Prebiotic Sodas for Satiety

This trial examines how different types of prebiotic sodas affect feelings of fullness and digestion in healthy adults. Researchers aim to determine how these sodas alter levels of hormones related to satiety and the rate at which food moves through the stomach. Participants will consume either a regular soda or one of three different prebiotic sodas. Ideal candidates are healthy adults with a stable weight, without severe food allergies or a history of diabetes. As an unphased trial, participants can help advance understanding of the benefits of prebiotic sodas on digestion and fullness.

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on certain medications like GLP-1 receptor agonists, warfarin, or certain supplements. It's best to discuss your specific medications with the study team.

Research has shown that prebiotic sodas are generally safe for most people. These drinks contain fiber that can improve gut health and are usually well-tolerated in moderate amounts. However, some individuals might experience mild side effects like gas or bloating, especially with high consumption. This occurs because gut bacteria break down the fiber in the sodas, producing gas.

Researchers are excited about prebiotic sodas for satiety because they offer a unique approach by incorporating prebiotics, which are dietary fibers that nourish beneficial gut bacteria, potentially enhancing feelings of fullness. Unlike standard appetite control measures like fiber supplements or appetite suppressants, these sodas come in easy-to-consume beverage form, making them more convenient and enjoyable. The addition of a functional ingredient in some versions further sets them apart by potentially boosting their effectiveness in promoting satiety compared to traditional options.

This trial will compare different formulations of prebiotic sodas with a control soda. Research has shown that prebiotic sodas can affect satiety and influence hormones that control hunger. Some studies found that these drinks may increase the release of hormones like GLP-1 and PYY, which help manage appetite. Additionally, prebiotic sodas might help lower blood sugar levels after meals. Other reports suggest that the fiber in these sodas could aid digestion and reduce bloating. While results can vary from person to person, these sodas are generally considered safe and may offer some digestive benefits.⁶⁷⁸⁹¹⁰