LASIK Surgery for Near-sightedness
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial compares two types of LASIK eye surgeries to determine which is more effective for treating nearsightedness. Participants will receive wavefront-guided LASIK on one eye and ray tracing-guided LASIK on the other. The trial seeks individuals aged 22 and older with healthy eyes, nearsightedness, similar vision in each eye, and manageable levels of astigmatism (blurred vision due to an irregularly shaped cornea). It is not suitable for those with eye diseases such as glaucoma or cataracts. As an unphased trial, it offers participants the opportunity to contribute to advancements in LASIK technology and improvements in future eye care.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that these LASIK techniques are safe?
Studies have shown that both wavefront-guided and ray tracing-guided LASIK treatments are generally safe for correcting nearsightedness.
For wavefront-guided LASIK, research indicates it is very safe and effective. One study found that almost all patients achieved 20/20 vision or better after one year, and the procedure also improved night vision.
Ray tracing-guided LASIK also demonstrates strong safety results. In one study, it was safe and effective for correcting nearsightedness, with or without astigmatism, and many patients achieved vision better than 20/20.
Both treatments are well-tolerated and have reliably improved vision.12345Why are researchers excited about this trial?
Researchers are excited about these LASIK techniques for near-sightedness because they offer more personalized vision correction. Wavefront-guided LASIK uses detailed measurements of your eye's unique imperfections to tailor the laser treatment, potentially improving visual outcomes beyond standard LASIK. Ray tracing-guided LASIK takes this a step further by using advanced technology to map how light travels through the eye, aiming to enhance precision and accuracy in one eye, compared to wavefront-guided treatment in the other. These cutting-edge methods could lead to sharper, clearer vision and reduce common issues like glare and halos, making them a promising advancement over traditional LASIK options.
What evidence suggests that this trial's LASIK procedures could be effective for near-sightedness?
This trial will compare wavefront-guided LASIK and ray tracing-guided LASIK for treating near-sightedness. Research has shown that wavefront-guided LASIK is highly effective, with 92% of individuals achieving 20/20 vision and 99% achieving 20/40 vision or better. Long-term results indicate that nearly everyone maintained excellent vision for at least four years. Ray tracing-guided LASIK also shows promise. It is considered safe and effective, with half of the treated individuals achieving vision sharper than 20/20. Most participants reported clear distance vision and no issues with near vision. Both methods hold strong potential for improving vision in those with near-sightedness.13456
Who Is on the Research Team?
Edward E Manche, MD
Principal Investigator
Stanford University
Are You a Good Fit for This Trial?
This trial is for individuals aged 22 or older with nearsightedness between -1.00 and -10.00 diopters, and up to 3.00 diopters of astigmatism in each eye, who have similar levels of nearsightedness in both eyes. Participants must not have abnormal corneal shapes, excessively thin corneas, or eye diseases like glaucoma or cataracts.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Examination
Eligible participants are examined preoperatively to establish a baseline for ocular condition
Treatment
Participants undergo wavefront-guided LASIK in one eye and ray tracing-guided LASIK in the fellow eye
Postoperative Evaluation
Participants undergo an ophthalmic evaluation at regular intervals to monitor outcomes
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- LASIK
Trial Overview
The study compares two types of LASIK surgery: wavefront-guided LASIK on one eye and ray tracing-guided LASIK on the other eye for each participant to determine which method is more effective at correcting vision.
How Is the Trial Designed?
2
Treatment groups
Active Control
Wavefront-guided LASIK
Ray-tracing guided LASIK is being performed in one eye and Wavefront-guided LASIK is being performed in the fellow eye
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor
Citations
Ray tracing-guided LASIK for high myopia and astigmatism
Ray tracing-guided LASIK demonstrated favorable safety, efficacy and predictability for high myopia and astigmatism in this study.
Refractive outcome and visual quality of Ray-Tracing Guided ...
This study aimed to evaluate the safety and effectiveness of Ray-Tracing Guided LASIK surgery and to compare the refractive outcomes and visual ...
3.
journals.lww.com
journals.lww.com/jcrs/fulltext/2023/11000/ray_tracing_guided_myopic_lasik__real_world.10.aspxRay-tracing–guided myopic LASIK: real-world clinical...
Ray-trace based LASIK was safe and effective for correction of myopia with and without astigmatism. Approximately, half the eyes achieved ≥20/12.5 UDVA and 8% ...
4.
dovepress.com
dovepress.com/ray-tracing-guided-femtosecond-lasik-refractive-outcomes-visual-qualit-peer-reviewed-fulltext-article-OPTHRay-tracing-guided FS-LASIK: Refractive outcomes, Visual ...
In terms of subjective visual quality, 100% of patients reported clear distance vision, and 96.10% had no near-reading difficulty. Investigation ...
5.
refractivealliance.com
refractivealliance.com/wp-content/uploads/2024/04/Ray-Tracing-Guided-Myopic-LASIK__Real-World-Clinical-Outcomes.pdfRay-tracing–guided myopic LASIK: real-world clinical ...
001). Conclusions: Ray-trace based LASIK was safe and effective for correction of myopia with and without astigmatism. Approximately, half ...
Ray-tracing-guided myopic LASIK: real-world clinical ...
Ray-trace based LASIK was safe and effective for correction of myopia with and without astigmatism. Approximately, half the eyes achieved ≥20/12.5 UDVA and 8% ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.