Surgical Alignments for Knee Arthritis

This trial tests two methods of knee replacement surgery for individuals with arthritis. Mechanical Alignment (MA) positions the new knee straight, potentially requiring extra cutting. Kinematic Alignment (KA) seeks to match the knee's natural bend with less cutting but demands greater precision. The trial includes participants undergoing knee replacement with specific equipment and who can attend follow-up visits and complete forms. As an unphased trial, it offers patients the chance to contribute to innovative surgical techniques that could enhance future knee replacement outcomes.

The trial protocol does not specify whether you need to stop taking your current medications. However, if you are using chronic opioids, you may not be eligible to participate.

Research shows that both Kinematic Alignment (KA) and Mechanical Alignment (MA) are generally safe methods for knee replacement surgery. Studies have found no major differences in results between these techniques, indicating that patients tolerate both well.

For Kinematic Alignment, one study reported good patient outcomes and stable knee function over five years, suggesting that the procedure remains safe and effective over time. Another review found that KA often results in better knee pain relief and flexibility.

Mechanical Alignment is also considered safe. Research comparing MA and KA found no major differences in patient outcomes or walking ability, demonstrating that MA is also well-tolerated.

Researchers are excited about kinematic and mechanical alignment techniques for knee arthritis because they offer a new approach to knee replacement surgery. Unlike traditional methods, which focus on a one-size-fits-all alignment, kinematic alignment customizes the alignment to mirror the patient's natural knee anatomy. This personalization aims to improve joint function and patient satisfaction. Mechanical alignment, on the other hand, emphasizes a precise, standardized alignment across patients, which could enhance the stability and longevity of the knee implant. These methods may offer better outcomes than current standard practices, potentially leading to faster recovery and improved long-term joint performance.

This trial will compare two surgical alignment methods for knee arthritis: Kinematic Alignment (KA) and Mechanical Alignment (MA). Research has shown that KA in knee replacement surgery often leads to better results than MA. KA typically results in higher patient satisfaction and improved knee function. Studies have found that patients receiving KA experience greater pain relief and more natural movement. For instance, one study found that KA patients scored better on tests measuring knee function, such as the WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) and KSS (Knee Society Score), compared to those with MA. However, some research has found no significant difference in outcomes between the two methods. Overall, while KA may offer some benefits, both approaches can be effective for knee replacement surgery.²⁴⁵⁶⁷