120 Participants NeededMy employer runs this trial

Family-Based Therapy for Opioid Addiction

SS
Overseen BySandy Solove
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: Ohio State University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new approach to support women with a history of opioid addiction and sex trade involvement who participate in specialty court treatment programs. It aims to determine if an adapted version of Multi-Dimensional Family Therapy (MDFT), a type of family-based therapy, is practical and beneficial for this group. Participants will be randomly assigned to receive either the adapted MDFT alongside their usual treatment or just their usual treatment. Women who have experienced opioid addiction, have been involved in the sex trade, and are currently part of a specialty treatment court program might be suitable candidates, especially if they can identify a family member to join them. As an unphased trial, this study provides a unique opportunity to contribute to innovative treatment approaches that could benefit others in similar situations.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this adapted MDFT intervention is safe?

Previous studies have shown that Multidimensional Family Therapy (MDFT) is well-tolerated. Research indicates that participants generally express high satisfaction with this therapy. For instance, one study found that 95% of participants completed their MDFT treatment, suggesting that most people find it acceptable and manageable.

Additionally, MDFT has effectively reduced substance use and improved behavior in young adults and teenagers without causing significant side effects. These findings suggest that the therapy is generally safe and well-received by participants.12345

Why are researchers excited about this trial?

Researchers are excited about Adapted Multi-Dimensional Family Therapy (MDFT) for opioid addiction because it takes a holistic approach, addressing not just the individual struggling with addiction but involving the entire family in the recovery process. Unlike standard treatments that focus primarily on the individual through methods like individual and group therapy, MDFT aims to improve family dynamics and support systems, which are crucial for long-term recovery. This therapy is unique because it combines therapy sessions with family members, enhancing communication and problem-solving skills, which can lead to more sustainable recovery outcomes.

What evidence suggests that the adapted MDFT intervention could be effective for opioid addiction?

Studies have shown that Multi-Dimensional Family Therapy (MDFT) can be more effective than other treatments for reducing the frequency and severity of substance use in the short term. Research indicates that MDFT lowers the severity of drug abuse problems and improves behavior, particularly in individuals with higher substance use. Participants in past MDFT studies experienced significant reductions in substance use from the start of the study to six months later. MDFT is also considered a promising method for reducing substance use and problem behaviors in young people. In this trial, participants in the "Adapted MDFT + TAU" arm will receive up to 20 sessions of the adapted MDFT intervention alongside their usual treatment services. These findings suggest MDFT might benefit individuals with substance use disorders, including those addicted to opioids.36789

Who Is on the Research Team?

AW

Aaron W Murnan, PhD

Principal Investigator

Ohio State University

Are You a Good Fit for This Trial?

This trial is for women with a history of opioid addiction and involvement in the sex trade who are currently taking part in specialty court treatment programs.

Inclusion Criteria

I identify as a woman.
Meet or have met DSM5 criteria for an Opioid Use Disorder (OUD)
Report current or prior sex trade involvement
See 3 more

Exclusion Criteria

Non-English speaking
I am younger than 18 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive up to 20 sessions of the adapted Multi-Dimensional Family Therapy (MDFT) intervention in addition to treatment as usual (TAU) services

3 months
Up to 20 sessions

Follow-up

Participants are monitored for feasibility and acceptability of the intervention, including assessments of family functioning and mental health

3 months post-intervention

What Are the Treatments Tested in This Trial?

Interventions

  • Adapted Multi-Dimensional Family Therapy

Trial Overview

The study compares an adapted family-based therapy (MDFT) plus usual court program services to just the usual services. Participants are randomly assigned to one group or the other, and their experiences are assessed before and after treatment.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Adapted MDFT + TAUExperimental Treatment2 Interventions
Group II: Treatment As UusualActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ohio State University

Lead Sponsor

Trials
891
Recruited
2,659,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

Effectiveness of Multidimensional Family Therapy With Higher ...

Further, in both studies, MDFT was more effective for the classes with greater overall substance use severity and frequency and more comorbid diagnoses.

Multidimensional Family Therapy for Justice-Involved Young ...

The present study explored the acceptability, feasibility, fidelity, and outcomes of a young adult adaptation of multidimensional family therapy (MDFT).

Effectiveness of Multidimensional Family Therapy for ...

This same trial also showed significantly greater reductions in the severity of substance use problems, as measured using the Personal Involvement with ...

Effects of Multidimensional Family Therapy (MDFT) on ...

MDFT was found to be more effective than other treatments on drug abuse problem severity and drug use frequency in the short run but not in the long run and ...

Implementation Outcome Studies

Feasibility of inpatient and outpatient Multidimensional Family Therapy for improving behavioral outcomes in adolescents referred to residential youth care.

A Unique, Co-Designed Family-Based Therapy

The adapted MDFT seeks to support reductions in opioid use by targeting improvements in family factors (e.g. family conflict/stress, support, ...

Multidimensional Family Therapy: Addressing Co-Occurring ...

This article reviews the clinical interventions and research evidence supporting the use of Multidimensional Family Therapy (MDFT) for adolescents with ...

Multidimensional Family Therapy to reduce alcohol and ...

The YEF outcomes database for substance use contains five outcome measures: Alcohol Use. Disorders Identification Test (AUDIT), Substance and Choices Scale ...

Multidimensional Family Therapy for Justice-Involved ...

Analyses revealed statistically significant decreases in substance use on all indicators from baseline to the 6-month follow-up. Significant ...