Family-Based Therapy for Opioid Addiction
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores a new approach to support women with a history of opioid addiction and sex trade involvement who participate in specialty court treatment programs. It aims to determine if an adapted version of Multi-Dimensional Family Therapy (MDFT), a type of family-based therapy, is practical and beneficial for this group. Participants will be randomly assigned to receive either the adapted MDFT alongside their usual treatment or just their usual treatment. Women who have experienced opioid addiction, have been involved in the sex trade, and are currently part of a specialty treatment court program might be suitable candidates, especially if they can identify a family member to join them. As an unphased trial, this study provides a unique opportunity to contribute to innovative treatment approaches that could benefit others in similar situations.
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this adapted MDFT intervention is safe?
Previous studies have shown that Multidimensional Family Therapy (MDFT) is well-tolerated. Research indicates that participants generally express high satisfaction with this therapy. For instance, one study found that 95% of participants completed their MDFT treatment, suggesting that most people find it acceptable and manageable.
Additionally, MDFT has effectively reduced substance use and improved behavior in young adults and teenagers without causing significant side effects. These findings suggest that the therapy is generally safe and well-received by participants.12345Why are researchers excited about this trial?
Researchers are excited about Adapted Multi-Dimensional Family Therapy (MDFT) for opioid addiction because it takes a holistic approach, addressing not just the individual struggling with addiction but involving the entire family in the recovery process. Unlike standard treatments that focus primarily on the individual through methods like individual and group therapy, MDFT aims to improve family dynamics and support systems, which are crucial for long-term recovery. This therapy is unique because it combines therapy sessions with family members, enhancing communication and problem-solving skills, which can lead to more sustainable recovery outcomes.
What evidence suggests that the adapted MDFT intervention could be effective for opioid addiction?
Studies have shown that Multi-Dimensional Family Therapy (MDFT) can be more effective than other treatments for reducing the frequency and severity of substance use in the short term. Research indicates that MDFT lowers the severity of drug abuse problems and improves behavior, particularly in individuals with higher substance use. Participants in past MDFT studies experienced significant reductions in substance use from the start of the study to six months later. MDFT is also considered a promising method for reducing substance use and problem behaviors in young people. In this trial, participants in the "Adapted MDFT + TAU" arm will receive up to 20 sessions of the adapted MDFT intervention alongside their usual treatment services. These findings suggest MDFT might benefit individuals with substance use disorders, including those addicted to opioids.36789
Who Is on the Research Team?
Aaron W Murnan, PhD
Principal Investigator
Ohio State University
Are You a Good Fit for This Trial?
This trial is for women with a history of opioid addiction and involvement in the sex trade who are currently taking part in specialty court treatment programs.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive up to 20 sessions of the adapted Multi-Dimensional Family Therapy (MDFT) intervention in addition to treatment as usual (TAU) services
Follow-up
Participants are monitored for feasibility and acceptability of the intervention, including assessments of family functioning and mental health
What Are the Treatments Tested in This Trial?
Interventions
- Adapted Multi-Dimensional Family Therapy
Trial Overview
The study compares an adapted family-based therapy (MDFT) plus usual court program services to just the usual services. Participants are randomly assigned to one group or the other, and their experiences are assessed before and after treatment.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participant dyads in this arm will receive up to 20 sessions of the adapted Multi-Dimensional Family Therapy (MDFT) intervention in addition to services received as part of their treatment as usual (TAU) received as part of their specialty treatment court program.
This arm receives the normal services offered through the specialty court treatment program they are currently enrolled in. This typically includes individual and group therapy sessions focused on substance use and mental health, case management, and wrap-around services related to housing and basic needs.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Citations
Effectiveness of Multidimensional Family Therapy With Higher ...
Further, in both studies, MDFT was more effective for the classes with greater overall substance use severity and frequency and more comorbid diagnoses.
Multidimensional Family Therapy for Justice-Involved Young ...
The present study explored the acceptability, feasibility, fidelity, and outcomes of a young adult adaptation of multidimensional family therapy (MDFT).
Effectiveness of Multidimensional Family Therapy for ...
This same trial also showed significantly greater reductions in the severity of substance use problems, as measured using the Personal Involvement with ...
Effects of Multidimensional Family Therapy (MDFT) on ...
MDFT was found to be more effective than other treatments on drug abuse problem severity and drug use frequency in the short run but not in the long run and ...
Implementation Outcome Studies
Feasibility of inpatient and outpatient Multidimensional Family Therapy for improving behavioral outcomes in adolescents referred to residential youth care.
A Unique, Co-Designed Family-Based Therapy
The adapted MDFT seeks to support reductions in opioid use by targeting improvements in family factors (e.g. family conflict/stress, support, ...
Multidimensional Family Therapy: Addressing Co-Occurring ...
This article reviews the clinical interventions and research evidence supporting the use of Multidimensional Family Therapy (MDFT) for adolescents with ...
8.
youthendowmentfund.org.uk
youthendowmentfund.org.uk/wp-content/uploads/2025/08/MDFT_EVAL_PROTOCOL_120825.pdfMultidimensional Family Therapy to reduce alcohol and ...
The YEF outcomes database for substance use contains five outcome measures: Alcohol Use. Disorders Identification Test (AUDIT), Substance and Choices Scale ...
9.
springermedicine.com
springermedicine.com/multidimensional-family-therapy-for-justice-involved-young-adult/25879654Multidimensional Family Therapy for Justice-Involved ...
Analyses revealed statistically significant decreases in substance use on all indicators from baseline to the 6-month follow-up. Significant ...
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