Ultrasound-Guided Access for Peripheral Venous Catheterization
(TVA-2026 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
TruVascular Access - TVA-2026 is a prospective, randomized clinical study evaluating whether ultrasound-guided peripheral vascular access improves first-attempt cannulation success compared with conventional landmark, visualization, and palpation-guided techniques in adults who require clinically indicated peripheral venous access.
Participants will be assigned to either an ultrasound-guided vascular-access workflow or a standard vascular-access workflow. The primary outcome is successful placement of a functional peripheral vascular catheter on the first cannulation attempt. Secondary outcomes include the total number of cannulation attempts, time to successful vascular access, successful access within two attempts, need for rescue or escalation to another vascular-access method, patient-reported procedural pain, access-related complications, catheter function, and operator-reported procedural difficulty.
The study will also collect information about participant characteristics, difficult intravenous access features, vascular anatomy, catheter characteristics, operator experience, and other procedural factors that may influence successful vascular access. These data may be used to identify patient and procedural characteristics associated with first-attempt success and to improve future vascular-access workflows.
Participant safety will take priority over study assignment. If the assigned technique is unsuccessful or clinically inappropriate, the treating clinician may use an alternative or rescue vascular-access method according to applicable clinical practice and study procedures.
Who Is on the Research Team?
Gavin C Solomon, M.D.
Principal Investigator
Truway Health, Inc.
Are You a Good Fit for This Trial?
This trial is for adults who need a peripheral IV line placed as part of their medical care. People with conditions making it unsafe or inappropriate to participate, as judged by the clinical team, will not be included.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Standard Peripheral Vascular Access
- Ultrasound-Guided Peripheral Vascular Access
Trial Overview
The study compares two ways of placing an IV: one uses ultrasound guidance and the other uses standard methods like feeling for veins or looking at them. Participants are randomly assigned to either group to see which method works better on the first try.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants assigned to this arm will undergo clinically indicated peripheral vascular access using real-time ultrasound guidance. The operator will use ultrasound visualization to identify an appropriate peripheral vessel and guide needle and catheter placement according to the standardized TVA-2026 vascular-access workflow. Procedural characteristics, number of cannulation attempts, time to successful access, first-attempt success, complications, rescue procedures, and other protocol-defined outcomes will be recorded.
Participants assigned to this arm will undergo clinically indicated peripheral vascular access using conventional techniques, including visual inspection, palpation, anatomical landmarks, and standard vein-selection methods without initial real-time ultrasound guidance. If vascular access cannot be successfully obtained within protocol-defined limits, clinically appropriate rescue or escalation procedures may be used and documented.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Truway Health, Inc.
Lead Sponsor
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