26 Participants NeededMy employer runs this trial

Exoskeleton for Parkinson's Disease

AP
LM
Overseen ByLucas Michaud, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Centre intégré de santé et de services sociaux de l'Outaouais
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a wearable robotic exoskeleton can improve movement in people with Parkinson's disease and healthy older adults. Participants will use the exoskeleton in various settings to assess its impact on walking, balance, and mobility. The study also seeks to understand users' perceptions of wearing the exoskeleton. Individuals with Parkinson’s who can walk for 30 minutes and healthy older adults meeting similar criteria may qualify for this trial. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance mobility for many.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this exoskeleton is safe for improving mobility in older adults and individuals with Parkinson's disease?

Research has shown that exoskeletons, like the one being tested, are generally safe for people with Parkinson's disease. Studies have found that these devices are well-tolerated, meaning most people can use them without major problems. In one study, researchers tested a portable exoskeleton for walking training and found it safe to use. Participants did not report any significant negative effects, indicating no major side effects. This suggests that the exoskeleton is a safe option for improving mobility and balance.12345

Why are researchers excited about this trial?

Researchers are excited about the exoskeleton for Parkinson's disease because it offers a new way to enhance mobility. Unlike traditional treatments like medications (e.g., Levodopa) or deep brain stimulation that target brain function, the exoskeleton directly supports and augments physical movement. This mechanical assistance can be adjusted to provide varying levels of support, potentially allowing for personalized mobility improvements. By exploring different assistance levels, researchers hope to find the optimal settings that maximize movement benefits and improve the quality of life for people with Parkinson's.

What evidence suggests that this exoskeleton is effective for improving mobility in Parkinson's disease?

Research has shown that using a robotic exoskeleton can help people with Parkinson's disease walk better and improve their memory. One study found that training with these robots significantly improved balance and step length, both crucial for easier movement. Another study demonstrated that exoskeletons can help people walk faster and enhance ankle joint movement. Additionally, exoskeletons have shown promise in helping people regain their ability to stand steadily. In this trial, participants will use the exoskeleton under various conditions to evaluate its effect on mobility. Overall, these findings suggest that exoskeletons could effectively improve movement and balance for individuals with Parkinson's disease.12346

Are You a Good Fit for This Trial?

This trial is for people aged 65 or older, either healthy or with Parkinson's disease (stage 1-4), who can walk at least 30 minutes. People can't join if they have severe blood vessel problems in the legs, high fracture risk, serious memory issues, certain medical devices like pacemakers, are under 152 cm tall, or have other major mobility problems.

Inclusion Criteria

I can walk for at least 30 minutes, with or without minimal help.
I am 65 years old or older and do not have Parkinson's disease.
My Parkinson's disease is at stage 1 to 4.
See 2 more

Exclusion Criteria

I have severe blood vessel problems in my legs that affect my movement or safety.
I have Parkinson's disease and severe osteoporosis or a high risk of fractures.
Participants with Parkinson's disease: Severe cognitive impairment (MoCA < 21)
See 11 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Session 1: Familiarization and Baseline Assessment

Participants undergo clinical assessments, fitting and familiarization with the exoskeleton, and participate in interviews to explore user perceptions.

1 day
1 visit (in-person)

Session 2: Functional Mobility Testing

Participants perform functional mobility tasks with and without the exoskeleton under different assistance levels, while movement is measured using wearable sensors.

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the intervention.

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • Exoskeleton

Trial Overview

The study tests a wearable robotic exoskeleton to see if it helps improve walking and balance in older adults and those with Parkinson's disease. Participants try mobility tasks both with and without the exoskeleton during two lab visits to compare effects and user experiences.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: ConditionsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Centre intégré de santé et de services sociaux de l'Outaouais

Lead Sponsor

Citations

Effect of a soft wearable robot suit with hip extensor assistance ...

Picelli et al. have reported robot-assisted gait training showed significant effects on 10-meter walk test, stride length, cadence, balance, and ...

Effects of a Soft Robotic Exoskeleton for Gait Training on ...

Primary outcomes included gait speed and stride length, while secondary outcomes assessed the percentage of swing phase, ankle joint range of ...

Exercising with a robotic exoskeleton can improve memory ...

Exercising with a robotic exoskeleton can improve memory and gait in people with Parkinson's disease by facilitating progressive exercise ...

Lower-Limb Exoskeletons for Gait Training in Parkinson's ...

Thus, such results, gathered together, suggest that lp-LLEXO has no effectiveness in treating FOG symptoms in PD patients. However, the observed ...

Safety and Efficacy of State-of-the-Art Exoskeleton Technology ...

The purpose of this study is to test the safety and efficacy of using of a portable exoskeleton for walking training in persons with ...

Using gait robotics to improve symptoms of Parkinson's disease

CONCLUSIONS. Functional exercise with a low-profile overground exoskeleton showed promising results for improving memory and gait endurance in people with PD ...