28 Participants NeededMy employer runs this trial

Pelvic Floor Physical Therapy for Cervical Cancer

UC
SS
Overseen BySarah Sittenfeld
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Cincinnati
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help women with cervical cancer undergoing radiation therapy. The researchers seek to determine if pelvic floor physical therapy, which strengthens the muscles supporting the bladder, intestines, and uterus, can improve recovery after radiation. Participants will begin this therapy four weeks after completing their radiation treatment. It suits women with invasive cervical cancer who plan to undergo radiation and are willing to try pelvic floor physical therapy. As an unphased trial, this study provides a unique opportunity for participants to contribute to groundbreaking research that could enhance recovery options for future patients.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that pelvic floor physical therapy is safe for cervical cancer patients?

Research has shown that pelvic floor physical therapy is generally well-tolerated by patients who have undergone treatments for cervical cancer. Studies indicate that this therapy can enhance pelvic organ function and reduce persistent pelvic pain, common after cancer treatment. For instance, one study found that most patients with pelvic floor issues improved over time with therapy. Another study highlighted its effectiveness in managing pain and discomfort.

Importantly, these findings suggest that pelvic floor physical therapy is safe. The studies reviewed reported no major negative effects linked to this treatment. Overall, the therapy appears to be a safe option for aiding recovery after cervical cancer treatments.12345

Why are researchers excited about this trial?

Researchers are excited about pelvic floor physical therapy for cervical cancer patients because it emphasizes rehabilitation after radiation treatment, which current therapies like chemotherapy and surgery don't address. This therapy specifically targets the pelvic floor muscles, helping to alleviate side effects like pelvic pain and incontinence that often accompany radiation therapy. Unlike standard treatments focused on eradicating cancer, this approach aims to improve quality of life and functional outcomes, offering a holistic benefit that current treatments typically overlook.

What evidence suggests that pelvic floor physical therapy might be an effective treatment for cervical cancer?

Research has shown that pelvic floor physical therapy, which participants in this trial will receive, can greatly aid patients recovering from cervical cancer treatments. Studies have found that these exercises can accelerate the recovery of pelvic organ function. Patients often experience less pain and notice improvements in sexual function and urinary symptoms. This therapy also enhances quality of life by addressing side effects such as ongoing pelvic pain. The evidence consistently highlights the positive effects of this therapy in managing the after-effects of cervical cancer treatment.34678

Are You a Good Fit for This Trial?

This trial is for women aged 18 or older with invasive cervical cancer who are about to receive pelvic radiation therapy (at least 45Gy) and are willing to do pelvic floor physical therapy. Women cannot join if they've had prior pelvic radiation or don't speak English.

Inclusion Criteria

I am scheduled to receive at least 45Gy of radiation to my pelvis.
I am female.
I am willing to do pelvic floor physical therapy.
See 2 more

Exclusion Criteria

I have had radiation treatment to my pelvic area before.
Non-English speaking

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Radiation Therapy

Participants undergo definitive pelvic external beam radiation therapy for cervical cancer

6-8 weeks

Pelvic Floor Physical Therapy

Participants receive pelvic floor physical therapy 4 weeks after completing radiation therapy

4 weeks

Follow-up

Participants are monitored for fecal incontinence, urinary incontinence, sexual symptoms, and quality of life at 3 months after radiation therapy

3 months

What Are the Treatments Tested in This Trial?

Interventions

  • Pelvic Floor Physical Therapy

Trial Overview

The study tests whether starting pelvic floor physical therapy four weeks after finishing pelvic radiation helps reduce problems like pain, weakness, or bladder issues in women treated for cervical cancer. All participants receive the same intervention.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Pelvic floor physical therapyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Cincinnati

Lead Sponsor

Trials
442
Recruited
639,000+

Citations

Analysis of the effectiveness of the application of pelvic floor ...

Implementing pelvic floor rehabilitation exercise for postoperative patients with cervical cancer can speed up the recovery of pelvic organ function.

Effectiveness of Pelvic Floor Physiotherapy Techniques in ...

The findings support the efficacy of pelvic floor physiotherapy in addressing the sequelae of gynecological cancer, contributing to the ...

Improvements following multimodal pelvic floor physical ...

Qualitative data highlighted that reduction in pain, improvement in sexual functioning and reduction in urinary symptoms were the most ...

Effectiveness of Pelvic Floor Muscle and Education-Based ...

Findings suggest that combined (multimodal) therapies, specifically PFM (active > passive) + education therapies, appear more effective for vaginal, overall ...

Multimodal physical therapy proves effective for women ...

A recent study highlights multimodal physical therapy as the only conservative treatment with proven efficacy in managing chronic pelvic pain, ...

Pain and Psychological Outcomes After Rehabilitative ... - PMC

These results suggest that pelvic physical therapy may be useful in treating chronic pelvic pain after cervical cancer treatments.

Correlation of patient reported outcomes and physical ...

Most cervical cancer patients with pelvic floor myofascial disorders improve across time and with treatment. •. Scores on the non-invasive ...

Late Side-effects After Cervical Cancer Treatment

Secondary outcome measures are symptoms and severity of pelvic floor disorders, sexual function, lymphedema, quality of life and level of physical activity.