA
EH
Overseen ByErica H Fletcher, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: VA Office of Research and Development
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help veterans with schizophrenia spectrum disorders who experience psychosis improve their social lives and reduce distress. It tests two peer-led support programs: Veteran Voices and Visions (VVV), specifically designed for psychosis, and Wellness Recovery Action Planning (WRAP), a broader recovery program. The trial will compare how these programs affect feelings of distress, social belonging, and functioning. Veterans who have experienced weekly auditory hallucinations (hearing things that aren't there) for at least six months and can participate in group discussions might be a good fit.

As an unphased trial, this study offers veterans a unique opportunity to contribute to research that could enhance support programs for others facing similar challenges.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that these peer-support group interventions are safe for Veterans with psychosis?

Research has shown that the Veteran Voices and Visions (VVV) support groups are generally safe for participants. This program, designed for veterans with serious mental illness, helps reduce stress related to psychosis without major safety concerns. Participants typically join these group sessions without experiencing negative effects.

For Wellness Recovery Action Planning (WRAP), studies have indicated that it is a well-tolerated program. This peer-led approach helps people manage their recovery and improve their quality of life. Evidence suggests that participants rarely report negative side effects.

In summary, both VVV and WRAP are considered safe, with no major safety issues reported in previous studies.12345

Why are researchers excited about this trial?

Researchers are excited about the Peer-Support Group for Psychosis trial because it explores innovative, non-medication-based interventions that target serious mental illness. Veteran Voices and Visions (VVV) is distinctive because it adapts the Hearing Voices approach, focusing on normalizing and creating community around psychotic symptoms like hallucinations and delusions, which is not a focus of typical treatments like antipsychotic medications. Wellness Recovery Action Planning (WRAP), on the other hand, is a structured self-management program led by peers that aims to improve quality of life and subjective recovery, although it's not tailored specifically for psychosis. Both approaches prioritize peer support and personal empowerment, offering new pathways for recovery beyond traditional medical treatments.

What evidence suggests that this trial's treatments could be effective for psychosis?

This trial will compare two peer-support interventions for Veterans with serious mental illness. Research has shown that the Veteran Voices and Visions (VVV) group, one of the interventions in this trial, can help reduce the distress Veterans experience from psychosis. This support helps Veterans feel more socially connected by normalizing symptoms like hearing voices. Previous findings suggest that VVV can also increase feelings of belonging, helping Veterans with serious mental illness feel less alone.

The other intervention in this trial is Wellness Recovery Action Planning (WRAP). Studies have shown that WRAP reduces overall distress from psychiatric symptoms and improves quality of life for people with serious mental illness. It focuses on self-management and recovery, increasing hope and empowerment. However, WRAP is generally not specifically designed for psychosis.12678

Who Is on the Research Team?

IA

Ippolytos A Kalofonos, MD PhD MPH

Principal Investigator

VA Greater Los Angeles Healthcare System, West Los Angeles, CA

MJ

Matthew J Chinman, PhD

Principal Investigator

VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

Are You a Good Fit for This Trial?

This trial is for veterans who speak English and have been hearing voices at least once a week in the past 6 months (not just from substance use). They must be able to give consent. People with major brain injuries, dementia, certain seizure disorders, or those unable to consent can't join.

Inclusion Criteria

English fluency sufficient for participating in groups
I have heard voices at least once a week in the past 6 months, not from substance use.
Able to provide consent

Exclusion Criteria

Clinically significant seizure disorder, traumatic brain injury, dementia, developmental disorder/intellectual disability
Psychosis exclusively due to substance use
Inability to provide informed consent for any reason, including due to acute psychosis, mania, or dementia, or active guardianship or durable power of attorney
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either the Veteran Voices and Visions (VVV) or Wellness Recovery Action Planning (WRAP) intervention for 12 weeks

12 weeks
Weekly group sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 weeks
Assessments at 12 and 24 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Veteran Voices and Visions (VVV)
  • Wellness Recovery Action Planning (WRAP)

Trial Overview

The study compares two peer-led support groups: Veteran Voices and Visions (VVV), which focuses on coping with psychosis and building social connections, versus Wellness Recovery Action Planning (WRAP), another group program. The goal is to see which helps more with distress from hearing voices and social functioning.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Veteran Voices and Visions (VVV)Experimental Treatment1 Intervention
Group II: Wellness Recovery Action Planning (WRAP)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

VA Office of Research and Development

Lead Sponsor

Trials
1,691
Recruited
3,759,000+

VA Pittsburgh Healthcare System

Collaborator

Trials
36
Recruited
15,900+

Citations

Impact of Veteran Voices & Visions Peer Support Groups ...

We will run the study using the full collection of outcome measures (such as reduced distress due to psychosis, self-efficacy, and social ...

Testing a Peer-Support Group for Veterans Who Hear Voices

Veteran Voices and Visions (VVV) is a psychosocial, peer-led group intervention for Veterans with psychosis based that reduces distress related ...

NCT05562674 | Impact of VVV Group for Veterans With SMI

VVV targets Veterans with SMI who experience psychosis, a group particularly in need of support with social integration. Virtual VVV groups are co-led by VA ...

Impact of VVV Group for Veterans With SMI | Clinical Trial

VVV targets Veterans with SMI who experience psychosis, a group particularly in need of support with social integration. Virtual VVV groups are ...

A pilot trial examining the effects of veteran voices and ...

Aims: This paper describes the effects of participation in Veteran Voices and Visions (VVV) groups, an adaptation of the HV approach, co-led by clinicians and ...

Mariam Nazinyan's research works | VA Greater Los ...

A pilot trial examining the effects of veteran voices and visions, an adaptation of hearing voices groups for a large public health system in the United States.

Project Details

... Veteran Voices and Visions” (VVV). VVV targets Veterans with SMI who experience psychosis, a group particularly in need of support with social integration.

Support Group for Veterans with Psychosis (VVV Trial)

Research has shown that the Veteran Voices and Visions (VVV) support groups are generally safe for participants. ... serious mental illness to openly ...