50 Participants Needed

Speech Therapy for Parkinson's Disease

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: State University of New York at Buffalo
Must be taking: Levodopa
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores new methods to help people with Parkinson's disease improve their speech. It aims to connect their speaking ability with their understanding of speech through specific exercises. Participants will engage in activities focusing on learning and distinguishing speech intensity and rate. The trial suits individuals diagnosed with Parkinson's who speak North American English and take medication containing levodopa. Those without other speech or hearing issues may find this trial suitable. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance speech therapy for Parkinson's patients.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it requires participants to use a drug that includes levodopa.

What prior data suggests that this speech therapy is safe for individuals with Parkinson's disease?

Research shows that speech therapy can help people with Parkinson's disease improve their speech and comprehension. This therapy involves learning and practicing control over volume and speed of speech.

Specific safety data from clinical trials for the speech therapy used in this study is not available. However, speech therapy is generally considered safe and non-invasive, as it doesn't involve surgery or medication, so the risk of side effects is low.

Overall, speech therapy for Parkinson's aims to enhance communication and quality of life. Participants in such a trial can expect to focus on exercises that strengthen speaking abilities.1234

Why are researchers excited about this trial?

Researchers are excited about this speech therapy approach for Parkinson's disease because it targets specific aspects of speech production and learning that are often overlooked in traditional therapies. Unlike typical treatments that may focus on general speech exercises, this approach emphasizes speech intensity and rate discrimination and learning. By honing in on these particular speech elements, there’s potential for more tailored and effective improvements in communication for those with Parkinson's.

What evidence suggests that this speech therapy is effective for Parkinson's disease?

This trial will focus on speech therapy interventions for Parkinson's disease. Studies have shown that speech treatments can significantly enhance speaking abilities in individuals with Parkinson's disease. One study found that voice therapy led to greater speech improvements compared to no treatment or just working on pronunciation. Another study demonstrated that intensive speech therapy made speech clearer and easier to understand for those with Parkinson's. Research also suggests that individuals with Parkinson's might better distinguish different sounds when they concentrate on using their voice. These findings support the effectiveness of speech therapy in improving communication for those with Parkinson's disease.25678

Are You a Good Fit for This Trial?

This trial is for native North American English speakers who have been diagnosed with Parkinson's disease and are currently using a medication that includes levodopa. Participants must also be residents of the United States.

Inclusion Criteria

I have been diagnosed with Parkinson's disease.
I am a native North American English speaker.
I am taking medication that contains levodopa.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo behavioral interventions including speech intensity learning, speech intensity discrimination, speech rate learning, and speech rate discrimination

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Speech Learning and Speech Production

Trial Overview

The study aims to understand how people with Parkinson's disease learn and perceive speech. It will explore the relationship between speaking difficulties and understanding speech, potentially leading to new treatments for clearer speech and better comprehension.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Learning and DiscriminationExperimental Treatment4 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

State University of New York at Buffalo

Lead Sponsor

Trials
279
Recruited
52,600+

Citations

Speech Learning and Speech Production in Parkinson's ...

In the context of speech-language therapy, Parkinson's disease (PD) is typically associated with its consequences on speech production. Interventions ...

Speech treatment in Parkinson's disease: Randomized ... - PMC

The current findings, that improvements following voice treatment exceeded those following articulation (ES = 1.53) and no treatment (ES = 2.19), together with ...

Speech and language biomarkers for Parkinson's disease ...

In this narrative review, we synthesised current findings on the potential of speech and language symptoms in PD identification and progression monitoring.

The effects of intensive speech treatment on intelligibility in ...

Our findings demonstrate that intensive speech treatment targeting voice improves speech intelligibility in PD. Taken together with previously reported gains ...

A neurocomputational view of the effects of Parkinson's ...

Meanwhile, PD participants showed better pitch discrimination compared to controls during active voice production. Based on a comprehensive ...

Speech and language biomarkers for Parkinson's disease ...

In this narrative review, we synthesised current findings on the potential of speech and language symptoms in PD identification and progression monitoring.

Speech & Swallowing in Parkinson's

Speech and swallowing challenges are common in Parkinson's disease (PD) and can interfere with important parts of life.

Guidelines for Speech-Language Therapy in Parkinson's ...

Not only does the correlation between the guidelines and the Parkinson's Disease Guideline of the Royal Dutch Society for Physical Therapy (KNGF) from 2004.