NMT Technology for Neuromuscular Monitoring

MM
MB
Overseen ByMorgan Blazy
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: GE Healthcare
Must be taking: Paralytics
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines a new technology called neuromuscular monitoring technology (NMT), which assists doctors in monitoring muscle response during surgeries involving paralytic drugs. The trial aims to gather feedback from medical professionals on the device's performance and to collect data from it. Suitable candidates for this trial include those undergoing procedures requiring paralytic medication and who can have a sensor placed on their hand or forearm. Individuals with tattoos, scars, or conditions on their arm that might interfere with the sensor may not be suitable for this trial.

As an unphased trial, this study offers participants the chance to contribute to the development of innovative medical technology.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications. However, since it involves procedures requiring paralytic medication, it's best to discuss your current medications with the trial team.

What prior data suggests that this NMT Technology is safe for neuromuscular monitoring?

Research shows that using NMT Technology to check muscle function can make surgeries safer. Studies have found that this technology provides accurate readings of muscle activity during surgery, helping doctors monitor and adjust treatment as needed.

NMT monitoring also enhances anesthesia safety by offering ongoing, clear information that helps predict when a patient will wake from anesthesia. This timely data can smooth recovery and may reduce complications.

Although specific studies do not provide detailed safety data, the use of NMT Technology in hospitals suggests it is generally safe. However, like any treatment, rare side effects or risks may occur, so discussing this with a doctor is advisable.1234

Why are researchers excited about this trial?

Researchers are excited about NMT Technology for neuromuscular monitoring because it offers a new approach to tracking muscle function during surgeries. Unlike traditional methods that often involve more invasive procedures or rely on indirect measurements, NMT Technology uses a sensor directly placed on the patient, providing real-time feedback. This method can potentially enhance surgical precision and patient safety by offering more accurate and immediate monitoring of neuromuscular responses.

What evidence suggests that this NMT Technology is effective for neuromuscular monitoring?

Research has shown that NMT Technology, used to monitor muscles, reduces the need for muscle-relaxing drugs during surgery and lowers the risk of lasting muscle weakness afterward. Studies indicate that this technology offers more stable and accurate readings, preventing errors. Precise monitoring ensures proper muscle recovery after relaxation during surgery, avoiding complications upon waking. These findings suggest that NMT Technology effectively ensures a safe recovery from muscle relaxation during and after medical procedures.3567

Are You a Good Fit for This Trial?

This trial is for adults (18+) who need muscle relaxant drugs during a medical procedure and can give written consent. They'll have their muscle function monitored with an NMT ElectroSensor on the hand/forearm.

Inclusion Criteria

Study subject will have the primary NMT monitoring conducted using an NMT ElectroSensor on the hand/forearm
I am 18 years old or older.
Study subject must have the ability to understand and provide written informed consent
See 1 more

Exclusion Criteria

Direct employees or contractors of GE HealthCare, or any company that makes NMT monitoring devices (sensors, cables, modules)
Breastfeeding
Suffering from an infection(s) that requires isolation
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Placement of NMT Sensor and collection of feedback during standard of care surgical procedure

Up to 24 hours
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 months

What Are the Treatments Tested in This Trial?

Interventions

  • NMT Technology

Trial Overview

The study is testing the NMT EasyFit Sensor and Cable technology, which monitors neuromuscular function in patients receiving paralytic medication during procedures.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: All SubjectsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

GE Healthcare

Lead Sponsor

Trials
307
Recruited
634,000+
Fotis Vlachos profile image

Fotis Vlachos

GE Healthcare

Chief Marketing Officer since 2024

PhD in Molecular Biology and Biochemistry from the University of Massachusetts, MBA from the Wharton School of the University of Pennsylvania

Peter J. Arduini profile image

Peter J. Arduini

GE Healthcare

Chief Executive Officer since 2022

MBA from Northwestern University, BSc in Marketing from Susquehanna University

Loma Linda University

Collaborator

Trials
322
Recruited
267,000+

Citations

Advancements in NMT with train of four monitoring

The study authors concluded that the dose of NMBDs and incidence of residual paralysis decreases with NMT monitoring, and the use of reversal ...

electromyography-based neuromuscular monitoring in ... - PMC

EMG-based monitoring is associated with reduced calibration time, improved stability against signal drift, and superior prevention of residual ...

Advancements in Quantitative Neuromuscular Monitoring

Quantitative neuromuscular monitoring is the only reliable means of confirming adequate recovery from neuromuscular blockade and avoiding postoperative ...

Quantitative Neuromuscular Monitoring in the Operating ...

The Stimpod NMS450X enables you to leverage the power of both AMG and EMG for reliable and accurate quantitative NMT monitoring at your facility.

Patient Safety and Quantitative Neuromuscular ...

The recommendation for NMT monitoring arises from accumulated experiences of residual neuromuscular blockade in postoperative patients, which is not a rare ...

How quantitative neuromuscular monitor is advancing ...

Quantitative NMT monitoring enhances anesthesia safety by providing quantifiable data. These continuous, objective measurements of muscle ...

NMT: Helping to Optimize Recovery from Anesthesia

Monitoring the level of neuromuscular block enables follow-up and prediction of recovery and helps in correct timing of the antagonists, which may decrease the ...