Greek Yogurt for Obesity

JJ
DD
Overseen ByDavid D. Church, PhD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how adding two servings of Greek yogurt daily might affect muscle health, blood sugar control, and brain function in post-menopausal women who are overweight or obese. Researchers compare the effects of skimmed milk Greek yogurt with whole milk Greek yogurt. Women aged 50 to 65 who have not had a menstrual period for at least a year and have a body mass index (BMI) of 25 or higher might be a good fit. As an unphased trial, this study offers participants the opportunity to contribute to valuable research that could improve health outcomes for similar women.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that eating Greek yogurt, whether made from skimmed or whole milk, is generally safe for most people. One study found that yogurt can boost the immune system and improve health markers in people with obesity, suggesting that both types of Greek yogurt are well-tolerated.

For skimmed milk Greek yogurt, results are mixed. Some studies suggest that low-fat dairy, like skimmed milk, might be linked to weight gain. However, these studies do not specifically focus on Greek yogurt and do not directly address safety concerns.

Whole milk Greek yogurt appears safe and may even help reduce obesity and waist size. Studies often find that people who eat full-fat yogurt tend to have lower body weights and a reduced risk of obesity.

Overall, evidence supports the safety of Greek yogurt. Most people can eat it without problems, and it might even offer health benefits, such as better immunity and weight management.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about using Greek yogurt to address obesity because it represents a novel dietary intervention compared to traditional treatments like medication, surgery, or structured diet plans. Unlike most obesity treatments that focus on reducing calorie intake or altering metabolic processes through drugs, Greek yogurt offers a natural, food-based approach. It is rich in protein, which may help increase feelings of fullness and reduce overall calorie consumption. Additionally, the trial compares skimmed and whole milk versions, potentially shedding light on the impact of dairy fat content on weight management. This could pave the way for more personalized dietary recommendations for those struggling with obesity.

What evidence suggests that this trial's treatments could be effective for obesity?

Research has shown that eating yogurt can aid in weight control. In this trial, participants will consume either Skimmed Milk Greek Yogurt or Whole Milk Greek Yogurt. Studies have found that frequent yogurt consumption correlates with lower body weight, less body fat, and smaller waists. Specifically, those who eat whole milk yogurt may experience a reduction in waist size and a lower risk of obesity. Conversely, consuming skim milk yogurt is associated with a reduced likelihood of being overweight or obese. Both types of yogurt are high in protein, which can promote a feeling of fullness and lead to reduced calorie intake.35678

Who Is on the Research Team?

DD

David D Church, PhD

Principal Investigator

University of Arkansas

Are You a Good Fit for This Trial?

This trial is for post-menopausal women who are overweight or have obesity. Participants should generally be in good health aside from their weight status.

Inclusion Criteria

Body mass index ≥25 to <40 kg/m2 or body fat ≥36%
I had a hysterectomy over a year ago and I am at least 55 years old.
Able to provide informed consent
See 3 more

Exclusion Criteria

I have had weight loss surgery in the past 5 years.
Pregnancy or nursing in the prior 12 months
May be excluded at Principal Investigator's discretion if health or body composition is incompatible with study procedures
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume two servings per day of skimmed or whole milk Greek yogurt

1 week

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Skimmed Milk Greek Yogurt
  • Whole Milk Greek Yogurt

Trial Overview

The study compares the effects of eating two servings per day of either skimmed or whole milk Greek yogurt on muscle building, blood sugar control, and thinking skills. Participants are randomly assigned to one of the two yogurt groups.

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: Skimmed Milk Greek YogurtActive Control1 Intervention
Group II: Whole Milk Greek YogurtActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Arkansas

Lead Sponsor

Trials
500
Recruited
153,000+

National Dairy Council

Collaborator

Trials
20
Recruited
1,800+

Citations

Critically Appraised Topic: Low Fat Dairy Intake and BMI

Yogurt consumers (n = 280) had lower prevalence of overweight or obesity, lower BMI-for-age, lower waist circumference, and smaller subscapular skinfold

Why Full-Fat Dairy May Be Healthier Than Low-Fat

Those who frequently ate full-fat butter, milk, and cream had lower obesity rates than those who eschewed dairy fat. “Based on my own research ...

Effect of Yogurt With or Without Probiotic Addition on Body ...

We demonstrated that yogurt administration as a dietary supplement in obesity is able to improve some parameters of the intestinal barrier and from the cells of ...

Review Whole milk dairy foods and cardiometabolic health

Data suggest that greater intakes of full-fat dairy but not low-fat dairy protect against metabolic disorders [56], dyslipidemia [57], and obesity risk [59,60].

Is consuming yoghurt associated with weight management ...

Yoghurt consumption is associated with lower body mass index, lower body weight/weight gain, smaller waist circumference and lower body fat in epidemiological ...

Associations between Yogurt Consumption and Weight Gain ...

Contrary to previous studies, the Women's Health Study found a higher risk of overweight and obesity associated with yogurt consumption. The HR of becoming ...

The Truth About Low-Fat Foods: Are They Good For You?

Skim milk is widely considered healthier than whole milk. However, the truth is not so straightforward. As we saw with yogurt, removing the fat ...

Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated ...

Details and patient eligibility · Aged 50 to 65 years · Body mass index ≥25 to <40 kg/m2 or body fat ≥36% · Able to provide informed consent.