Bright Green Light Therapy for Postoperative Pain

(GLOW Trial)

This trial tests whether bright green light therapy can reduce pain after surgery. Researchers aim to determine if this light can also improve other recovery aspects, such as sleep and mood, while potentially reducing the need for pain medication. Participants will receive either bright green light or dim white light for comparison. This trial may suit those planning laparoscopic or robotic surgery at UPMC Shadyside Hospital, with an expected hospital stay of at least two days afterward. As an unphased trial, this study offers a unique opportunity to explore innovative recovery methods that could enhance the post-surgery experience.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that bright green light therapy is generally safe. Studies have found that this light can reduce pain in conditions like migraines and fibromyalgia without major side effects. One study showed that green light boosted the body's natural pain relievers and lowered inflammation in the nervous system.

Bright Green Light Therapy for postoperative pain is unique because it uses light exposure as a non-drug approach to manage pain. Unlike traditional pain relief methods that often rely on medications like opioids or NSAIDs, which can have significant side effects, this therapy employs bright green light to potentially ease pain with minimal risk. Researchers are excited because this method targets the body's response to light, which might provide a safer and more natural alternative to managing pain after surgery. Additionally, the therapy is administered through a convenient, non-invasive light lamp, offering a novel way to potentially reduce pain and improve recovery times in a hospital setting.

Research shows that bright green light therapy, which participants in this trial may receive, might help reduce pain after surgery. Some studies have found that this light can boost the body's natural pain-relieving chemicals, called opioids. Other research suggests that green light might also decrease swelling, aiding in pain relief. Additionally, green light therapy has been linked to better sleep and improved mood, both important for recovery. However, some studies indicate that intense light therapy doesn't always help with pain and might even worsen it. While the results are promising, more research is needed to fully understand its effects. Participants in this trial will be randomized to receive either bright green light therapy or dim white light exposure as a comparator.¹²⁶⁷⁸