32 Participants NeededMy employer runs this trial

Respiratory Muscle Training for Cognitive Performance

BJ
Overseen ByBlair Johnson
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Indiana University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if Inspiratory Muscle Training, which strengthens the muscles used for breathing, can also enhance cognitive function, particularly under challenging breathing conditions. Participants will engage in either actual breathing exercises or a placebo version to compare outcomes. Individuals who have never attempted these exercises, have no respiratory or heart conditions, and can access a smartphone or tablet may qualify. As an unphased trial, this study provides a unique opportunity to explore innovative methods for improving cognitive function through breathing exercises.

What prior data suggests that inspiratory muscle training is safe?

Research has shown that inspiratory muscle training (IMT) is generally safe. Studies indicate that most participants tolerate it well. For instance, these training programs have helped many strengthen their breathing muscles and improve endurance. Reports from these studies often mention few, if any, serious side effects. Some participants might experience minor muscle soreness, similar to regular exercise. Overall, evidence suggests that IMT is a safe method to improve breathing and may also enhance mental performance.12345

Why are researchers excited about this trial?

Inspiratory Muscle Training (IMT) is unique because it targets the respiratory muscles to potentially enhance cognitive performance. Traditional treatments for cognitive issues often rely on medications that target brain chemistry or function, but IMT uses physical training to strengthen the muscles you use to breathe, which could improve oxygen flow to the brain. Researchers are excited about this technique because it offers a non-invasive, drug-free alternative that could complement or enhance existing cognitive therapies. This approach could be particularly beneficial for individuals looking to boost cognitive function without medication side effects.

What evidence suggests that inspiratory muscle training is effective for improving cognitive performance?

Studies have shown that inspiratory muscle training (IMT) strengthens breathing muscles and reduces tiredness. While researchers continue to explore its impact on cognitive skills, some studies suggest it might also enhance mental performance. This trial will compare Active IMT with Sham IMT to evaluate their effects on cognitive performance. IMT has proven to improve lung function and increase exercise capacity, which might also support better brain function. Additionally, stronger inspiratory muscles have been linked to better overall health. Current evidence highlights the potential of IMT to benefit both body and mind.13678

Who Is on the Research Team?

BJ

Blair Johnson, PhD

Principal Investigator

Indiana University

Are You a Good Fit for This Trial?

This trial is for adults aged 18-40 with a BMI under 30, healthy lung function, and no prior experience with inspiratory muscle training. Participants need to have access to a smartphone or tablet with internet.

Inclusion Criteria

I am between 18 and 40 years old.
* Body mass index \<30 kg/m2
I have never received immunomodulatory therapy (IMT).
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo inspiratory muscle training or sham training to assess effects on cognitive performance

8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Inspiratory Muscle Training

Trial Overview

The study tests whether exercising the breathing muscles (inspiratory muscle training) can improve thinking skills when breathing becomes harder. Participants will use special exercises that make their breathing muscles work against resistance.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Active IMTExperimental Treatment1 Intervention
Group II: Sham IMTPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Indiana University

Lead Sponsor

Trials
1,063
Recruited
1,182,000+

United States Air Force Research Laboratory

Collaborator

Trials
3
Recruited
310+

Citations

The Effect of Inspiratory Muscle Training on Cognitive ...

The aim of this clinical study is to examine the effect of an 8-week training program applied to the respiratory muscles that enable breathing in ...

Evaluating the Impact of Inspiratory Muscle Training on ... - PMC

What are the main findings? IMT significantly improves inspiratory and expiratory muscle strength and consistently reduces dyspnea and fatigue, ...

The efficacy of inspiratory muscle training in improving ...

Inspiratory muscle training (IMT) significantly improves respiratory muscle strength, ventilation efficiency, six-minute walk distance, and quality of life (QoL) ...

Investigation of the Effect of Inspiratory Muscle Training ...

The IMT has been shown to improve respiratory and functional outcomes; however, its effects on cognitive function remain unclear.

The effects of inspiratory muscle training on respiratory ...

The results demonstrated that IMT significantly increased vital capacity, maximal inspiratory pressure, and maximal expiratory pressure.

Time-efficient, high-resistance inspiratory muscle strength ...

Time-efficient, high-resistance inspiratory muscle strength training increases cerebrovascular reactivity in midlife and older adults.

The Effect of Inspiratory Muscle Training on Health-Related ...

This study explores the transformative potential of inspiratory muscle training (IMT) to improve the physical functions of college students.

Cognitive and Social Participation Improvements Following ...

(2013) A combined inspiratory and expiratory muscle training program improves respiratory muscle strength and fatigue in multiple sclerosis.