318 Participants NeededMy employer runs this trial

Mobile Enhanced Prevention Support for HIV Prevention and Substance Use Disorder

Recruiting at 2 trial locations
SD
Overseen ByStudy Director
Age: 18 - 65
Sex: Male
Trial Phase: Academic
Sponsor: University of California, Los Angeles
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if the Mobile Enhanced Prevention Support (MEPS) program can effectively assist people with substance use disorders in various community settings. MEPS increases the use of HIV prevention methods and other health services through peer mentoring, a smartphone app, and incentives for attending medical appointments. Participants will receive either the MEPS program or standard care to evaluate which is more effective. This trial is ideal for individuals assigned male at birth, released from incarceration within the last year, who have a substance use disorder, and own or plan to obtain a smartphone. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance community health support systems.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that the MEPS intervention is safe for participants?

A previous study found the Mobile Enhanced Prevention Support (MEPS) program safe for individuals recently released from jail with substance use disorders. Research shows that participants received the program, which includes a mobile app, meetings with a peer mentor, and rewards for using services, positively. No major negative effects were reported.

The MEPS system has previously helped individuals increase their use of HIV prevention services and treatments for substance use disorders. Findings suggest that participants generally accepted the program, found it easy to use, and integrated it well into their daily lives.

Overall, evidence suggests that MEPS is a safe option for individuals with similar backgrounds and needs. Participants have used it without any serious safety concerns, making it a promising choice for those seeking to increase their access to health services and support.12345

Why are researchers excited about this trial?

Researchers are excited about the Mobile Enhanced Prevention Support (MEPS) because it offers a novel approach to managing HIV prevention and substance use disorder. Unlike traditional treatments that may rely mainly on medication or counseling alone, MEPS combines technology with personal support. Participants receive a smartphone app to track goals, manage incentive earnings, and find providers, plus 14 sessions with a peer mentor over six months. This tech-driven, personalized support system aims to enhance engagement and accessibility, potentially leading to better health outcomes.

What evidence suggests that the MEPS intervention is effective for HIV prevention and substance use disorder?

Research has shown that the Mobile Enhanced Prevention Support (MEPS) program effectively helps prevent HIV. In this trial, participants in the MEPS arm will receive a client-centered goal planning session, 14 sessions with a peer mentor over six months, cash incentives for accessing services, and a smartphone app to track goals and appointments. Studies have found that MEPS increased the use of PrEP, a medication that prevents HIV, among people with substance use issues who recently left jail. This program uses peer support, a mobile app, and rewards to encourage people to use medical services. In Los Angeles County, MEPS improved HIV prevention and related health check-ups. Evidence suggests MEPS is a promising way to boost HIV testing and PrEP use in at-risk groups.13467

Are You a Good Fit for This Trial?

This trial is for adults aged 18-59 who were assigned male at birth, have a history of drug use or injection, were released from jail in the past year, plan to stay in certain California counties for at least 9 months, do not have HIV, and own or will get a smartphone. Participants must be able to read and speak English.

Inclusion Criteria

In the past 24 months, I have had sex with a man or used injection drugs.
Has not received an HIV diagnosis (based on self-report)
Plans to reside within designated jurisdictions (counties) for the 9 months following enrollment
See 7 more

Exclusion Criteria

RCT Participants who have insufficient reading skills to operate a mobile application on a cell phone
I do not speak or understand English.
I do not have a smartphone and am not willing to get one.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Client-centered Planning Session

All participants receive a client-centered planning session following enrollment, conducted by phone, video, or in person.

1 session
1 visit (in-person or virtual)

Treatment

Participants in the intervention arm receive the MEPS intervention, including 14 sessions with a peer mentor over 6 months, cash incentives, and use of the GeoPass app.

6 months
14 sessions (in-person or virtual)

Follow-up

Participants are monitored for effectiveness and adherence to PrEP, HIV testing, and SUD service utilization at 6 and 12 months.

12 months
2 visits (in-person or virtual) at 6 and 12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Mobile Enhanced Prevention Support (MEPS)

Trial Overview

The study compares usual care with the Mobile Enhanced Prevention Support (MEPS) program—a support system using peer mentors, planning sessions, incentives, and a mobile app—to help people recently released from incarceration access HIV prevention and substance use services.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: MEPS ArmExperimental Treatment1 Intervention
Group II: Control ArmActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, Los Angeles

Lead Sponsor

Trials
1,594
Recruited
10,430,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

University of California, Berkeley

Collaborator

Trials
193
Recruited
716,000+

Charles Drew University of Medicine and Science

Collaborator

Trials
54
Recruited
8,500+

Starting Over, Inc

Collaborator

Kindful Restoration

Collaborator

CAL-PEP

Collaborator

Citations

Mobile-Enhanced Prevention Support Study for Men ... - PMC

The purpose of this study is to test a new intervention—Mobile-Enhanced Prevention Support (MEPS)—that involves a GPS-based mobile app called GeoPassport ...

Mobile Enhanced Prevention Support for People Leaving Jail

This study will provide HIV prevention and related support services to men who have sex with men and transgender women who have substance use disorders and ...

Mobile enhanced prevention support for people leaving jail

Peer navigation support has shown efficacy among individuals living with HIV [17] as well as those at risk of HIV transmission [18]. Peer interventions have ...

California MEPS Hub

The Mobile Enhanced Prevention Support (MEPS) intervention combines three evidence-based components - peer support, a smartphone app (GeoPass), ...

6.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/32959786/

Mobile-Enhanced Prevention Support Study for Men Who ...

The MEPS study will examine the acceptability and feasibility of combining peer mentor services with a mobile app to facilitate service ...

Mobile Enhanced Prevention Support for HIV ...

MEPS is an evidence-based intervention for people with substance use disorders (SUD) that incorporates a client-centered planning session ...