LIFT-UP Chatbot for Smoking Cessation

(LIFT-UP Trial)

LP
Overseen ByLindsey Potter, MPH, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Utah
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new chatbot designed to help people quit smoking, focusing on those in areas with persistent poverty. The researchers aim to understand how digital tools can support smoking cessation by identifying what works best for individuals in these communities. Participants will share their experiences and preferences through interviews to help refine the LIFT-UP Chatbot. Those who smoke at least three cigarettes a day, wish to quit soon, and live in a low-income area might be a good fit for this study.

As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could significantly impact smoking cessation strategies in underserved communities.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the LIFT-UP Chatbot is safe for smoking cessation?

Research has shown that AI chatbots designed to help people quit smoking are generally well-received. In past studies, participants expressed satisfaction with these tools. For instance, one study found that most users were happy with the support an AI chatbot provided in their efforts to quit smoking. Additionally, users interacted with the chatbot frequently, indicating it was easy to use and helpful.

Another study used a chatbot for short conversations over several weeks in a smoking cessation program. This method successfully kept users engaged without causing major problems. Overall, these findings suggest that AI chatbots, like the LIFT-UP Chatbot, are promising tools that are safe and comfortable for people trying to quit smoking.12345

Why are researchers excited about this trial?

The LIFT-UP Chatbot is unique because it offers a digital approach to smoking cessation, using an interactive chatbot to assist users. Unlike traditional methods like nicotine patches, gum, or counseling sessions, this chatbot provides real-time support and guidance through a HIPAA-compliant videoconferencing platform. Researchers are excited about this treatment because it leverages technology to make quitting smoking more accessible and personalized, potentially reaching a broader audience and offering support whenever needed. This could revolutionize how people access smoking cessation resources, especially for those who may not have easy access to in-person treatments.

What evidence suggests that the LIFT-UP Chatbot is effective for smoking cessation?

Research has shown that chatbots can help people quit smoking. In one study, a chatbot called QuitBot engaged nearly all participants for three months and demonstrated promising results in aiding smoking cessation. Other studies also indicate that chatbots can encourage smoking cessation, particularly when they employ motivational techniques. This trial will evaluate the LIFT-UP Chatbot, which may effectively assist individuals in quitting smoking, especially those with limited access to other resources.46789

Who Is on the Research Team?

CS

Chelsey Schlechter, MPH, PhD

Principal Investigator

Huntsman Cancer Institute

CM

Christian Mahony Reategui Rivera, MD, MS

Principal Investigator

University of Utah

Are You a Good Fit for This Trial?

This trial is for people who smoke and live in areas with persistent poverty. Participants should be willing to talk about their experiences with quitting smoking, digital access, and health needs.

Inclusion Criteria

I am 18 years old or older.
Motivated to quit in the next 30 days
Have a computer or tablet with internet access for 1:1 interviews
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Moderated Session

Participants will attend a ~80 minute moderated 'think-aloud' session via HIPAA compliant videoconferencing platform

1 day
1 session (virtual)

Follow-up

Participants are monitored for usability, acceptability, and cultural fit of the intervention

1 day

What Are the Treatments Tested in This Trial?

Interventions

  • LIFT-UP Chatbot

Trial Overview

The study is testing a new multilingual chatbot called LIFT-UP that helps people quit smoking. Researchers will interview participants to learn how well the chatbot meets their needs and what could make it better.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Moderated SessionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Utah

Lead Sponsor

Trials
1,169
Recruited
1,623,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Huntsman Cancer Institute

Collaborator

Trials
14
Recruited
7,700+

Citations

Efficacy of a conversational chatbot for cigarette smoking ...

The pilot RCT proved feasible, achieving a 96% retention rate for outcome data at 3 months. QuitBot showed strong user engagement and promising cessation rates ...

LLM Intervention for Tobacco in Underserved Populations ...

This study will test a tailored, multilingual tobacco cessation chatbot called LIFT-UP ), designed to better meet the needs of people living in ...

Conversational Chatbot for Cigarette Smoking Cessation

In a pilot RCT with 96% three-month outcome data retention, QuitBot demonstrated high user engagement and promising cessation rates compared to the National

Mixed Methods Study Comparing Motivational Interviewing ...

The results confirmed that chatbots are a promising tool in motivating smoking cessation and the use of MI can improve user experience.

Chatbots for Smoking Cessation: Scoping Review.

This scoping review aims to assess the extent of research in the chatbot literature for smoking cessation and provide recommendations for future ...

AI-Enabled Personalized Smoking Cessation Intervention ...

This feasibility study evaluated the implementation of an evidence-based smoking cessation counseling session delivered by a GenAI-powered chatbot, Aipaca. We ...

Chatbot for Online Support Groups to Treat Tobacco ...

Smart phone with unlimited data; 100 cigarettes lifetime; Prepared to quit smoking within 10 days of study start; Active text and email; Use of social media or ...

Focus Group Study of End Users and Smoking Cessation ...

Quin is a prototype chatbot that aims to improve access to personalized, evidence-based smoking cessation information and support via an app.

GW Study Shows Promise for AI Chatbots in Smoking ...

The research revealed that most participants were satisfied with the tool, indicating that AI chatbots could enhance existing smoking cessation ...