Pre-op Exercise for Scoliosis

Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Eric Parent
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether specific exercises before surgery can improve outcomes for teenagers with adolescent idiopathic scoliosis, a spine condition causing side-to-side curvature. Researchers aim to determine if these exercises can prevent the curve from worsening and enhance the surgery's effectiveness, speed, and cost-efficiency. Participants will be divided into two groups: one will continue with usual care, while the other will add a daily exercise routine (Pre-op Exercise Program). This trial suits teens aged 10 to 18 with scoliosis and a curve angle over 40 degrees who are awaiting surgery at the Stollery Hospital. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance surgical outcomes for future patients.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this pre-op exercise program is safe for adolescents with scoliosis?

Research has shown that exercises before scoliosis surgery in teenagers are generally safe and manageable. Studies have found that these exercises can improve recovery after surgery, resulting in less pain and shorter hospital stays. For instance, one study found that participants who exercised before surgery experienced fewer complications, with a rate of 5.2% compared to 18.5% for those who did not exercise. This suggests that pre-surgery exercises might not only be safe but could also aid recovery. No reports of major problems have emerged from performing these exercises before scoliosis surgery. Thus, the evidence suggests these exercises are a safe option for those considering joining the trial.12345

Why are researchers excited about this trial?

Unlike the standard of care for adolescent idiopathic scoliosis (AIS), which typically involves surgical interventions and bracing, the pre-op exercise program offers a proactive approach. This program is designed to enhance spinal flexibility and potentially slow the progression of scoliosis before surgery. Researchers are excited because it could improve surgical outcomes and reduce recovery times, offering a non-invasive way to complement existing treatment strategies.

What evidence suggests that pre-op exercises might be an effective treatment for adolescent idiopathic scoliosis?

Research has shown that exercises before surgery can benefit young people with adolescent idiopathic scoliosis. In this trial, participants in the Pre-op Exercise Intervention Group will follow a pre-op exercise program designed to increase spinal flexibility and reduce scoliosis progression, in addition to the standard of care. Studies have found that these exercises can enhance physical ability and stamina. They also suggest that exercise might shorten hospital stays and reduce post-surgery pain. Some evidence indicates that exercise can slow scoliosis progression and might even be as effective as wearing a brace. Overall, pre-surgery exercises could improve outcomes and recovery for adolescents undergoing scoliosis surgery.12356

Are You a Good Fit for This Trial?

This trial is for adolescents aged 10-18 with adolescent idiopathic scoliosis, a spine curve over 40 degrees, and who are waiting for spinal fusion surgery at Stollery Hospital. Those already doing scoliosis-specific exercises or who've had prior surgeries can't join.

Inclusion Criteria

Curve angle >40 degrees
I am on the waitlist for posterior spinal fusion surgery at the Stollery Hospital.
I have been diagnosed with adolescent idiopathic scoliosis.
See 1 more

Exclusion Criteria

Current use of scoliosis-specific exercises
I have had surgery before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pre-operative Exercise Intervention

Participants in the intervention group perform scoliosis-specific exercises for 30 minutes daily to improve flexibility and reduce curve progression before surgery.

6 months
Clinic visits every 3 months for ultrasound imaging and questionnaires

Surgery

Participants undergo surgery for adolescent idiopathic scoliosis, with outcomes measured such as number of vertebrae fused and surgery duration.

Follow-up

Participants are monitored for safety and effectiveness after surgery, including quality of life assessments and appearance questionnaires.

6 weeks post-op
First routine follow-up post-surgery

What Are the Treatments Tested in This Trial?

Interventions

  • Pre-op Exercise Program

Trial Overview

The study compares standard care to adding daily pre-op scoliosis-specific exercises before surgery. Researchers want to see if these exercises improve surgical outcomes like less extensive surgery, better curve correction, shorter hospital stays, and lower costs.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Pre-op Exercise InterventionExperimental Treatment1 Intervention
Group II: Standard of Care (Control)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Eric Parent

Lead Sponsor

Women and Children's Health Research Institute, Canada

Collaborator

Trials
18
Recruited
24,800+

Citations

1.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/42053791/

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