Mindfulness-Based Intervention for Smoking Cessation
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a mindfulness program called MBRP-SA to help cancer survivors quit smoking and reduce risky alcohol use. Participants will either attend online mindfulness sessions or receive assistance from the Florida Tobacco Quitline, with additional support for alcohol use. It is ideal for Florida cancer survivors who have recently smoked, experienced a binge drinking episode, and wish to quit smoking within the next month. As an unphased trial, this study provides a unique opportunity for participants to contribute to innovative research that could enhance health outcomes for cancer survivors.
Do I have to stop taking my current medications for the trial?
The trial requires that you are not currently using any tobacco cessation medications or treatments to quit smoking. Other medications are not mentioned, so it's best to discuss with the trial team.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research shows that Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) is safe. Studies have found no side effects or harmful events linked to this mindfulness treatment. Participants experienced no negative effects from the mindfulness sessions. Overall, the treatment is easy to handle, making it a promising choice for those wanting to reduce smoking and alcohol use.12345
Why are researchers excited about this trial?
Researchers are excited about the Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) because it offers a fresh approach compared to traditional methods like nicotine replacement therapies or prescription medications. This treatment focuses on mindfulness techniques, helping individuals become more aware of their cravings and responses, which can lead to better self-control and reduced relapse rates. Delivered via Zoom in a group format, it also provides increased accessibility and convenience, making it easier for participants to engage consistently. Additionally, the Quitline Support arm connects participants to the Florida Tobacco Quitline, offering personalized support and community referrals, which complements the mindfulness approach and enhances overall support for smoking cessation.
What evidence suggests that this trial's treatments could be effective for smoking cessation and alcohol use?
This trial will compare Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) with Quitline Support for smoking cessation. Studies have shown that MBRP-SA can help people quit smoking and reduce alcohol consumption. One large study found that MBRP led to fewer days of heavy drinking compared to traditional cognitive-behavioral therapy (CBT). Another study showed that MBRP was equally effective as CBT in reducing risky drinking and smoking. Research also suggests that MBRP can significantly lower the chance of returning to substance use and heavy drinking compared to usual treatments. These findings support MBRP-SA as a promising method for quitting smoking and reducing alcohol use.26789
Who Is on the Research Team?
Christine Vinci, PhD
Principal Investigator
Moffitt Cancer Center
Are You a Good Fit for This Trial?
This trial is for adults in Florida who have had cancer, currently smoke at least one cigarette a day, and drink more than recommended or binge drink. Participants must want to quit smoking and cut back on alcohol soon, speak English, and not be pregnant or in hospice care.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) via Zoom or Quitline Support for smoking cessation and community referrals for alcohol use treatment
Follow-up
Participants are monitored for smoking abstinence and alcohol use outcomes
What Are the Treatments Tested in This Trial?
Interventions
- MBRP-SA
Trial Overview
The study compares a mindfulness-based program (MBRP-SA) designed to help people avoid returning to smoking and heavy drinking with standard Quitline support. Participants are randomly assigned to either group.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Participants randomized to this condition will be connected to the Florida Tobacco Quitline for smoking cessation services, as well as receive community referrals for alcohol use treatment.
Participants randomized to this condition will receive a mindfulness-based intervention delivered in a group format via Zoom.
Find a Clinic Near You
Who Is Running the Clinical Trial?
H. Lee Moffitt Cancer Center and Research Institute
Lead Sponsor
Florida Biomedical Research Program - James & Esther King
Collaborator
Citations
Pilot Randomized Controlled Trial of Mindfulness-Based ...
One large-scale study found that Mindfulness-Based Relapse Prevention (MBRP) resulted in fewer heavy drinking days through 12 months than CBT (Bowen et al., ...
Effectiveness of Mindfulness-Based Relapse Prevention ...
This article presents results from a pilot trial evaluating the feasibility and initial efficacy of Mindfulness-Based Relapse Prevention (MBRP)
Pilot randomized controlled trial of mindfulness-based ...
In sum, MBRP-SA had comparable outcomes to CBT on all metrics measured. Future research should evaluate the efficacy of MBRP-SA on smoking ...
4.
psychiatry.wisc.edu
psychiatry.wisc.edu/wp-content/uploads/2025/05/Article-1_Bowen-et-al-JAMA-2014.pdfRelative Efficacy of Mindfulness-Based Relapse ...
substance use disorders, RP and MBRP, compared with TAU, produced significantly reduced relapse risk to drug use and heavy drinking. Relapse ...
Research
The study provides preliminary data for future studies examining both mechanisms and effectiveness of mindfulness-based interventions for cigarette smoking.
Mindfulness-Based Relapse Prevention for Substance Use ...
The MBRP intervention appears safe as indicated by lack of reported side effects or adverse events. Significant decreases were found in overall days of ...
Mindfulness-Based Intervention for Smoking Cessation
This study will examine the efficacy of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) compared to standard care ...
Mindfulness-based Relapse Prevention for Substance Use ...
We have limited confidence in estimates suggesting MBRP yields small effects on withdrawal/craving and negative consequences versus comparator interventions.
A Mindfulness Based Application for Smoking Cessation
Mindfulness based smoking therapy (MT) has preliminary support for reducing consumption in smokers, and Dr. Judson Brewer has recently translated this program ...
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