Moisturizers for Skin Dryness in Cancer

CR
Overseen ByClinical Research Coordinator
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Stanford University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether certain moisturizers can reduce skin dryness in cancer patients experiencing skin problems from their treatments. Participants will apply specific La Roche Posay products daily to assess improvements in their skin condition. The trial includes a few clinic visits for skin evaluations and tests before and after product use. Suitable candidates have cancer, are currently receiving treatment, and are experiencing related skin issues.

As an unphased trial, this study provides a unique opportunity to potentially improve skin health while contributing to valuable research.

What prior data suggests that these cosmeceutical topical moisturizers are safe for participants with cancer?

Studies have shown that the La Roche Posay Lipikar AP+ Triple Repair Moisturizing Cream is safe for sensitive skin. Dermatologists have tested it, confirming its safety for the whole family, including those undergoing chemotherapy and radiation. This cream contains no fragrances or parabens and has undergone allergy testing.

The La Roche Posay Cicaplast balm with Panthenol/Vitamin B5 is also part of the study, but specific safety details are unavailable from the sources provided.

The Lipikar Wash Atopy-Prone Plus (AP+) Moisturizing Face and Body Wash is proven safe for sensitive skin, even for babies as young as two weeks. It is fragrance-free and soap-free, tested by dermatologists, and gentle on dry and sensitive skin.

These products are generally well-tolerated and designed for sensitive skin, making them a safe option for those experiencing skin dryness due to cancer treatments.12345

Why are researchers excited about this trial?

Researchers are excited about these moisturizers for skin dryness in cancer patients because they incorporate active ingredients like Panthenol/Vitamin B5, which is known for its soothing properties and skin barrier repair capabilities. Unlike typical moisturizers, these products are specifically designed for atopy-prone skin, offering a targeted approach that addresses the unique needs of skin affected by cancer treatments. Additionally, the combination of a specialized face and body wash and a triple repair cream provides a comprehensive skincare regimen that is gentle yet effective, potentially offering relief and improvement in skin condition faster than standard options.

What evidence suggests that these moisturizers could be effective for skin dryness in cancer patients?

Research has shown that La Roche-Posay Cicaplast Balm B5 effectively aids in skin healing and hydration. Over 96% of users report that it soothes dry and irritated skin, particularly benefiting those undergoing cancer treatments. Participants in this trial will incorporate La Roche-Posay Cicaplast Balm B5 into their regimen.

The La Roche-Posay Lipikar AP+ Triple Repair Moisturizing Cream, also part of the trial regimen, has been proven to help very dry skin stay hydrated for up to 48 hours and is safe for individuals receiving chemotherapy. It is specifically formulated for dry, itchy, and eczema-prone skin.

Additionally, participants will use the La Roche-Posay Lipikar Wash AP+, which dermatologists have tested. It provides gentle cleansing for sensitive skin, including skin affected by cancer treatments. These products aim to relieve skin dryness, a common side effect of cancer treatments.678910

Who Is on the Research Team?

LZ

Lisa Zaba, MD, PhD

Principal Investigator

Stanford University

Are You a Good Fit for This Trial?

This trial is for people with cancer who are experiencing skin problems, such as dryness or irritation, due to their cancer treatments. Participants should be able to visit the clinic for check-ups and follow instructions on using moisturizers.

Inclusion Criteria

I am currently receiving cancer treatment or therapy.
I have been diagnosed with cancer.
I am 18 years old or older.
See 1 more

Exclusion Criteria

Patient is healthy
I am unable to understand what the study involves.
I am not able to give written consent for this study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week
1 visit (in-person)

Treatment

Participants apply cosmeceutical topical moisturizers daily from baseline up until the follow-up visit

2-4 weeks
Daily application at home

Follow-up

Participants visit the clinic for a follow-up visit for a repeat skin evaluation and tests

2-4 weeks
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • La Roche Posay Cicaplast balm Panthenol/Vitamin B5 (B5+)
  • La Roche Posay Lipikar AP+ Triple Repair Moisturizing Cream
  • La Roche Posay Lipikar Wash Atopy-Prone Plus (AP+) Moisturizing Face and Body Wash

Trial Overview

The study tests whether daily use of specific La Roche Posay moisturizers (face/body wash, repair cream, and balm) can improve dry or irritated skin caused by cancer therapies. Skin health will be checked before and after about 2-4 weeks of moisturizer use.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: MoisturizerExperimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Stanford University

Lead Sponsor

Trials
2,527
Recruited
17,430,000+

L'Oreal

Industry Sponsor

Trials
22
Recruited
11,100+

Citations

La Roche-Posay Cicaplast Balm B5: multi-purpose soothing ...

La Roche-Posay Cicaplast Balm B5: multi-purpose soothing cream hydrates cracked, chapped, chafed skin and dry skin irritations.

results of an observational study | Szczech

The results demonstrated significant improvement in skin healing high satisfaction, with over 96% rating the balm's effectiveness as “good” or ...

Cicaplast Balm B5+ | Skin Barrier Cream for Dry, Chapped ...

Cicaplast Balm B5+ is a dermatologist-tested skin barrier cream formulated with Tribioma prebiotic complex, 5% Panthenol, and Madecassoside.

The History of the Hero: La Roche-Posay Cicaplast Baume ...

panthenol – which derives from vitamin B5 – works hard to improve redness and is a humectant that draws in moisture to help keep hydration ...

La Roche-Posay Cicaplast Baume B5 Review

If your skin is dry, sensitive, rough, or easily irritated, a panthenol-and-madecassoside balm can feel like a lifesaver. If you're dealing with ...

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