Epic-Based Clinician Notification for Type 2 Diabetes with Albuminuria

Not yet recruiting at 1 trial location
SK
Overseen ByShahzeb Khan, MD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this pragmatic randomized clinical trial is to determine whether an Epic-based clinician notification increases initiation of guideline-directed cardio-kidney-metabolic (CKM) therapies in adults with type 2 diabetes and confirmed albuminuria.

The main question it aims to answer is:

• Does an Epic clinician notification improve initiation of guideline-directed CKM therapies compared with usual care?

Researchers will compare an Epic in-basket clinician notification strategy with usual care.

In the intervention arm, the treating clinician will receive an Epic notification identifying confirmed albuminuria and potential eligibility for guideline-directed CKM therapies using existing electronic health record (EHR) data. Participants in the usual care arm will receive standard clinical care without notification.

Who Is on the Research Team?

SK

Shahzeb Khan, MD

Principal Investigator

Baylor Scott and White Health

Are You a Good Fit for This Trial?

This trial is for adults with type 2 diabetes and confirmed albuminuria (protein in the urine), which means they have signs of kidney problems related to diabetes.

Inclusion Criteria

I am 18 years old or older.
Receiving outpatient care within Baylor Scott & White Health
At least 1 outpatient encounter within the preceding 12 months
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Exclusion Criteria

I am not taking any drugs that interact with this treatment.
My kidney function is too low for SGLT2i or finerenone treatment.
Hyperkalemia or elevated baseline serum potassium precluding safe therapy initiation
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Randomization and Intervention

Participants are randomized to either the Epic clinician notification strategy or usual care. In the intervention arm, clinicians receive notifications about potential eligibility for CKM therapies.

3 months

Follow-up

Participants are monitored for initiation of guideline-directed CKM therapies and clinician responses to notifications.

3 months

What Are the Treatments Tested in This Trial?

Trial Overview

The study compares two approaches: one group has their doctors receive electronic notifications about patients' kidney issues to encourage starting recommended treatments, while the other group receives usual care without these alerts. Participants are randomly assigned to each group.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Epic Clinician NotificationExperimental Treatment1 Intervention
Group II: Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Baylor Research Institute

Lead Sponsor

Trials
210
Recruited
205,000+