38 Participants NeededMy employer runs this trial

Compassion-Focused Cognitive Behavioural Therapy for Psychosis

(REFLECT Trial)

JD
Overseen ByJessica D'Arcey, PhD Candidate
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Toronto
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if Compassion-Focused Cognitive Behavioural Therapy (REFLECT), a special type of group therapy, can assist people with psychosis by altering core beliefs that might influence their condition. Conducted online over six weeks, the therapy includes weekly sessions and home practice. It targets individuals with schizophrenia, schizoaffective disorder, or similar conditions who are already receiving outpatient treatment. Participants need access to technology such as a smartphone or computer with internet connectivity. The trial will assess the safety, feasibility, and effectiveness of this therapy in improving symptoms and personal recovery. As an unphased trial, it presents a unique opportunity to explore a promising therapy that could enhance personal recovery and symptom management.

Will I have to stop taking my current medications?

The trial does not specify whether you need to stop taking your current medications. However, since participants must be engaged in current outpatient treatment, which can include medication management, it seems likely that you can continue your current medications.

What prior data suggests that this therapy is safe for participants?

Research has shown that Cognitive Behavioral Therapy for psychosis (CBTp) is generally safe and well-tolerated. Studies have found that CBTp can help reduce symptoms like hallucinations and delusions, suggesting that the therapy does not cause significant harm to participants.

Compassion-focused therapy, an important part of this trial, is also considered safe. Previous research indicates it can improve emotional well-being and reduce stress without major side effects. Using these therapies together in a group setting aims to enhance safety and provide emotional support.

Although this trial is new, other studies have demonstrated the safety of these therapies. Participants can expect a supportive and low-risk experience.12345

Why are researchers excited about this trial?

Compassion-Focused Cognitive Behavioural Therapy for psychosis is unique because it integrates skills and strategies specifically designed to foster self-compassion within the traditional CBT framework. Unlike standard treatments for psychosis, which often focus primarily on medication and symptom management, this approach aims to address the emotional and psychological needs of individuals by enhancing their self-compassion. Researchers are excited because this method has the potential to improve mental health outcomes by reducing self-criticism and enhancing emotional resilience, offering a more holistic approach to managing psychosis.

What evidence suggests that this therapy might be an effective treatment for psychosis?

Research has shown that Cognitive Behavioral Therapy for psychosis (CBTp) can reduce symptoms like delusions and hallucinations. Studies indicate it has a small to medium impact on improving overall symptoms of psychosis. Compassion-Focused Therapy (CFT) also shows promise by boosting self-kindness, decreasing self-criticism, and enhancing treatment outcomes. These therapies address the core beliefs contributing to psychosis, aiming to change negative thought patterns. Overall, both CBTp and CFT can lead to meaningful improvements for people experiencing psychosis. In this trial, all participants will undergo a six-week group intervention that integrates these therapies within a CBTp framework.34678

Who Is on the Research Team?

MW

Micheal W Best, PhD

Principal Investigator

University of Toronto

SA

Sean A Kidd, PhD

Principal Investigator

University of Toronto

Are You a Good Fit for This Trial?

This trial is for adults over 18 who have schizophrenia or a related disorder, are currently experiencing psychotic symptoms, are receiving outpatient mental health care, and have access to a smartphone, tablet, or computer with internet.

Inclusion Criteria

I am over 18 years old.
I am currently receiving outpatient treatment for psychosis.
5. Has or has access to personal technology (e.g., smartphone, tablet, or laptop/computer) with access to wifi or cellular data.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 day
1 visit (in-person)

Baseline

Pre-intervention assessments are conducted

2 weeks
1 visit (in-person)

Treatment

Participants undergo a 6-week group therapy intervention with weekly 2-hour sessions delivered via video conferencing

6 weeks
6 visits (virtual)

Post-intervention

Assessments conducted to evaluate changes post-treatment

2 weeks
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

3 months
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • REFLECT

Trial Overview

The study tests a new 6-week group therapy program (REFLECT) delivered online. The therapy focuses on helping people with psychosis examine and change their core beliefs through weekly video sessions and home practice. All participants receive the intervention; there is no comparison group.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Active Group TherapyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Toronto

Lead Sponsor

Trials
739
Recruited
1,125,000+

Citations

Comparative Effectiveness of Cognitive Behavioral Therapies ...

Background: Cognitive behavioral therapy (CBT) has shown consistent efficacy in individuals with psychosis, as supported by many trials.

Meta-analysis and Meta-regression of Cognitive Behavioral ...

Findings indicate small-to-medium effects of CBTp for psychotic symptoms, with increasing effectiveness across time for delusions.

Cognitive Behavioural Therapy for Psychosis: A Health ... - PMC

Compared with any control, CBT for psychosis significantly improved overall psychotic symptoms, positive symptoms, auditory hallucinations, delusions, and ...

The effectiveness of compassion focused therapy with ...

Findings suggested that CFT was effective in improving compassion-based outcomes and clinical symptomology from baseline to post-intervention and compared to ...

Cognitive behavioural therapy for psychosis: The end of the ...

A great many trials have reported that CBTp leads to reductions in psychotic experiences and associated distress and disability. However, other ...

Cognitive Behavior Therapy for Psychosis (CBTp)

CBT is an evidence-based psychological therapy that has been shown to have small to medium effects in improving outcomes for people experiencing psychosis.

Study Details | NCT07569471 | REFLECT: A Novel Group- ...

The investigators hypothesize that this intervention will be safe and feasible, and that we will see improvements in maladaptive core beliefs.

A Narrative Review of Compassion Focused Therapy ... - PMC

CFT was used for diverse PMH outcomes, and the effects were overall positive. Self-compassion and compassion were the most frequently evaluated outcomes.