40 Participants NeededMy employer runs this trial

Vira Platform for Opioid Use Disorder

(Project Path Trial)

SR
EA
Overseen ByEvan Ames
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Rhode Island Hospital
Must be taking: Buprenorphine, Methadone
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a digital health platform designed to help individuals with Opioid Use Disorder (OUD) adhere to their treatment. The platform, called Vira, works alongside medications like buprenorphine or methadone to determine if it improves recovery outcomes. Participants will receive support from peer recovery specialists through the app. The trial seeks individuals with OUD who have recently started or restarted treatment with these medications and have access to a smartphone.

As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance recovery support for many.

What prior data suggests that the Vira Platform is safe for individuals with Opioid Use Disorder?

Research has shown that digital tools like the Vira Platform can effectively manage opioid use disorder (OUD). Studies have found that these online tools perform as well as traditional in-person care. They are generally user-friendly, with few reports of negative side effects.

The Vira Platform helps individuals adhere to their treatment plans by offering support through a smartphone app, allowing patients to access help whenever needed. Although specific safety data for the Vira Platform is limited, studies on digital health tools for OUD have not identified major safety concerns, suggesting the platform should be safe for most users.

Overall, digital tools for treating OUD have proven to be safe and effective alternatives to in-person care, making them a promising option for those seeking to enhance their recovery process.12345

Why are researchers excited about this trial?

Most treatments for opioid use disorder, like methadone and buprenorphine, work by activating opioid receptors to help manage withdrawal symptoms and cravings. But the Vira Platform is different because it utilizes an innovative digital approach, potentially offering a personalized and interactive method to support recovery. Researchers are excited about the Vira Platform because it could provide a non-pharmacological tool that complements existing therapies, making it easier for individuals to stay engaged in their treatment and possibly improving overall outcomes.

What evidence suggests that the Vira Platform is effective for Opioid Use Disorder?

Research has shown that digital mental health tools, such as the Vira Platform, can help individuals with opioid use disorder (OUD) remain in treatment longer. In this trial, participants will receive either the Vira Platform or treatment-as-usual. One study found that online solutions for OUD are as effective as traditional care, with patients staying in treatment about 13 days longer over six months. This is significant because remaining in treatment can reduce the risk of overdose and support overall recovery. Additionally, research indicates that long-term treatment for OUD leads to better health, improved job prospects, and fewer legal issues. Digital platforms could offer a promising way to keep individuals engaged and enhance their treatment outcomes.678910

Who Is on the Research Team?

SR

Susan Ramsey, PhD

Principal Investigator

Rhode Island Hospital

Are You a Good Fit for This Trial?

This trial is for people diagnosed with opioid use disorder who are currently taking medication like buprenorphine or methadone. Participants should be willing to use a digital health platform and receive support from peer recovery specialists.

Inclusion Criteria

I have recently started or restarted buprenorphine or methadone treatment.
Current Opioid Use Disorder diagnosis
Access to personal smartphone
See 2 more

Exclusion Criteria

Not fluent in English
I am able to understand and agree to participate in this study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive digital mental health platform interventions delivered by peer recovery support specialists while on buprenorphine or methadone medication

3 months
Regular digital interactions

Follow-up

Participants are monitored for treatment retention, substance use, and other health outcomes

3 months
Assessments at baseline and 3-month follow-up

What Are the Treatments Tested in This Trial?

Interventions

  • Vira Platform

Trial Overview

The study compares standard addiction treatment alone versus standard treatment plus access to the Vira digital mental health platform, which includes support from trained peers. The goal is to see if the app helps patients stay in treatment longer.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Vira PathExperimental Treatment2 Interventions
Group II: Treatment-as-UsualActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Rhode Island Hospital

Lead Sponsor

Trials
275
Recruited
71,400+

Ksana Health

Industry Sponsor

Trials
3
Recruited
290+

Citations

Comparative Effectiveness of Different Treatment Pathways for ...

This comparative effectiveness research study examines associations between opioid use disorder treatment pathways and overdose and opioid-related acute ...

Treatment for Opioid Use Disorder: Population Estimates

In 2022, among the 4% of U.S. adults who needed OUD treatment, only 25% received recommended medications. A larger percentage (30%) received ...

States Should Measure Opioid Use Disorder Treatment to ...

Studies have shown that long-term treatment can lead to better outcomes in employment, health, and criminal justice involvement.28

Digital Mental Health Platform for Enhanced Opioid Use ...

This study focuses on a digital mental health platform called 'Vira' that could potentially help enhance recovery and keep patients engaged in care.

Medications for opioid use disorder: Do they predict ...

Only 1/3 of OUD patient discharges successfully completed treatment. Only 30% of individuals were retained in treatment for at least 180 days. those with ...

Opioid Use Disorder (OUD) Project - ACMT

The ToxIC Opioid Use Disorder (OUD) Subregistry is designed to capture de-identified, detailed information regarding OUD treatment and overdose prevention ...

Personalized Addiction Treatment eHancement

The Vira Platform is a digitally enhanced mental health care platform consisting of a patient smartphone application that utilizes mobile ...

Technologies for Opioid Use Disorder Management - PMC - NIH

The DIRE tool allows clinicians to rate 7 factors (diagnosis, intractability, psychological risk, chemical health risk, reliability risk, social support risk, ...

Development and Evaluation of a Digital App for Patient Self ...

A National Institute on Drug Abuse–funded randomized controlled trial of KIOS to augment in-person treatment of patients with OUD is currently ...

Digital biomarker applications across the spectrum of ...

This review explores the current evidence (and potential) for digital biomarkers monitoring across the spectrum of opioid use.