Magnolia Officinalis Supplement for Psoriasis

This trial aims to determine whether Viv, a dietary supplement derived from the Magnolia officinalis plant, can influence immune activity in adults with psoriasis. Participants will take either Viv or a placebo daily for three months. They will complete surveys about their quality of life and symptoms and use at-home blood kits to monitor changes in inflammation. This trial suits adults with stable psoriasis for at least six months who do not need strong immune-suppressing medication and can use a smartphone app. As an unphased trial, it provides an opportunity to contribute to early research on Viv's potential benefits for psoriasis.

The trial does not specify if you need to stop taking your current medications. However, if you have used certain systemic therapies recently, you may not be eligible to participate.

Research has shown that Magnolia officinalis, the plant used to make Viv, is generally safe for most people. Studies have found that extracts from this plant can help reduce inflammation and protect cells, which is important for managing conditions like psoriasis. In past research, supplements made from Magnolia officinalis were linked to improvements in psoriasis symptoms without causing major side effects.

Unlike the standard treatments for psoriasis, which often include topical steroids or systemic medications like methotrexate, the Magnolia officinalis supplement offers a novel approach by using a natural dietary supplement. Researchers are excited about this treatment because Magnolia officinalis is known for its anti-inflammatory properties, which could provide relief with potentially fewer side effects. Additionally, being a dietary supplement, it may offer a more accessible and less invasive option for those seeking alternative therapies. This unique mechanism of action could open up new pathways for managing psoriasis effectively.

Research has shown that Magnolia officinalis might help with psoriasis by reducing inflammation. One study found that people who took supplements from this plant experienced improvements in their psoriasis and changes in blood tests related to inflammation. Another study suggested that Magnolia officinalis might reduce the activity of certain body processes linked to psoriasis. In this trial, participants in the experimental arm will receive the Magnolia officinalis supplement to evaluate its effectiveness in managing psoriasis symptoms by targeting inflammation and related processes. However, more research is needed to confirm these effects in a larger group of people.¹²³⁴⁵