N95 Masks and Air Cleaners for COPD

(DS-F Trial)

This trial explores whether N95 masks and air cleaners can help individuals with chronic obstructive pulmonary disease (COPD) breathe easier by reducing exposure to poor air quality. Participants will either receive N95 masks and an air cleaner or receive education about managing COPD. The trial aims to determine if these tools can decrease lung problem flare-ups. It is suitable for non-smoking, oxygen-dependent patients with COPD who have experienced at least two doctor-treated flare-ups in the past year. Participants must be part of the Kaiser Permanente Northern California Care Plus program. As an unphased trial, this study offers a unique opportunity for patients to contribute to innovative research that could enhance COPD management.

The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.

Research has shown that wearing N95 masks for individuals with mild COPD (a lung condition) usually doesn't cause major problems. However, some studies suggest these masks might make breathing harder and increase tiredness during physical activity. They can also affect blood oxygen and carbon dioxide levels.

Researchers are excited about using N95 masks and air cleaners for COPD because these tools offer a non-pharmaceutical approach to managing the condition. Unlike traditional treatments, which often include inhalers, bronchodilators, and steroids to manage symptoms, this method focuses on reducing exposure to harmful airborne particles. By preventing inhalation of pollutants and allergens, this approach could lead to better lung health and improved quality of life for those with COPD without the side effects associated with medications.

This trial will evaluate the use of N95 masks and indoor air cleaners for individuals with COPD. Research has shown that N95 masks can make breathing harder for people with COPD, with some studies finding that wearing these masks can increase breathing difficulty and raise heart rate. However, these masks block harmful particles, potentially reducing exposure to poor air quality. Meanwhile, indoor air cleaners have shown promise in improving lung health in COPD patients. Studies have found that these devices can effectively lower indoor air pollution, which may lead to easier breathing and fewer symptoms. Overall, air cleaners could help create a healthier home for those with COPD. Participants in the intervention arm of this trial will receive both N95 masks and an indoor air cleaner.³⁴⁶⁷⁸