Diet and Exercise for Obesity

NB
ED
Overseen ByEric Doucet, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Ottawa

What You Need to Know Before You Apply

What is the purpose of this trial?

Weight loss is difficult and weight maintenance even worse. The principles of dieting dictate that to maintain weight loss, one has to eat less calories than they did before the diet. However, there is evidence to show that it may be the diet per se and not the weight loss that makes people more hungry and vulnerable to weight regain. This study will explore whether appetite control can be restored to normal levels through an individually tailored increase in calories after weight loss. If supported, the findings from this study could alter the way we view dieting.

Who Is on the Research Team?

ED

Eric Doucet, PhD

Principal Investigator

University of Ottawa

Are You a Good Fit for This Trial?

This trial is for people who are overweight or obese and interested in weight loss. Participants should be generally healthy, as the study focuses on health promotion and obesity prevention.

Inclusion Criteria

Non-smoking
Obese class I-II (30 kg/m2 ≤ BMI < 40 kg/m2)
Weight stable (± 2 kg during the 6 months prior to enrollment)
See 3 more

Exclusion Criteria

I have had heart problems or symptoms of a heart condition.
Current diagnosis of an axis 1 psychiatric disorder (mood, anxiety, and eating disorders)
I am currently pregnant or planning to become pregnant during the study.
See 7 more

What Are the Treatments Tested in This Trial?

Interventions

  • Dietary Intervention
  • Exercise

Trial Overview

The study tests how exercise and personalized diet plans affect hunger and weight maintenance after losing weight. It looks at whether gradually increasing calories can help control appetite better than traditional dieting.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: High Energy FluxExperimental Treatment2 Interventions
Group II: Low Energy FluxPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Ottawa

Lead Sponsor

Trials
231
Recruited
267,000+

Canadian Institutes of Health Research (CIHR)

Collaborator

Trials
1,417
Recruited
26,550,000+