MRI for Spondylolysis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores the healing of pars stress injuries (tiny fractures in the spine) in young people using MRI scans (Magnetic Resonance Imaging). The aim is to determine if these injuries can heal with proper rest and rehabilitation and to track the healing process over a year. Participants will undergo several MRI scans to help understand natural bone healing, which could guide safe return to activities. The trial seeks individuals aged 12-30 who currently experience back pain and have been diagnosed with a specific type of spinal injury. As an unphased trial, it offers participants the chance to contribute to valuable research that could improve future treatment guidelines for spinal injuries.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that MRI is safe for adolescents and young adults?
Research shows that Magnetic Resonance Imaging (MRI) is a safe and comfortable method for detecting stress injuries in the spine. Studies have found that MRI effectively identifies pars injuries, which are tiny fractures in the spine. This capability helps doctors detect these injuries when other scans might miss them.
Unlike some other imaging methods, MRI does not use radiation, enhancing its safety. Although about 25% of MRI scans might be unnecessary, they cause no harm. Overall, MRI remains a safe choice for patients needing spine imaging.12345Why are researchers excited about this trial?
Researchers are excited about using MRI for spondylolysis because it offers a non-invasive way to potentially improve patient outcomes. Unlike traditional methods, which may rely on static imaging like X-rays or CT scans, MRI provides detailed, dynamic images that can track changes over time. This method could lead to more personalized and timely treatment decisions, especially in the test group where MRI results actively guide clinical care. By offering a clearer picture of how the condition progresses, MRI might help tailor treatments more effectively, addressing the specific needs of each patient.
What evidence suggests that MRI is effective for guiding the healing process of spondylolysis?
Research has shown that MRI, or magnetic resonance imaging, excels at detecting early signs of spondylolysis, a type of stress fracture in the spine. MRI can identify these fractures even when other scans, such as CT scans, might miss them. Early detection is crucial as it allows doctors to treat the injury before it worsens. In this trial, participants in both the test and control groups will receive serial MRIs over 12 months. The test group's images will guide their clinical care outcomes, while the control group's images will not influence clinical care decisions until the 12-month mark. Studies also indicate that MRI effectively assesses both damage and changes in the spine. Overall, MRI is a powerful tool for diagnosing and managing spondylolysis, as it clearly shows the injury and helps track the healing process.16789
Who Is on the Research Team?
Lauren Pringle, MD
Principal Investigator
University of Missouri-Columbia
Are You a Good Fit for This Trial?
This trial is for adolescents and young adults with pars stress injuries, which are fractures in the spine. Participants will need to undergo multiple MRI scans over a year and answer questionnaires during their visits.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo serial MRI scans and complete questionnaires at 2, 4, 6, and 12 months to document healing of pars stress injuries
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MRI
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Missouri-Columbia
Lead Sponsor
GE Healthcare
Industry Sponsor
Fotis Vlachos
GE Healthcare
Chief Marketing Officer since 2024
PhD in Molecular Biology and Biochemistry from the University of Massachusetts, MBA from the Wharton School of the University of Pennsylvania
Peter J. Arduini
GE Healthcare
Chief Executive Officer since 2022
MBA from Northwestern University, BSc in Marketing from Susquehanna University